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Research ArticleOpen accessIn the abstractSexual Risk Intervention In Multiethnic Drug And Alcohol UsersDeborah L. Jones, Stephen M. Weiss, Ndashi Chitalu et al.An estimated 38.6 million persons globally are living with HIV, of whom over 1.1 million reside in Zambia. Of the 2 million cases in the US, 64% of new cases among women are among African Americans. Alcohol and drug use represents a significant risk factor for HIV transmission among both Zambians and African Americans. In addition, gender dynamics in both … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,110 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Biopterin Transporter (BT1) Gene on Growth and Infectivity of LeishmaniaManju Jain, Vandana S. Dole, Peter J. Myler et al.Leishmania are known to be auxotrophic for pteridines that are known to play a critical role in the parasites survival. In the present work the role of biopterin transporter in the growth of the parasite and infectivity in to macrophages has been worked out. The role of biopterin transporter in the susceptibility of Leishmania to antimonial compounds has also been … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 7,040 accessesView PDFCite
Research ArticleOpen accessIn the abstractDynamically Reconfigurable Embedded Architecture-An Alternative To Application-Specific Digital Signal Processing ArchitecturesN. Ramadass, S. Natarajan, J. Raja Paul PerinbamEmerging trends in design of real-time digital signal processing systems indicate that in the future, a significant amount of performance improvement can be achieved using dynamically reconfigurable embedded architectures consisting of reconfigurable, general-purpose components. Although embedded real-time systems have long been prevailing in our society, no firm scientific base has been established yet to handle timing requirements in a systematic … …Journal of Computer Science, Vol. 3, Issue 10 · 31 Oct 2007 · 6,735 accessesView PDFCite
Research ArticleOpen accessIn the abstractStandard Versus Specific Therapy for Chronic Osteomyelitis TreatmentAngela Ingianni, Giorgio Lampis, Samuela Laconi et al.58 patients with chronic osteomyelitis were treated either with a standard therapy or with a specific targeted therapy based on the antibiogram assay. Standard therapy was performed by a 15-day course of a parenteral cephalosporin (usually ceftriaxone) in combination with an aminoglycoside (e.g. netilmicin), followed by oral therapy with a fluoroquinolone (generally ciprofloxacin) for 1 to 3 months; specific therapy … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,879 accessesView PDFCite
Research ArticleOpen accessIn the abstractEmetine produce Entamoeba histolytica Death by Inducing a Programmed Cell DeathJ.D. Villalba-Magdaleno, R. Rojas, C. Gómez et al.Amoebiasis is a major public health problem in tropical and subtropical countries. Although a number of antiamoebic agents are used for its treatment and the molecular targets of these drugs have been identified, the biochemical and physiological mechanisms that produce trophozoite death are little known. The present study dates the in vitro induction of programmed cell death (PCD) in E. … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,214 accessesView PDFCite
Research ArticleOpen accessIn the abstractInduced Microcracking Affects Osteoblast Attachment on Hydroxyapatite Scaffolds for Tissue EngineeringIan O. Smith, Melissa J. Baumann, Eldon D. CaseBone microdamage caused by routine activity plays an important role in triggering targeted and nontargeted bone remodeling. Targeted remodeling occurs near localized areas of microdamage[1-4]. We hypothesize that bone remodeling may be directly and positively influenced by inducing microcracks in hydroxyapatite (HA) scaffolds for bone tissue engineering. A study by Case et al. showed microcracking in HA discs having >98% … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,560 accessesView PDFCite
Research ArticleOpen accessIn the abstractHeroin-Induces Differential Protein Expression by Normal Human Astrocytes (NHA)Jessica L. Reynolds, Supriya D. Mahajan, Donald Sykes, Madhavan P.N. NairHeroin use is postulated to act as a cofactor in the neuropathogenesis of human immunodeficiency virus (HIV-1) infection. Astrocytes, integral components of the CNS, are reported to be susceptible to HIV-1 infection. Upon activation, astrocytes release a number of immunoregulatory products or modulate the expression of a number of proteins that foster the immunopathogenesis of HIV-1 infection. However, the role … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,267 accessesView PDFCite
Research ArticleOpen accessIn the abstractLoss of Morphine-induced Suppression of NK Cell activity and T-cell Functions in µ-Opioid Receptor Knockout MiceRichard J. Weber, Ricardo Gomez-Flores, Ichiro Sora, George R. UhlIn vivo administration of µ-opioid receptor selective agonists to various species is known to suppress lymphocyte, NK cell, and macrophage functions, in addition to mediate pain relief and euphoria. Using a mouse model in which the µ-opioid receptor gene was disrupted by targeted homologous recombination, we explored the involvement of this receptor in natural killer (NK) cell activity and T … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 6,941 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Framework for Design of Intelligent Simulation EnvironmentAli Azadeh, Farid GhaderiThis study describes a framework for design and development of intelligent simulation environment. The intelligent simulation environment prescribes an integrated rule-based approach to simulate and optimize a manufacturing system. An intelligent simulation model is a computer program capable of improving its performance by referring to production constraints, system's limitations and desired targets. It is a goal oriented, flexible and integrated … …Journal of Computer Science, Vol. 2, Issue 4 · 30 Apr 2006 · 6,706 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesign of a Neural Networks Classifier for Face DetectionF. Smach, M. Atri, J. Mitéran, M. AbidFace detection and recognition has many applications in a variety of fields such as security system, videoconferencing and identification. Face classification is currently implemented in software. A hardware implementation allows real-time processing, but has higher cost and time to-market. The objective of this work was to implement a classifier based on neural networks MLP (Multi-layer Perception) for face detection. The … …Journal of Computer Science, Vol. 2, Issue 3 · 31 Mar 2006 · 6,887 accessesView PDFCite