Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

66 results for “immunodeficiency”
Set a search alert
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite
Research ArticleOpen accessIn the abstractPREVALENCE OF AUTOANTIBODIES REVEALS A PREDOMINANT SMA AND ANCA-PR3/MPO PATTERN IN HIV INFECTION AND SMA IN HAV-INFECTED CHILDRENLuz M. Navarta, Carlos A. Espul, Nelson Acosta-RiveroHepatitis A Virus (HAV) and Human Immunodeficiency Virus (HIV) have been associated with development of autoantibodies and autoimmune manifestations in children. Autoimmune Hepatitis (AIH) is particularly aggressive in children/adolescents with a more severe outcome. Thus, studying the mechanisms of virus-related autoimmune disorders in children is a relevant topic of research. We aimed to study the prevalence of autoantibodies in plasma … …American Journal of Immunology, Vol. 10, Issue 3 · 18 Sep 2014 · 7,038 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntiretroviral Toxicity and Oxidative StressAdikwu Elias, Brambaifa Nelson, Deo Oputiri, Oru-Bo Precious GeoffreyAntiretroviral drugs are used for the treatment of human immunodeficiency virus, they are used as combination regimens to achieve the highest possible benefit, tolerability, compliance and to diminish the risk of resistance development. Reports from preclinical and clinical studies have linked antiretrovirals with some toxicological effects which could be associated with redox imbalance (oxidative stress). This stimulated us to review … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 20 Nov 2013 · 8,255 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiagnosis Value of Bone Marrow Study in the Disseminated Infection by Mycobacteria: Case ReportAna Guadalupe Mauricio Campos, Francisco De Paz Andres, Paola Beneit et al.The bone marrow examination is useful in order to get an etiologic diagnosis of cytopenias and for the detection of opportunistic diseases in immunocompromised patients. Nevertheless, its role in the diagnosis of invasive infections caused by mycobacterium has not been clearly defined. We describe the case of a 42-year-old woman who was admitted to study anemia, diarrhea and constitutional syndrome … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 9 Oct 2012 · 7,829 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficient Anaerobic Fermentation of Simple Sugars by Yeast Fuels Resistance Candida spp. Infections to Eradication by DrugsNedosa Ikenna Valentine, Utoh-Nedosa Uchechukwu Anastasia, Dan Danjuma et al.Problem statement: Human systemic Candida infections had proved difficult to eradicate by the medical health care system. Some practitioners and scholars see the problem as being due to drug resistance. For example an author wrote that ‘secondary drug resistance is clearly being encountered in one setting, oropharyngeal candidiasis in patients with advanced Human Immunodeficiency Virus type 1 (HIV-1) infection usually … …American Journal of Infectious Diseases, Vol. 7, Issue 4 · 10 Dec 2011 · 7,836 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Docking Analysis on Natural Compounds Versus a Synthetic Drug as a Therapeutic for Acquired Immuno Deficiency SyndromeSandhya R. Nair, R. Subhashini, B. ThiagarajanProblem statement: Acquired Immune Deficiency Syndrome (AIDS) is one of the worst pandemics affecting and spreading quickly all over the world with a high mortality rate. AIDS has been able to kill so many people due to the unique property of Human Immunodeficiency Virus (HIV) virus. It attacks the immune system of the victim there by not allowing the immune … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,323 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A ReviewBryan P. Irish, Zafar K. Khan, Pooja Jain et al.Problem statement: Infection with retroviruses such as human immunodeficiency virus type 1 (HIV-1) and human T cell leukemia virus type 1 (HTLV-1) have been shown to lead to neurodegenerative diseases such as HIV-associated dementia (HAD) or neuroAIDS and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP), respectively. Approach: HIV-1-induced neurologic disease is associated with an influx of HIV-infected monocytic cells across the blood-brain … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 14,888 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunodeficient Parameters in the HIV-1 Transgenic Rat ModelSulie L. Chang, Frank Ocasio, Jose A. BeltranRecently an HIV-1 transgenic (HIV-1Tg) rat model was created that carries a gag-pol-deleted HIV-1 genome under the control of the HIV-1 viral promoter. However, other viral proteins are expressed in most organs and tissues, and are found in the circulating blood. Since HIV-1 targets the immune system in humans, we examined two immunological parameters, leukocyte-endothelial adhesion (LEA) and inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,834 accessesView PDFCite
Research ArticleOpen accessIn the abstractMedical Consequences of Drug Abuse and Co-occurring Infections: A Brief ReviewJag H. KhalsaToday substance abuse remains one of the major problems in the world with millions of people abusing legal and illegal drugs. In addition, almost one-third of the world population of 6.7 billion people may also be infected with one or more infections. Both drugs of abuse and infections are associated with enormous burden of social, economic and health consequences. This … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractHIV-1 Infection and Central Monoamine NeurotransmittersAdarsh M. Kumar, J. B. Fernandez, Irina Borodowsky et al.Human immunodeficiency virus type 1 (HIV-1) enters the central nervous system (CNS) shortly after infection and gets localized in different brain regions, leading to various types of neuropathological problems. It has been hypothesized that HIV-1 infection mediated neuropathogenesis may also adversely affect the activity of the central monoamine neurotransmitters systems, such as dopamine (DA), and 5-hydroxytryptamine (5-HT, serotonin), resulting in … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,491 accessesView PDFCite