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87 articles for “molecular studies”
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Research ArticleOpen accessIn the abstractAqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in VitroAyodeji O. Falade, Goodness I. Omolaiye, Kayode E. Adewole et al.Neurological disorders remain a global health challenge, with Alzheimer’s Disease (AD) as the most famous cause of dementia in old people. Nevertheless, culinary spices and herbs have shown promising potentials in the management of neurological diseases. This study aimed at investigating the neuroprotective property of aqueous extracts of bay leaf (Laurus nobilis) and rosemary (Rosmarinus officinalis) by assessing the antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 25 Jan 2022 · 7,961 accessesView PDFCite
Review ArticleOpen accessIn the abstractApproaches for Conservation of an Ethnomedicinal Plant: Asparagus racemosus Willd.Shubha Thakur, Kishan Lal Tiwari, Shailesh Kumar JadhavIndia is one of the megadiversity regions over the globe, gifted with the immense forest resources having the richness of the medicinal plants. The increasing demand of herbal medicines has led to destructive harvesting practices hampering the existence of natural population. Asparagus racemosus, a female-friendly herb, is one such asset to Indian flora having numerous pharmacological applications. Steroidal saponins are … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 12 Jul 2015 · 7,311 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Cloning and Heterologous Expression of Human Interferon Alpha2b GeneI. Made Artika, Yemima Budirahardja, Anna Lucia EkowatiHuman alpha Interferons (hIFNα) have been shown to have antiviral, antiproliferative and immunomodulatory activities. The human interferon alpha2b (hIFNα2b), is one of the human interferon alpha2 sub variants, naturally synthesized as a polypeptide of 188 amino acid residues, the first 23 residues of which represents a signal peptide. In the present study, the hIFNα2b gene was expressed after being fused … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,840 accessesView PDFCite
Research ArticleOpen accessIn the abstractDose Response and Optical Properties of Dyed Poly Vinyl Alcohol-Trichloroacetic Acid Polymeric Blends Irradiated with Gamma-RaysSusilawati, Aris DoyanProblem statement: The effects of gamma irradiation on optical properties of cresol-red dyed Poly Vinyl Alcohol (PVA) blended with Trichloroacetic Acid (TCA) for possible use in dosimetry and measurement of radiation dose in gamma rays have been studied using both Raman spectroscopy and UV-Visible spectrophotometer method. Approach: The dosimeters are composed of Poly Vinyl Alcohol (PVA), Trichloroacetic Acid (TCA) at … …American Journal of Applied Sciences, Vol. 6, Issue 12 · 31 Dec 2009 · 8,091 accessesView PDFCite
Research ArticleOpen accessIn the abstractPCR Diagnosis for the Identification of the Virulent Gene of Salmonella in Poultry MeatD. K. Zhanabayeva, A. Y. Paritova, G. K. Murzakaeva et al.The purpose of this study was to conduct microbiological studies of poultry meat imported into Mongolia and establish the serotypes and plasmids of Salmonella and determine the virulence of the gene encoding antibiotic resistance and its transmigratory properties. The PCR molecular biological method was used and according to the results, Salmonella enteritidis was identified in chicken carcasses of the American … …OnLine Journal of Biological Sciences, Vol. 21, Issue 3 · 27 Aug 2021 · 6,872 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn silico Assessment of the Arg85Trp Glucokinase Mutation EffectsFaiza Bouldjennet, Souhila Bouaziz-Terrachet, Malha Azzouz, Rachida RaacheMaturity Onset Diabetes of the Young (MODY) is a heterogeneous group of autosomal dominantly inherited, young-onset β-cell disorders that account for approximately 2% of non-insulin-dependent diabetics in Europe. MODY2 or GCK-MODY is caused by inactivating heterozygous mutations in the glucokinase. Linkage of MODY to the Arg85Trp GCK mutation, among Algerian diabetic patients has been established in our previous research. The … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,811 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Effects of Glucocorticoids on Trabecular Meshwork and its Role in GlaucomaAlina GenisPrimary Open-Angle Glaucoma (POAG), an optic neuropathy that is a leading cause of irreversible blindness, has been studied extensively in hopes of better understanding its underlying mechanism. Glucocorticoids (GC) are commonly used to treat inflammatory ocular conditions but are also known to increase the risk of glaucoma by raising Intraocular Pressure (IOP) in susceptible individuals, leading to steroid-induced glaucoma. Based … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 14 Oct 2015 · 8,224 accessesView PDFCite
Review ArticleOpen accessIn the abstractMulti-Timescale Microscopic Theory for Radiation Degradation of Electronic and Optoelectronic DevicesDanhong Huang, Fei Gao, D.A. Cardimona et al.A multi-timescale hybrid model is proposed to study microscopically the degraded performance of electronic devices, covering three individual stages of radiation effects studies, including ultra-fast displacement cascade, intermediate defect stabilization and cluster formation, as well as slow defect reaction and migration. Realistic interatomic potentials are employed in molecular-dynamics calculations for the first two stages up to 100 ns as well … …Space Science International, Vol. 3, Issue 1 · 15 Jun 2015 · 10,238 accessesView PDFCite
Research ArticleOpen accessIn the abstractStem Cells in Traumatic Brain InjurySamuel Dobrowolski, Guilherme LepskiTraumatic Brain Injury (TBI) is a devastating clinical condition that often causes permanent incapacity, especially in the younger population. The clinical relevant of TBI justifies the scientific interest in the pathophysiology of TBI, as well as in protective effects and development of treatment options. Stem cells have the ability to induce neuroprotection and neural repair inflammatory suppression, causing tissue reconstruction … …Neuroscience International, Vol. 4, Issue 1 · 12 Apr 2013 · 7,568 accessesView PDFCite
Research ArticleOpen accessIn the abstractDihydrobiopterin (BH2): Key Determinant in Influencing Arginine Mediated Endothelial Tolerance and DysfunctionSrinidi Mohan, Harsh Patel, Jorge Bolinaga et al.The redox-sensitive tetrahydrobiopterin (BH4) is an essential cofactor that is required by endothelial Nitric Oxide Synthase (eNOS) for L-arginine (ARG) mediated Nitric Oxide (NO) generation. Oxidation of BH4 causes cofactor insufficiency and uncoupling of eNOS, resulting in product switching from NO to O2⋅– production. Here we tested the hypothesis that eNOS uncoupling is not simply a consequence of BH4 insufficiency, … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,354 accessesView PDFCite