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89 results for “Anti-Inflammatory”
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Research ArticleOpen accessIn the abstractEFFECT OF PIOGLITAZONE ON HEPATIC ULTRA-STRUCTURE AND METABOLIC CHANGES INDUCED BY A HIGH SUCROSE DIET IN RATSMohamed D. Morsy, Ahmed S. Khashaba, Ahmed I. Agamy, Refaat A. EidPioglitazone (Pio) is a PPAR-γ agonist insulin sensitizer has anti-inflammatory activity. Our novel aspect was to investigate its hepatic anti-inflammatory activity at the level of ultra-structure and enzymatic changes in a high sucrose diet animal model. Forty male Sprague Dawley rats were divided into four equal groups: Control; control Pio; high sucrose diet; high sucrose diet Pio treated groups. Fourteen … …American Journal of Applied Sciences, Vol. 11, Issue 7 · 23 Apr 2014 · 6,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractMELATONIN PROTECTS THE INTEGRITY OF GASTRIC STRUCTURE FROM A STERILE TISSUE INJURY AND AUGMENTS BOTH MONONUCLEAR AND POLYMORPHONUCLEAR PERIPHERAL BLOOD CELLS INDUCED BY THE INJURY IN WISTAR ALBINO RATSBahjat Al-AniPeptic ulcer is a common upper gastrointestinal disease that remains a major public health problem. Gastric ulceration caused by Nonsteroidal Anti-Inflammatory Drugs (NSAID), stress and alcohol are the common causes of gastric ulcer formation in humans following helicobacter pylori bacterial infection of the stomach. The neurohormone, melatonin was reported to protect against NSAID- and stress-induced gastric lesions. We sought to … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 17 Mar 2014 · 7,227 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Brief Overview of the Coxib Drugs in the Veterinary FieldTae-Won Kim, Mario GiorgiTraditional Non-steroidal Anti-Inflammatory Drugs (NAIDs) have been widely used to deal with many inflammatory conditions in veterinary medicine. Nowadays however, as the quality of life of animals is improved, new drug options need to be explored. In this review, the authors report on recent trends and the application of the active ingredients labeled for veterinary purposes. …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 2 · 5 Jul 2013 · 13,852 accessesView PDFCite
Research ArticleOpen accessIn the abstractPossible Therapeutic Role of Jasonia Candicans and Jasonia Montana Extracts in the Regression of Alzheimer’s Disease in Experimental ModelHanaa H. Ahmed, Hoda F. Booles, Wagdy K.B. Khalil et al.The present article aimed to investigate the potential role of the ethanolic extracts of the aerial parts of Jasonia candicans and Jasonia montana in management of Alzheimer’s Disease (AD) in experimental model. Supplementation of drinking water AlCl3 (0.3%) for 16 weeks induced AD in male rats with siginifcant increase in brain Acetylcholinesterase (AchE) activity, Tumour Necrosis Factor (TNF-α), Transforming Growth … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 7,830 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Inhibitory Substances on Microbiospora Isolated from Soil under Cultivation of Curcuma Longa L.A. P. Kamble, Prakash Thorat, S. W. KulkarniProblem statement: Soil Pollution is major problem because different types of pesticides are used to control plant pest. The residual component of pesticide diffuses into the soil. It is necessary to check whether actinomycetes degrade these components and control the soil pollution. Approach: In Ayurved system of medicine the rhizome portion of Curcuma longa L. was used as an anti-inflammatory … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 16 Mar 2012 · 7,819 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Microbial, Anti-Oxidant and Anti-Ulcerogenic Effects of Shilajit on Gastric Ulcer in RatsMohamed-I. Kotb El-Sayed, Hatem-K. Amin, Ali-G. Al-KafProblem statement: To evaluate the effects and mechanisms of action involved in anti-ulcer, antioxidant and antimicrobial activities of different native shilajit samples. Approach: Shilajit samples were collected in the mountain region of Yemen (Al-Jouf and Rayma), Russia (Tien-Shan) and India (Kumoan). Stomach ulcers were induced in rats by oro-gastric ingestion of ethanol/HCl. Pre-treatment with ranitidine (100 mg kg-1, p.o.) and … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 1 · 10 Mar 2012 · 8,996 accessesView PDFCite
Research ArticleOpen accessIn the abstractLemon Pepper Fruit Extract (Zanthoxylum acanthopodium DC.) Suppresses the Expression of Inflammatory Mediators in Lipopolysaccharide-Induced Macrophages In VitroYanti, Theodorus Eko Pramudito, Nerissa Nuriasari, Katarina JulianaProblem statement: Lemon pepper fruits (Zanthoxylum acanthopodium DC.; Rutaceae) have been used as a traditional source against stomach ache by Batak people in North Sumatera province, Indonesia. However, its scientific evidence for treatment of inflammatory disorders particularly gastritis has not been reported. Approach: Here, we investigated the inhibitory effects of Lemon Pepper Fruit Extract (LPFE) against inflammatory biomarkers by conducting … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 14 Feb 2012 · 9,581 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Phenylbutazone on Pentylenetetrazole-Induced Seizure in MiceKhayatnouri MirhadiProblem statement: The Cyclooxygenases (COXs), the key enzymes that convert arachidonic acid to Prostaglandins (PGs), had been implicated in physiological and pathophysiological functions in the CNS. Non-Stesoidal Anti-Inflammatory Drugs (NSAIDs), COX inhibitors, were used largely to treat febrile condition, pain state and for prevention of and therapeutics of many diseases. However the role of PGs and NSAIDs in the seizure … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 13 Dec 2011 · 7,675 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Dietary Polydextrose on Clinical Signs of Canine OsteoarthritisA. C. Beynen, D. H.J. Saris, L. De Jong et al.Problem statement: Osteoarthritis is an inflammatory joint disease associated with loss of cartilage matrix. There is suggestive evidence that the intake of polydextrose fiber has anti-inflammatory activity. It was reasoned that polydextrose may have a positive influence on canine osteoarthritis. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of STA-LITE® polydextrose in … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 3 · 5 Oct 2011 · 9,052 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Arthritic Activity of the Methanolic Leaf Extract of Urtica pilulifera L. on Albino RatsSuha Abudoleh, Ahmad Disi, Eyad Qunaibi, Talal AburjaiProblem statement: Urtica pilulifera (Urticeacae) has been used in folk medicine to alleviate inflammation and arthritis. In this study the anti-arthritic effect of methanolic leaf extract of the plant was evaluated and compared to untreated control as well as ibuprofen-treated groups in a rat model of Complete Freund's Adjuvant (CFA)-induced arthritis. Approach: Arthritis was induced by injecting CFA subcutaneously into … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 14 Jun 2011 · 10,431 accessesView PDFCite