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Research ArticleOpen accessIn the abstractAnti-Metalloproteinase-9 Activities of Selected Indonesian Zingiberaceae Rhizome Extracts in Lipopolysaccharide-Induced Human Vascular Endothelial Cells In VitroYantiProblem statement: Atherosclerosis is associated with chronic inflammation triggered by bacterial infection that activates the breakdown of extracellular matrix protein by matrix Metalloproteinases (MMPs). Zingiberaceae, a group of tropical food crops grown in Indonesia and other Southeast Asia regions, has been traditionally used for food coloring, seasoning, culinary and medicinal purposes. However, its efficacy as natural vascular protection has not … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 7,874 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Vitamin A on Growth Performance, Antioxidant Status and Blood Constituents in Lactating Grey GoatWeiren Yang, Ping Wang, Yuanqiang Jing et al.Problem statement: It is regarded that vitamin A protects cells from damage by radicals which are believed to contribute to certain chronic diseases and regulates immune function of animals by protection of mucosal epithelium acting as the first defense barrier. All these properties of vitamin A may be attributable to its antioxidant activity. This study was to evaluate the effects … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 4 · 27 Dec 2010 · 7,678 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhysiological Study on the Effect of Acalypha wilkesiana Leaves Extract on Streptozotocin-Induced Experimental Diabetes in Male MiceAtef M. Al-AttarProblem statement: Diabetes mellitus is a chronic disease that causes serious health complications and it is now one of the most common non-communicable diseases globally. It is the fourth or fifth leading cause of death in most high-income countries and there is substantial evidence that it is epidemic in many economically developing and newly industrialized nations. Recently, there has been … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 74,650 accessesView PDFCite
Research ArticleOpen accessIn the abstractExtraction of Protein from Common Plant Leaves for Use as Human FoodA.E. Ghaly, F. N. AlkoaikProblem statement: Protein deficiency is one of the major nutritional problems in the developing world. The most disastrous consequences occur in children where protein malnutrition manifests itself in forms of two notorious diseases: Marasmus and kwashiorkor. Expansion of present agricultural practices into marginal lands is expected to solve this chronic protein shortage. The process of photosynthesis is the only non … …American Journal of Applied Sciences, Vol. 7, Issue 3 · 31 Mar 2010 · 12,021 accessesView PDFCite
Research ArticleOpen accessIn the abstractAtopic Dermatitis and Type 1 Diabetes Mellitus in Iranian ChildrenElham Ahmadi, Zahra Rahnama, Ali Rikhtegaran TehraniProblem statement: Atopic diseases, including asthma, eczema and allergic rhinitis, are characterized by a chronic inflammatory reaction mediated by T helper 2 cells, while type 1 diabetes mellitus is mediated by T helper 1 cells. Approach: The aim of this study was to compare the prevalence of atopic dermatitis between children with type 1 diabetes mellitus and age-matched controls. We … …American Journal of Immunology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,011 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpidemiology of Human Herpesvirus Type 8 Infection in Cardiopathic PatientsAngela Ingianni, Maria A. Madeddu, Francesca Carta et al.Problem statement: The possible contribution of viruses to vascular pathology is still a controversial issue. Human herpesvirus type 8 (HHV-8) has been suggested to participate to the pathogenetic events associated with atherosclerotic lesion establishment and progression. Recently, a high incidence of infection of HHV-8 (11%) has been verified in the island of Sardinia. The aim of this study was to … …OnLine Journal of Biological Sciences, Vol. 9, Issue 2 · 30 Jun 2009 · 7,337 accessesView PDFCite
Research ArticleOpen accessIn the abstractProgressive Resistance Training on Elderly HIV+ Patients: Does it Work?Paula Maria Loiola De Souza, Wilson Jacob Filho, José Maria Santarém et al.Elderly people present significant alterations on body composition and physical fitness, compromising their quality of life. Chronic diseases, including HIV/AIDS, worsen this situation by increasing aging effects on body composition and muscle strength. Resistance exercises are prescribed by major health organizations for improving fitness and promoting a shift towards a healthier and more independent aging. In addition, recovering strength and … …American Journal of Infectious Diseases, Vol. 4, Issue 4 · 31 Dec 2008 · 6,746 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidence of Mitochondrial Dysfunction in Autism and Implications for TreatmentDaniel A. Rossignol, J. Jeffrey BradstreetClassical mitochondrial diseases occur in a subset of individuals with autism and are usually caused by genetic anomalies or mitochondrial respiratory pathway deficits. However, in many cases of autism, there is evidence of mitochondrial dysfunction (MtD) without the classic features associated with mitochondrial disease. MtD appears to be more common in autism and presents with less severe signs and symptoms. … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 16,389 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetection of IL-17 and IL-23 in Plasma Samples of Children with AutismAmanda Enstrom, Charity Onore, Irva Hertz-Picciotto et al.Interleukin-23 (IL-23) is a survival factor for a newly described population of T lymphocytes, namely Th-17 cells, that secrete IL-17, tumor necrosis factor- alpha (TNFα) and IL-6. It has been shown that Th-17 cells are a pathogenic T cell subset involved in autoimmune and chronic inflammatory diseases. Based on the increasing evidence of immune dysfunction in autism, including possible autoimmune … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 8,228 accessesView PDFCite
Research ArticleOpen accessIn the abstractHigh Case-Fatality Rate of Adults With Dengue Hemorrhagic Fever During An Outbreak In Non-Endemic Taiwan: Risk Factors For Dengue-Infected EldersChing-Chuan Liu, Kao-Jean Huang, Mei-Chih Huang et al.In 2002, a dengue outbreak occurred in Taiwan with 5336 confirmed cases, 242 DHF and 21 death, the case fatality rate reached 8.7% (21/242). The demographic data of these age-specific dengue patients showed that dengue virus infection caused symptom primarily occurred in adults. A comparative analysis of clinical and laboratory data for DF, DHF/DSS and fatal DSS found that high … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 8,003 accessesView PDFCite