76 articles for “toxic effects”

Research ArticleOpen accessIn the abstractUptake of Heavy Metals by Jatropha curcas L. Planted in Soils Containing Sewage SludgeParisa Ahmadpour, Azmi Mat Nawi, Arifin Abdu et al.Problem statement: The chemical pollution of soil has become a major source of concern and has posed serious health problems within the last few years in many developed nations. A variety of organic and inorganic pollutants, including heavy metals, are being mixed in with the cultivated soil and water. Sewage sludge was one of the major sources of enrichment of … …American Journal of Applied Sciences, Vol. 7, Issue 10 · 31 Oct 2010 · 10,271 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAssessment of the Mutagenicity of Some Pharmaceutical EffluentsA. Akintonwa, O. Awodele, A. T. Olofinnade et al.Problem statement: The pharmaceutical industry is a major contributor to industrial wastes globally. Effluents from this industry are usually discharged into the environment and when not properly handled and disposed, they affect both human health and the environment. Approach: This study evaluated the mutagenic potentials of effluents from six pharmaceutical companies in the Lagos province of Nigeria using modified Ames … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,514 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRetinoids Chemosensitize Ovarian Cancer Cell Lines to Cisplatin Independent of Nuclear Receptors and p53Suresh Guruswamy, Doris M. BenbrookTreatment of ovarian cancer with cisplatin-based chemotherapy is highly toxic and is often followed by cancer recurrence. Repeated treatments with cisplatin frequently result in the development of resistance to this drug. Drugs with low toxicity that could enhance the tumor cell killing effects of cisplatin could potentially reduce the toxicity and enhance the efficacy of cisplatin. The mechanism of cell … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,962 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDynamic Kinematics of the Plan Balanced Chain at the Planar Module 3RRelly Victoria Petrescu, Raffaella Aversa, Antonio Apicella, Florian Ion Tiberiu PetrescuAnthropomorphic robots are, as I have already said, in most of the most widespread and widely used works worldwide today, due to their ability to adapt quickly to forced work, working without breaks or breaks 24 h a day, without unpaid leave without asking for food, water, air, or salary. Anthropomorphic robots are supple, elegant, easy to configure and adapted … …Journal of Mechatronics and Robotics, Vol. 2, Issue 1 · 8 Mar 2018 · 6,948 accessesView PDF Cite

Review ArticleOpen accessIn the abstractAbout Homeopathy or ≪Similia Similibus Curentur≫Raffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella, Florian Ion T. PetrescuHomeopathy or homoeopathy (from the Greek όμοιος/homoios, "similar" and πάθος/pathos, "suffering" or "disease") is a science created by Samuel Hahnemann in 1796. The homeopathic practice rests on three principles: The similarity, the individualization of cases and the infinitesimal. The use of the infinitesimal was proposed by Hahnemann in the early nineteenth century with the publication of "Organon der Heilkunst" (Organon … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 16 Dec 2016 · 11,563 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRisk Assessment of Heavy Metals in Fish in Saudi ArabiaOthman M. HakamiHeavy metals such as arsenic, cadmium, mercury and lead constitute a serious threat to human health. Generally, regular consumption of fish is recommended because it is a good source of omega-3 fatty acids, which have been associated with health benefits. However, flesh of some fish species contains heavy metals in high concentration, which may pose health risk for individuals that … …American Journal of Environmental Sciences, Vol. 12, Issue 6 · 3 Dec 2016 · 8,705 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Effect of Bovine Cartilage on the Growth of Mouse B16F10 Melanoma Cells in vitro and in vivoArax Tanelian, Dalal F. Jaber, Nayla S. Al Akl, Alexander M. AbdelnoorEarlier reports indicated that Bovine Cartilage (BC) had anti-tumor effects but only a few in vitro and in vivo investigations were conducted to assess its mechanism of action. The aim of this study was to investigate some of the proposed mechanisms of action of BC on mouse melanoma cells both in vitro and in vivo and to determine if its … …American Journal of Immunology, Vol. 12, Issue 3 · 26 Oct 2016 · 7,491 accessesView PDF Cite

Research ArticleOpen accessIn the abstractApoptosis Inducer Capacity of Cardiotonic Steroids of Urginea maritima Extract on SH-SY5Y Neuroblastoma Cells, with Less Susceptibility among Neuron-Module CellsMaati M. Elghuol, Khalilah Abdul Khalil, Mazatulikhma Mat Zain, Mohamed Saifulaman Mohamed SaidNatural products have played a significant role in conventional treatment and in the development of new drugs for a wide range of illnesses, including malignant disease. Urginea maritima is classified as an herb is endemic to the Mediterranean area. This herb was renowned in traditional ethnopharmacological applications. Notwithstanding, there is a lack of evidence pertaining to the characterization of the … …American Journal of Applied Sciences, Vol. 13, Issue 5 · 28 May 2016 · 7,352 accessesView PDF Cite

EditorialOpen accessIn the abstractThe Food Additives Nitrite and Nitrate and Microbiological Safety of Food ProductsStefanie Müller-Herbst, Anna Mühlig, Jan Kabisch et al.In Germany, raw sausages are typically produced according to a technology referred to as hurdle technology (Leistner, 2000). The combination of several stressful conditions should successfully inhibit growth and survival of pathogenic bacteria, which can be regularly found in raw pork or beef material (Mataragas et al., 2008; Rhoades et al., 2009). Hurdles applied during raw sausage fermentation are the … …Current Research in Microbiology, Vol. 6, Issue 1 · 29 Jun 2015 · 10,382 accessesView PDF Cite

Review ArticleOpen accessIn the abstractSelected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume ParenteralsMohabbat UllahWater For Injections (WFI) which is the main vehicle of Large Volume Parenterals (LVPs) should be free from trace amount of genotoxic impurities. This review gives emphasis on quantification of genotoxic trace metals during qualification of WFI in LVPs manufacturing unit. According to ICH guidelines, impurities related to drug substances are classified into three main categories: Organic impurities, inorganic (elemental) … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 27 May 2015 · 7,710 accessesView PDF Cite