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169 articles for “martin”

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Research ArticleOpen accessIn the author namesMortality among HIV-Infected Patients in Resource Limited Settings: A Case Controlled Analysis of Inpatients at a Community Care CenterNirmala Rajagopalan, Joyce B. Suchitra, Anita Shet et al.Problem statement: Despite massive national efforts to scale up Antiretroviral Therapy (ART) access in India since 2004, the AIDS death rate was 17.2 per 100,000 persons during 2003-2005. In the era of HAART in resource poor settings, it is imperative to understand and address the causes of AIDS related mortality. This collaborative study aimed at defining the predictors of mortality … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,664 accessesView PDFCite
Research ArticleOpen accessIn the author namesLife Long Learning: Seniors in Second Life ContinuumC. D. Seals, W. Moses, J. Nyagwencha et al.Senior citizens represented the fastest growing demographic worldwide. As indicated in the Year 2000 US Census, there were 35 million people 65 or older in the US and by 2030, it was estimated that there were about 70 million older adults in the US alone. With the older population growing rapidly and being increasingly exposed to computers and technology, it … …Journal of Computer Science, Vol. 4, Issue 12 · 31 Dec 2008 · 7,116 accessesView PDFCite
Research ArticleOpen accessIn the author namesUsing Thermal Infrared Imagery (TIR) for Illustrating the Submarine Groundwater Discharge into the Eastern Shoreline of the Dead Sea-JordanEmad Akawwi, Abdallah Al-Zouabi, Maher Kakish et al.Many of thermal anomalies that are indicator of discharge zones of warmer water were observed along the Dead Sea shoreline at the areas of Zarka Ma’in, Zara and Al-Mujeb. The groundwater discharge locations were mapped along eastern shores of the Dead Sea by using aerial thermal infrared imagery (λ = 8-13 µm). A digital thermal infrared camera was used for … …American Journal of Environmental Sciences, Vol. 4, Issue 6 · 31 Dec 2008 · 7,421 accessesView PDFCite
Research ArticleOpen accessIn the author namesA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,618 accessesView PDFCite
Research ArticleOpen accessIn the author namesBiochemical and Genetic Responses of Fungi to the Toxic Effect of Synthetic and Natural FungicidesMarÍa-Elena Báez-Flores, Rosalba Troncoso-Rojas, Martin-Ernesto Tiznado-HernándezThe objective of the present review is to analyze the molecular basis of fungicide resistance mechanism to both synthetic fungicides and the natural fungicides isothiocyanates. The review is focused mainly on Alternaria sp., but whenever available, similar studies in other fungi have been included. Fungal resistant strains to dicarboximide and phenylpyrrole fungicides have been found to contain mutations in one … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 8,122 accessesView PDFCite
Research ArticleOpen accessIn the author namesTacrolimus Dosing Challenges in an African American ChildTeresa V. Lewis, Tracy M. Hagemann, Martin A. TurmanIt has been suggested that African Americans have decreased effectiveness with immunosuppressive drugs. Data regarding the pharmacokinetics of tacrolimus in African Americans are limited. We present the case of an African American child in whom management of nephrotic syndrome caused by focal segmental glomerulosclerosis has been challenging due to unpredictable patient specific pharmacokinetic disposition of tacrolimus. Racial differences have been … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2007 · 6,710 accessesView PDFCite
Research ArticleOpen accessIn the author namesRapamycin Inhibits Cystogenesis by Cystic Epithelial Cells Derived from Human Autosomal Dominant Polycystic KidneysGerard Elberg, Teresa V. Lewis, Lijuan Chen, Martin A. TurmanAutosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders and carries a high health burden since it progresses to renal failure in half of the afflicted individuals by the 6th decade of life. Currently, there is no effective treatment to slow the progression of ADPKD. Rapamycin, a drug most commonly used as an immunosuppressive agent … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 7,105 accessesView PDFCite
Research ArticleOpen accessIn the author namesMEDiator: A Tool for Automatic Management of Event DomainsMarkus Aleksy, Lisa Köblitz, Martin SchaderIn this study, we describe our software component MEDiator. Our development is based on OMG’s Management of Event Domains specification. It allows the efficient management and simplified operation of different CORBA Notification Services running concurrently. After a brief introduction into the specifications of the Notification Service and the Management of Event Domains, we describe their architecture and discuss the most … …Journal of Computer Science, Vol. 2, Issue 6 · 30 Jun 2006 · 6,494 accessesView PDFCite
Research ArticleOpen accessIn the author namesEpidemiologic Assessment of the Protective Effects of Smallpox VaccinationHiroshi Nishiura, Isao Arita, Markus Schwehm, Martin EichnerDespite smallpox eradication, the widely discussed possibility of a bioterrorist attack using a variola virus makes it necessary to review the epidemiology of smallpox and the effects of various vaccination schemes. This paper provides a literature review concerning the epidemiologic assessment of the protective effects of smallpox vaccination, with particular emphasis on the statistical and theoretical points of view. Although … …American Journal of Infectious Diseases, Vol. 2, Issue 1 · 31 Mar 2006 · 7,011 accessesView PDFCite
Research ArticleOpen accessIn the author namesSome Fast Methods for Fitting Some One-parameter Spatial ModelsR. J. MartinIt is common in geographic modelling to use a one-parameter spatial model to specify the inverse covariance matrix in terms of I-βW, for some known matrix W. Exact Gaussian maximum likelihood estimation of β requires evaluation of the determinant of the covariance matrix. For large data sets, this evaluation of the determinant can be slow and good approximations can be … …Journal of Mathematics and Statistics, Vol. 1, Issue 4 · 31 Dec 2005 · 6,071 accessesView PDFCite