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722 articles for “T cells”
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Research ArticleOpen accessIn the abstractElucidating the Mechanism(s) of Hormesis at the Cellular Level: The Universal Cell ResponsePaul S. AgutterMany environmental stressors elicit biphasic effects from single cells. Such cellular hormesis may be interpreted in terms of (a) the superimposition of simple biochemical processes or (b) the non-specific behaviour of the cell. The latter approach is emphasized in this article and identified with the universal cell response (UCR); however, the importance of identifying molecular-level concomitants of the UCR is … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 13,118 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic Interventions in AgingSuresh I.S. RattanSingle or multiple exposure to low doses of potentially harmful agents can have a variety of anti-aging and longevity-extending hormetic effects. These hormetic stressors include irradiation, physical activity, food limitation, heat, hypergravity, dietary components and reactive oxygen species. Molecular mechanisms facilitating the hormetic effects are being elucidated and comprise a cascade of stress response and maintenance and repair pathways. Although … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,833 accessesView PDFCite
Research ArticleOpen accessIn the abstractSignaling Pathways Involved In Dengue-2 Virus Infection Induced RANTES OverexpressionYing-Ray Lee, Huan-Yao Lei, Shun-Hua Chen et al.Dengue viruses participate in liver inflammation by inducting the expression of various chemokines including Regulated on Activation Normal T-cell Expressed and Secreted (RANTES). However, the underlying signaling remains unknown. Here, we reveal that Ras, Raf-1 and three mitogen-activated protein kinases (MAPKs) p38, extracellular signal-regulated kinase (Erk), and c-jun-NH2-terminal kinase (JNK) can be activated or phosphorylated in dengue-2 virus infected hepatocyte … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,176 accessesView PDFCite
Research ArticleOpen accessIn the abstractHeat Balance Analysis During the Production of Jadomycin CT. J. Burdock, A. H. Giffin, M.S. Brooks, A.E. GhalyJadomycins are novel antibiotics that exhibit biological activity against bacteria and yeast and also demonstrate cytotoxicity against cancer cells. Jadomycin C was successfully produced from 10 L of fermentation media in a 19 L bioreactor using Streptomyces venezuelae ISP5230 which was shocked with ethanol. The bioreactor temperature and pH were successfully maintained at 30°C and 7, respectively. The heat of … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 1 · 31 Mar 2008 · 7,715 accessesView PDFCite
Research ArticleOpen accessIn the abstractCellular and Some Biochemical Changes in Blood and Peritoneal Fluid Constituents in Awassi Lambs Following Elective CastrationMohammad B.F. AL-Zghoul, Raida K. AL-Rukibat, Abdelsalam Q. Talafha et al.No reports could be cited in the recent literature concerning the effects of surgical castration on blood and peritoneal fluid constituents in lambs. The purpose of this study was to evaluate the effects of surgical castration on cellular and some biochemical parameters of blood and peritoneal fluid in Awassi lambs. Eight, clinically healthy, 5-month-old, Awassi lambs were surgically castrated. Peritoneal … …American Journal of Animal and Veterinary Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 7,244 accessesView PDFCite
Research ArticleOpen accessIn the abstractRat Cardiomyocytes Express a Classical Epithelial Beta-DefensinAnnika Linde, Gerald H. Lushington, Frank Blecha, Tonatiuh MelgarejoBeta-defensins (BDs) are classical epithelial antimicrobial peptides of immediate importance in innate host defense. Since recent studies have suggested that certain BDs are also expressed in non-traditional tissues, including whole heart homogenate, and because effector molecules of innate immunity and inflammation can influence the development of certain cardiovascular disease processes, we hypothesized that BDs are produced by cardiomyocytes as a … …American Journal of Animal and Veterinary Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 7,000 accessesView PDFCite
Research ArticleOpen accessIn the abstractEstablishment and Evaluation of the Vegetative Community in A Surface Flow Constructed Wetland Treating Industrial Park ContaminantsC.C. Galbrand, A.M. Snow, A.E. Ghaly, R. CôtéA surface flow constructed wetland, designed to curve in a kidney shape in order to increase the length to width ratio to 5:1 was used to treat runoff from an industrial park. A natural wetland system located approximately 200 m downstream of the constructed wetland was selected to act as the vegetative community model for the constructed wetland. The selected … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 7,580 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudies on Metal Microbe Interaction of Three Bacterial Isolates From East Calcutta WetlandV. K. Adarsh, Madhusmita Mishra, Sanhita Chowdhury et al.The present paper put forth the isolation and complete characterization of three bacterial isolates from different sites of East Calcutta Wetland (ECW). These isolates show tolerance to heavy metals like Ag, Al, Cu, Cr, Co, Ni, Pb and were found to be efficient metal accumulators as evident from Energy Dispersive X Ray Fluorescence (EDXRF) analysis and Transmission Electron Microscopy (TEM). … …OnLine Journal of Biological Sciences, Vol. 7, Issue 2 · 31 Dec 2007 · 9,431 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Constructed Wetland Biological Integrity Using Aquatic MacroinvertebratesC. Galbrand, I. G. Lemieux, Abdel E. Ghaly et al.A surface flow constructed wetland consisting of seven cells was used to treat the leachates from a decommissioned landfill. Wetland monitoring was performed by evaluating the treatment efficiency of the landfill leachate and the wetland biological integrity of the wetland. The water quality samples were analyzed for iron, manganese, phosphorus (orthophosphate), pH, dissolved oxygen (DO), nitrogen (ammonia, nitrate, nitrite and … …OnLine Journal of Biological Sciences, Vol. 7, Issue 2 · 31 Dec 2007 · 7,417 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Diabetic Activity of a Fraction from Cissus verticillata and Tyramine, its Main Bioactive Constituent, in Alloxan-Induced Diabetic RatsCleide de Sousa Lino, Thiago de P. Sales, Patrícia B. Gomes et al.Cissus verticillata (syn. C. sycioides, fam. Vitaceae) is a medicinal plant popularly used in Brazil, for the treatment of diabetes mellitus. The anti-diabetic activity of a fraction from leaves of Cissus verticilllata (MSF, methanol soluble fraction), as well as that of tyramine (TYR) were investigated, in the model of alloxan-induced diabetes, in male Wistar rats. The biochemical parameters studied were: … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 8,628 accessesView PDFCite