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EditorialOpen accessIn the abstractEditorial Commentary: Challenge of Non–AIDS-Defining Cancers (NADCs), Focusing on Trans Activation Response Element (TAR) RNA Embedding ExosomesLechuang Chen, Ge JinGlobally, 37.9 million people were living with HIV at the end of 2018 (Organization, 2018). Cancer is a major cause of mortality and morbidity in AIDS patients and chronically HIV-infected people. With the aid of combination Antiretroviral Therapy (ART), people living with HIV (PLWH) have a longer life span. However, because the virus is not completely eradicated, PLWH under antiretroviral … …American Journal of Immunology, Vol. 15, Issue 1 · 28 Nov 2019 · 6,657 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplying Neural Network-Based Approach to Sickle Cell Disease-Related Pain ClassificationZacchaeus Omogbadegun, Israel Ogundele, Olufunke OladipupoSickle Cell Disease (SCD), an inherited Red Blood Cell (RBC) disorder, is characterized by anaemia, end-organ damage, unpredictable episodes of pain and early mortality. SCD affects 25% of people living in Central and West Africa causing life threatening “silent” strokes and lifelong damage. Nigeria accounts for 50% of SCD births worldwide (estimated 150,000 of 300,000 babies born with Symptomatic Sickle … …Journal of Computer Science, Vol. 15, Issue 6 · 28 Jun 2019 · 7,678 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhancing Kidney Stone Detection Accuracy Using Image Processing and a Hybrid Convolutional Deep Belief NetworkGeetha M. N, Barkathulla A, S. Nandhini Devi et al.Automated CKD is a rapidly expanding non-communicable ailment that significantly contributes to global mortality and morbidity. CKD impacts more than 10% of the worldwide population, leading to millions of deaths annually. This paper proposes an enhanced deep learning model for renal disease detection that integrates convolutional and involution layers to enhance classification accuracy. CKD is a worldwide health issue characterised … …Journal of Computer Science, Vol. 22, Issue 10 · 9 Oct 2026 · 749 accessesView PDFCite
Review ArticleOpen accessIn the abstractMultidrug Resistant Microorganisms (MDR) and Biofilm Producers: A Challenge for Hospital Infectious ControlDaniel Lucio, Elizabeth Proaño, Alberto Bustillos et al.Antimicrobial Resistance (AMR) now represents a major threat to contemporary health care, especially in hospitals, where repeated antimicrobial exposure selects for and facilitates the dissemination of Multidrug-Resistant (MDR) microorganisms. Biofilm growth adds another layer of persistence by increasing microbial tolerance, supporting long-term colonization of medical devices, and worsening clinical and economic outcomes. This narrative review synthesizes evidence on MDR biofilm-forming … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 12 Sep 2026 · 774 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Vitamin D Deficiency on Cardio Metabolic Ageing in Middle Aged Adults in India: A Comparative AnalysisSumit Kumar, Adithi K, Shailaja S MoodithayaAdvancing age is accompanied by a gradual deterioration in physiological function, resulting in an increased risk of chronic diseases and early mortality. Growing evidence suggests that inadequate vitamin D status may be associated with unfavourable metabolic and cardiovascular alterations. Nevertheless, information regarding the association of vitamin D status with integrated cardio-metabolic biomarkers of ageing in middle-aged adults is currently limited. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 3 Sep 2026 · 732 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Acute Oral Toxicity Induced by Tablets Based on Ethanolic Extract of Salvia dumetorum Leaves in Experimental RatsYana Levaya, Karakoz Badekova, Mussa Zholdasbayev, Gayane AtazhanovaThe aim of this study was to assess the acute oral toxicity of a solid dosage form based on Salvia dumetorum Andrz. ex Besser leaf extract (SDT5) in experimental rats. Acute toxicity was evaluated over a 14-day observation period following a single oral administration at three dose levels (500 mg/kg, 1000 mg/kg, and 2000 mg/kg), prepared in 0.5 mL of … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 23 Jun 2026 · 1,241 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of a Cyclachaena Xanthiifolia Extract on Trematodes Opisthorchis Felineus: An in Vitro StudyDenis Ponomarev, Elena Khramova, Natalia Gubanova et al.Cyclachaena xanthiifolia is a phytochemically rich invasive weed with documented allelopathic properties, making it a candidate source of bioactive compounds with potential medicinal applications. This study investigated the anthelmintic activity of a crude aqueous-ethanolic extract of C. xanthiifolia (CxEt), prepared from equal proportions of leaves and seeds, against the trematode Opisthorchis felineus in vitro. The effects of CxEt on the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 1 Jun 2026 · 1,251 accessesView PDFCite
Literature ReviewOpen accessIn the abstractIntracranial Atherosclerotic Disease: Treatment Potential and Diagnostic OpportunitiesAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Anton Yuvenalievich Postnov et al.Atherosclerosis, characterized by the accumulation of atherosclerotic plaques within large arteries, substantially increases the risk of cardiovascular events, including ischemic stroke. Intracranial atherosclerotic disease (ICAD) represents a particularly significant clinical threat given its strong association with ischemic stroke across multiple intracranial arterial territories. This review provides a comprehensive analysis of the pathogenesis, diagnosis, and management of intracranial atherosclerosis. Special attention … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 5 May 2026 · 1,093 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessing the Comparative Effectiveness of Ensemble CatBoost Versus XGBoost Models in Predicting Heart Disease OutcomesManivannan D., G. Gifta Jerith, G. Chandra Sekhar et al.Cardiovascular Diseases (CVDs) are a common form of heart disease that remains a significant global cause of mortality, responsible for more than 30% of all fatalities. Without intervention, the global fatality count is projected to reach 22 million by 2030. Arterial plaque buildup may impede blood flow, potentially causing heart attacks or strokes. A combination of risk causes, including lack … …Journal of Computer Science, Vol. 22, Issue 4 · 4 May 2026 · 1,544 accessesView PDFCite