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Research ArticleOpen accessIn the abstractUnbalance Quantitative Structure Activity Relationship Problem Reduction in Drug DesignD. Pugazhenthi, S. P. RajagopalanProblem statement: Activities of drug molecules can be predicted by Quantitative Structure Activity Relationship (QSAR) models, which overcome the disadvantage of high cost and long cycle by employing traditional experimental methods. With the fact that number of drug molecules with positive activity is rather fewer than that with negatives, it is important to predict molecular activities considering such an unbalanced … …Journal of Computer Science, Vol. 5, Issue 10 · 31 Oct 2009 · 6,704 accessesView PDFCite
Research ArticleOpen accessIn the abstractBridging Innovation and Access: Randomized, Single-Dose, Open-Label, Parallel-Group Bioequivalence Study of Generic and Innovator Injection Semaglutide in IndiaMayur Madhav Mayabhate, Nitin Kapure, Akhilesh Sharma, Radhakrishna VaddemSemaglutide, a long-acting Glucagon-Like Peptide-1 (GLP-1) receptor agonist, is effective in improving glycemic control, reducing body weight, and lowering cardiovascular risk in Type 2 Diabetes Mellitus (T2DM). Limited accessibility of the innovator formulation underscores the need for bioequivalent generic alternatives. To assess the pharmacokinetic bioequivalence of a synthetic Semaglutide Injection (2 mg/1.5 mL) developed by Alkem Laboratories Ltd., India, compared … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 20 Apr 2026 · 2,626 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Review ArticleOpen accessIn the abstractPrice of Anarchy and Price of Stability Mapping for Analyzing Topology Design of Communication NetworksKanmani S., M. MuraliThe goal of game theory is to model actions among players or users in a common space who deal with various situations and face various outcomes. The study of game theory is widely applied to a wide range of economic fields, including auctions, renewable energy, wireless sensor networks, and software defined networks. Resource allocation and cooperation between networks or terminals … …Journal of Computer Science, Vol. 19, Issue 5 · 15 Apr 2023 · 5,127 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiagnosis of Hepatitis Disease with Logistic Regression and Artificial Neural NetworksAlaa M. Elsayad, Ahmed M. Nassef, Mujahed Al-DhaifallahHepatitis C refers to the inflammatory state of the liver caused by viruses, bacteria, fungi, and exposure to toxins such as alcohol and self-immunity. The diagnosis requires investigating many laboratory tests and comparing the results to those of the former patients with the same conditions. This study presents the results of our experiments to build a hybrid system that combines … …Journal of Computer Science, Vol. 16, Issue 3 · 27 Mar 2020 · 7,466 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Continuous Vaginal Logger-Based Temperature Monitoring in Fever-Induced GiltsMariana Schmidt, Christian Ammon, Peter Schon et al.The aim of this study was to identify a low risk method to induce fever in gilts and to evaluate vaginal sensors for temperature monitoring. Therefore, a rhinitis atrophicans vaccine was used to induce fever to evaluate sensors and behavioral patterns. During 11 trials, two of four animals were injected with 2 mL of the vaccine Porcilis AR-T DF (Intervet) … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 2 · 3 Apr 2013 · 7,666 accessesView PDFCite