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Research ArticleOpen accessIn the abstractEvaluation of Acute Oral Toxicity Induced by Tablets Based on Ethanolic Extract of Salvia dumetorum Leaves in Experimental RatsYana Levaya, Karakoz Badekova, Mussa Zholdasbayev, Gayane AtazhanovaThe aim of this study was to assess the acute oral toxicity of a solid dosage form based on Salvia dumetorum Andrz. ex Besser leaf extract (SDT5) in experimental rats. Acute toxicity was evaluated over a 14-day observation period following a single oral administration at three dose levels (500 mg/kg, 1000 mg/kg, and 2000 mg/kg), prepared in 0.5 mL of … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 23 Jun 2026 · 1,241 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Multi-Enzyme Machine Cleaning, Multi-Enzyme Soaking, and Traditional Tap Water Cleaning on the Cleanliness of Blood-Contaminated Hemostatic ForcepsLi Kang, Qingmin Gao, Yi FengEffective cleaning of surgical instruments is critical for infection prevention in healthcare settings. This study compared the cleaning efficacy, efficiency, and resource consumption of three methods, multi-enzyme machine cleaning (Group S1), multi-enzyme soaking (Group S2), and traditional tap water cleaning (Group S3), on blood-contaminated hemostatic forceps. A total of 600 blood-contaminated hemostatic forceps collected from the disinfection supply room of … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 24 Apr 2026 · 1,881 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntegrating Higher-Order Thinking Skills, Cognitive Load Theory, and Metacognition in Algebraic Problem-SolvingGurudeo Anand TularamThis study synthesizes 30 years of research (1990–2020) on algebraic problem-solving, integrating Higher-Order Thinking Skills (HOTS), Cognitive Load Theory (CLT), and metacognitive strategies to enhance student outcomes. Utilizing a critical synthesis approach with data from student interviews, problem-solving observations, and longitudinal tracking, the analysis reveals consistent patterns across diverse educational contexts despite limitations and variable factors like teaching styles and … …Journal of Social Sciences, Vol. 22, Issue 1 · 21 Apr 2026 · 2,016 accessesView PDFCite
Research ArticleOpen accessIn the abstractBridging Innovation and Access: Randomized, Single-Dose, Open-Label, Parallel-Group Bioequivalence Study of Generic and Innovator Injection Semaglutide in IndiaMayur Madhav Mayabhate, Nitin Kapure, Akhilesh Sharma, Radhakrishna VaddemSemaglutide, a long-acting Glucagon-Like Peptide-1 (GLP-1) receptor agonist, is effective in improving glycemic control, reducing body weight, and lowering cardiovascular risk in Type 2 Diabetes Mellitus (T2DM). Limited accessibility of the innovator formulation underscores the need for bioequivalent generic alternatives. To assess the pharmacokinetic bioequivalence of a synthetic Semaglutide Injection (2 mg/1.5 mL) developed by Alkem Laboratories Ltd., India, compared … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 20 Apr 2026 · 2,626 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Phytobiotic Carica Papaya Seed Extract on Growth Performance, Physiological Parameters, Gastrointestinal and Immune Organs of BroilersNovi Mayasari, Erna Ainal Mardiah, Selly Masella et al.Papaya (Carica papaya) seeds (PS) are known as a potential phytobiotic alternative to Antibiotic Growth Promotor (AGP) in poultry. Papaya seed extract (PSE) contains bioactive compounds such as carpine, chymopapain, and papain. Two hundred one-day-old Cobb strain broiler chicks were randomly allocated to five dietary treatments with four replicates per treatment, and each replicate consisted of ten birds. During the … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 1 · 13 Apr 2026 · 1,900 accessesView PDFCite
Research ArticleOpen accessIn the abstractSenior Expertise and Peer Consensus: A Comparative Analysis of AI and Clinician Measurements in Multi-Curve Scoliosis AssessmentFrank Ibañez Elijorde, Joselito F. Villaruz, Ma Beth S. Concepcion, Mylo N. SoriasoGiven the scarcity in the literature, this study explored the use of AI for multi-curve scoliosis assessment. Its performance was analyzed through comparison against a group of clinicians composed of one senior and five non-senior orthopedic surgeons. The analysis focused on Cobb angle measurement and identification of vertebral endplates across three curve regions, namely Main Thoracic (MT), Proximal Thoracic (PT), … …Journal of Computer Science, Vol. 22, Issue 3 · 9 Mar 2026 · 1,390 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic and Environmental Interactions in Spring Wheat Resistance to Bipolaris Sorokiniana Root Rot in KazakhstanYerlan Dutbayev, Ardak Bolatbekova, Aidana Kharipzhanova et al.Common root rot caused by Bipolaris sorokiniana represents a major constraint to wheat production in Kazakhstan. This study evaluated the resistance of 30 spring bread and durum wheat genotypes under diverse environmental and treatment conditions in two contrasting regions (Almaty and Aktobe) during 2024. The experimental design included three treatment regimes: fungicide application, artificial inoculation with the pathogen, and natural … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 7 Mar 2026 · 1,517 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficacy of Murraya paniculata Leaf Flour in Reducing Subclinical Mastitis in Dairy Goats Fed Date Pulp-Based DietsDwierra Evvyernie, Endah Yuniarti, Rika Zahera, Anuraga JayanegaraSubclinical mastitis is a major concern in dairy production, leading to economic losses and antibiotic dependence, which poses risks of milk residue contamination. As a natural alternative, orange jasmine (Murraya paniculata) leaves, rich in flavonoids, exhibit antimicrobial and anti-inflammatory properties. This study investigated the effects of incorporating date pulp and orange jasmine leaf flour (OLF) into the diets of lactating … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 21 Feb 2026 · 1,590 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Analysis of Proteins in Two Typical Chinese Thin-Shell WalnutsXu Meng, Tian YilingThis study compared functional properties and molecular characteristics of proteins from two thin-shelled walnut (Juglans regia L.) cultivars predominantly grown in China: Wen 185 and Lvling. Wen 185 walnut protein demonstrated significantly superior performance compared to Lvling across multiple functional parameters, including solubility, emulsifying capacity, foaming capacity, water absorption, and oil absorption. Molecular weight distribution analysis revealed that both proteins … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,481 accessesView PDFCite
Research ArticleOpen accessIn the abstractUnveiling the Potential of Dombeya buettneri K.Schum As a Drug Agent: Molecular Docking of Compounds With Enzymes Linked to Diabetes and Neurodegenerative DiseaseEsther Emem Nwanna, Samuel Chima Ugbaja et al.This study investigated the mechanisms of Dombeya buettneri (snowball leafy) extracts on diabetes, hypertension, and neurodegenerative diseases. It compared extracts obtained using steep water (a by-product of corn wet milling) and aqueous water. The extracts were analyzed for total phenol, total flavonoid content, antioxidant activities such as FRAP, ABTS, NO, DPPH, iron-induced lipid peroxidation assay, degradation of deoxyribose (Fenton’s reaction), … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 1 Feb 2026 · 2,025 accessesView PDFCite