Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

642 articles for “Clinical”
Set a search alert
Research ArticleOpen accessEvery word in the titleRandomized Clinical Stroke Trials in 2009Meheroz H. RabadiProblem statement: Stroke ranks as the leading cause of serious, long-term disability and death world-wide. It is estimated direct and indirect cost of stroke for 2009 was $68.9 billion. Approach: The objective of this review was to examine the effectiveness of emerging pharmacotherapy’s in patients with acute (≤2 weeks), sub-acute (2-12 weeks) and chronic (≥12 weeks) stroke studied in Randomized … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,250 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRandomized Clinical Stroke Trials In 2008Meheroz H. RabadiProblem statement: Stroke ranks as the third leading cause of death and the leading cause of serious, long-term disability; estimated direct and indirect cost of stroke for 2009 was $68.9 billion. Approach: The objective of this review was to examine the effectiveness of emerging pharmacotherapies in patients with acute (≤2 weeks), sub-acute (2-12 weeks) and chronic (≥12 weeks) stroke studied … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 8,006 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleModeling Heterogeneity in Phase II Clinical TrialsChristopher N. Barnes, Shesh N. RaiProblem statement: The common assumption in non-randomized Phase II clinical trials is a homogeneous population with homogeneous response. This assumption is at odds with many trials today; a heterogeneous response due to the existence of subgroups. Approach: In order to examine the effects of heterogeneity on the trial outcome, a systematic platform is developed to quantify the range and classes … …Current Research in Biostatistics, Vol. 1, Issue 1 · 30 Jun 2010 · 10,131 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,100 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleQuality of Life in Hematologic Cancer Patients: A Randomized Clinical Trial of Low Dose Naltrexone Versus PlaceboMohammad Ali Seifrabiei, Mohammad Abbasi, Ali Montazeri et al.This study aimed to investigate its effect on hematologic cancer patients. This was a randomized controlled trial assessing quality of life in patients with hematologic malignancies from a single institute in Hamedan. Patients were allocated into two study arms and in addition to their routine treatment received either daily naltrexone 3 mg capsules (treatment group) or 3 mg starch (placebo … …American Journal of Applied Sciences, Vol. 5, Issue 7 · 31 Jul 2008 · 7,400 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClinical and Surgical Findings and Outcome Following Rumenotomy in Adult Dairy Cattle Affected with Recurrent Rumen Tympany Associated with Non-Metallic Foreign BodiesZ. Bani Ismail, A. Al-Majali, K. Al-QudahMedical records of 31 adult dairy cows suffering from recurrent rumen tympany for at least 1 month duration that underwent exploratory laparotomy and rumenotomy were reviewed and information was obtained on signalment, history, physical examination findings, laboratory findings and surgical findings. Cases were categorized according to surgical findings into 3 groups. Group 1 (n = 10) included cattle with reticuloruminal, … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 3 · 30 Sep 2007 · 8,931 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleApplications of Real-time Reverse Transcription Polymerase Chain Reaction in Clinical Virology Laboratories for the Diagnosis of Human DiseasesR. Manojkumar, V. MrudulaEarly diagnosis that prevents further expansion of the causative agent and thereby aids control and eradication of infectious agents is critical for countries trying to obtain a particular disease free status. In these diagnostics speed is paramount, including the assay’s applicability, sensitivity, specificity, cost effectiveness and patentability. Real-time Reverse Transcription PCR (rRT-PCR) has revolutionized the field of molecular biology and … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 6,557 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleElectro-diagnostic and Clinical Changes of Peripheral Neuropathies in Bam Earthquake VictimsNaser Zangiabadi, Mohammad Naeem AhrariTo examine and diagnose patients who injured in Bam earthquake at 5:26:52 Am (local time) on Friday, December 26, 2003 with traumatic peripheral neuropathies then treat and follow up. A longitudinal study was deigned. 159 patients with traumatic neuropathies were selected at the first stage of study. After six months follow up only 39 patients satisfied to enter the study. … …American Journal of Environmental Sciences, Vol. 1, Issue 3 · 30 Sep 2005 · 6,719 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIdentification of Venom-Specific Fingerprints of Clinically Relevant Uruguayan Snakes by MALDI-TOFNorma Suarez, Victor MoraisSnakebite envenomation is a particular public health problem in many areas of the world, including extensive areas of Latin America. In particular, in Uruguay, snakebite accidents are caused by two snakes of the genus Bothrops: Bothrops alternatus and Bothrops pubescens. The only effective treatment available is the administration of the specific antivenom. Although there is an ELISA that allows the … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 26 Jul 2019 · 8,212 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMinimum Free Energy Based Evaluation of mRNAs Secondary Structures Constructed by 18 Clinically Significant Exonic Single Nucleotide Polymorphisms (SNPs) and Haplotypes of 5 Missense SNPs of RB1 GeneSarder Nasir Uddin, Apurba Majumder, Khandker Khaldun Islam et al.Clinically significant 18 Single Nucleotide Polymorphisms (SNPs) from exon regions of Retinoblastoma gene (RB1) were analyzed to find out the structural variations in mRNAs. Online bioinformatic tools i.e., Vienna RNA, RNAfold were used for secondary structure analysis of mRNAs. Predicted minimum Free Energy Change (MFE) was calculated for mRNAs structures. It has been observed that the average of predicted MFE … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 21 Oct 2015 · 8,557 accessesView PDFCite