54 results for “adaptive response”

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Research ArticleOpen accessIn the abstractRal-Binding Protein is Required for the Maturation and Function of Dendritic CellsJozef Borvak, Mukesh Sahu, Varun Joy et al.Problem statement: Dendritic Cells (DCs) integrate responses of innate and adaptive immune system via transmitting pro-inflammatory and regulatory signals to naïve cells within draining lymph nodes. DCs have high capacity for endocytosis, both Clathrin-Dependent (CDE) and Caveolin-Dependent (CvDE). Approach: We have recently shown that ATP-hydrolysis by the multifunctional transporter protein RLIP76 is the primary determinant of the rate of CDE. … …American Journal of Immunology, Vol. 6, Issue 3 · 13 Sep 2010 · 8,095 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSuppression of Basal and Cytokine Induced Expression of MHC, ICAM 1 and B7 Markers on Mouse Lung Epithelial Cells Exposed to Diesel Exhaust ParticlesRajiv K. Saxena, Wanda Williams, M. Ian GilmourDiesel exhaust particles (DEP) constitute a significant component of airborne particulates in urban environment. Exposure to DEP is known to enhance susceptibility to viral and bacterial infections. We hypothesized that DEP could partially exert its effect on disease susceptibility by interfering with antigen presentation required for the generation of protective adaptive immune responses. MHC class I and class II molecules, … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,607 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCiprofloxacin Does Not Exert Nephrotoxicity in RatsAsli Baykal, Figen Sarigül, G Süleymanlar et al.Ciprofloxacin, a member of the fluoroquinolone class, is an antibiotic used as a treatment for infections including the Anthrax bacteria. Studies concerning the safety and efficacy of ciprofloxacin have been controversial with respect to nephrotoxicity. Using rats orally treated with ciprofloxacin (400mg/kg/d), the effects of this drug were analyzed measuring several indications of nephrotoxicity: β-NAG, creatinine, blood urea nitrogen, and … …American Journal of Infectious Diseases, Vol. 1, Issue 3 · 30 Sep 2005 · 7,440 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordLiDAR-Based Obstacle Detection and Avoidance for Navigation and Control of an Unmanned Ground Robot Using Model Predictive ControlSai Charan Dekkata, Sun Yi, M. A. Muktadir, Selorm GarfoUnmanned Ground Vehicles (UGVs) have, as of late, been utilized in a wide assortment of utilizations because of their flexibility, diminished expense, and quick response, among other benefits. Search and Rescue (SAR) is quite possibly the most conspicuous zones for the work of UGVs instead of a monitored mission, mainly due to its impediments on the expenses, human resources, and … …Journal of Mechatronics and Robotics, Vol. 7, Issue 1 · 30 Mar 2023 · 8,213 accessesView PDF Cite