66 results for “Cell Proliferation”

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Research ArticleOpen accessIn the abstractImatinib Mesylate Inhibits Glucose Uptake in Gastrointestinal Stromal Tumor Cells by Downregulation of the Glucose Transporters Recruitment to the Plasma MembraneHans Prenen, Cristiana Stefan, Bart Landuyt et al.Imatinib mesylate, the inhibitor of the KIT protein tyrosine kinase that is constitutively activated in Gastrointestinal Stromal Tumors (GISTs), has been established as the first highly effective drug in the treatment of patients with advanced GISTs. Recent studies suggest that changes in the glucose metabolism could be an additional mechanism of the anti-proliferative action of imatinib. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,245 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDietary supplementation with Cyperus esculentus L (tiger nut) tubers attenuated atherosclerotic lesion in apolipoprotein E knockout mouse associated with inhibition of inflammatory cell responsesMohamed L. Salem, Mohsen Zommara, K. ImaizumiAtherosclerosis is a pathological process, where recruitment of mononuclear cells results in the growth of fibro-fatty plaques. Apolipoprotein E (ApoE) is a legend for the uptake of lipoproteins, and deficiency of ApoE leads to the accumulation of low-density lipoprotein. Utilizing ApoE-/- mouse, which spontaneously develop atherosclerosis on low-fat chow diets, the present study showed that feeding these mice on a … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 10,471 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRooting Responses of Miracle Fruit (Synsepalum dulcificum) Softwood Cuttings as Affected by Indole Butyric AcidXing Wei Chen, Thohirah Lee Abdullah, Nur Ashikin Psyquay Abdullah, Siti Aishah HassanLarge scale productions of miracle fruit (Synsepalum dulcificum) faces some restrictions as the seeds are recalcitrant and propagation by cuttings is difficult to root. When grown from seed, miracle fruit takes 3 to 4 years to begin fruiting. A propagation technique by cuttings needs to be devised to produce early fruiting planting materials. However there has been no report on … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 4 · 4 Dec 2012 · 10,062 accessesView PDF Cite

Review ArticleOpen accessAll words, across the recordMicroRNA-92a: The Administrator of Certain DiseasesZhiyuan Sun, Qing Xu, Xiaoyi Tian et al.MicroRNA-92a (miR-92a) is an evolutionarily conserved noncoding small RNA that can regulate gene expression after transcription. Previous studies have found that miR-92a is overexpressed in many tumors and can regulate numerous tumor suppressor genes negatively, with relevant effects on the development of different tumors, by regulating the DUSP10/c-Jun N-terminal kinase (JNK), phosphatase and tensin homologs (PTEN)/AKT, Wnt and EP4/Notch1 signaling … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 21 May 2020 · 6,494 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordRole of Progranulin Gene Expression as a Molecular Biomarker for Bladder CancerSalwa M. Abo El-khair, Mie A. Mohamed, Tamer E. AlkhiaryBladder cancer is the second most common cancer of the urinary system. Early diagnosis of this tumor and estimation of risk of future progression has a significant impact on prognosis. Although there are several molecular markers for the diagnosis and prognosis for this tumor, their accuracy is not ideal. Progranulin is a growth factor that may play a critical role … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 7,699 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordThe Effect of Salivary Gland Extract of Lucillia Sericata Maggots on the Human Dermal Fibroblasts ProliferationSimona Polakovicova, Stefan Polak, Marcela Kuniakova et al.Problem statement: The aim of study was to investigate the effect of Salivary Gland Extract (SGE) of Lucillia sericata maggots on Human Neonatal Fibroblasts (B-HNF-1) proliferation and migration within collagen/hyaluronan membrane. Chronic, non-healing wounds are major health care problem worldwide. Nowadays, Maggot Debridement Therapy (MDT) has attracted much attention due to its successfull application in a treatment of chronic wounds … …OnLine Journal of Biological Sciences, Vol. 11, Issue 3 · 19 Jan 2012 · 7,641 accessesView PDF Cite