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Research ArticleOpen accessIn the abstractSpirulina protects against cadmium-induced hepatotoxicity in ratsAmr Amin, Alaaeldin A. Hamza, Sayel Daoud, Waleed HamzaCadmium (Cd) is an environmental and industrial cumulative pollutant that most affects many organs specially the liver. The protective effect of Spirulina, filamentous blue green algae, on Cd – induced oxidative stress and hepatotoxicity was evaluated in male rats. Oral administration of water extract of Spirulina for seven days followed by an acute toxic dose of Cd (3.5 mg kg … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 2 · 30 Jun 2006 · 11,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuropsychological Dysfunction among HIV Infected Drug AbusersRamani S. Durvasula, Charles H. HinkinHuman immunodeficiency virus (HIV) has been documented to cause direct and indirect central nervous system dysfunction that can be observed as a progressive decline in neuropsychological functioning in a large proportion of persons with HIV and AIDS. Neuropsychological decline in individuals with HIV is characterized by cognitive and motor slowing, attentional deficits, executive dysfunction and memory impairment (characterized by intact … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,155 accessesView PDFCite
Research ArticleOpen accessIn the abstractOpiates Upregulate Adhesion Molecule Expression in Brain MicroVascular Endothelial Cells (BMVEC): Implications for Altered Blood Brain Barrier (BBB) PermeabilityMadhavan P.N. Nair, Supriya D. Mahajan, Jessica L. ReynoldsThe blood-brain barrier (BBB) is an intricate cellular system composed of vascular endothelial cells and perivascular astrocytes that restrict the passage of immunocompetent cells into the central nervous system (CNS). Expression of the adhesion molecules, intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on brain microvascular endothelial cells (BMVEC) and their interaction with human immunodeficiency virus (HIV-1) … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,610 accessesView PDFCite
Research ArticleOpen accessIn the abstractLoss of Morphine-induced Suppression of NK Cell activity and T-cell Functions in µ-Opioid Receptor Knockout MiceRichard J. Weber, Ricardo Gomez-Flores, Ichiro Sora, George R. UhlIn vivo administration of µ-opioid receptor selective agonists to various species is known to suppress lymphocyte, NK cell, and macrophage functions, in addition to mediate pain relief and euphoria. Using a mouse model in which the µ-opioid receptor gene was disrupted by targeted homologous recombination, we explored the involvement of this receptor in natural killer (NK) cell activity and T … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 6,937 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Optimization Approach for Selecting Blocks of Embedding Process in Robust Watermarking SystemAbabneh M.F. Mohammad, Naseem M. AsadThis study, discusses several kinds of attacks that may meet the watermarked image such as JPEG compression, Gaussian noise and median filter. The study introduces an approach capable of selecting the optimal blocks in cover image to be used in embedding process. Also, in this study, we propose a technique in robust digital watermarking system looking for finding a relation … …Journal of Computer Science, Vol. 2, Issue 1 · 31 Jan 2006 · 7,171 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Cytokines in the Regulation of Glioma Tumour Growth and AngiogenesisChristina Piperi, Athanasios Zisakis, Robert W. Lea, Anastasios KalofoutisMalignant glioblastomas are the most common type of primary brain tumors accounting for more than 50% of all intracranial gliomas. Due to their aggressive nature, recurrent growth, and their extremely poor prognosis for survival, research approaches have made little progress in advancing treatment of these tumours which have the ability of both modulating host immune function and neutralizing immune-based therapies. … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,868 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparison of Probability Curves Obtained from 2 Quantitative Allergen-specific IgE Assays: FEIA and 3gAllergyTMT. M. Li, T. Chuang, S. M. Li, D. Hovanec-BurnsThe validity and benefit of probability curves in allergen-specific IgE (sIgE) testing and their applicability to more than a few allergens are still pending. One study[1] presented probability curves for 4 food allergens and proposed decision points to rule out the need for food challenges in his clinic. Since then, such cutoffs were reported by Boyano-Martinez[2] to be dependent on … …American Journal of Immunology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,737 accessesView PDFCite
Research ArticleOpen accessIn the abstractGender Differences in Baseline Levels of Vascular Endothelial Growth Factor in the Plasma of Alaskan Sled DogsScott W. Kemp, Arleigh J. Reynolds, Lawrence K. DuffyAngiogenesis and vasculogenesis are two very important processes in the development and maintenance of mammalian health. In sled dogs, the angiogenic role is to supply and support tissue with ample vasculature, thus providing a route of access for the transportation of essential nutrients, including oxygen and the removal of waste in a sustained fashion. VEGF has been shown to be … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,318 accessesView PDFCite