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71 articles for “Variants”

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Research ArticleOpen accessIn the abstractCommon Metamodel of Component Diagram and Feature Diagram in Generative ProgrammingMatija Novak, Ivan Magdalenić, Danijel RadoševićComponent-based software engineering and generative programming are common approaches in software engineering. Each approach has some benefits and domain of usage. Component-based development is used to build autonomous components that can be further combined in different ways, while generative programming is more suitable when building systems that have different variants. Before a variable component based system can be build, it … …Journal of Computer Science, Vol. 12, Issue 10 · 15 Dec 2016 · 7,680 accessesView PDFCite
EditorialOpen accessIn the abstractBig Data and Parkinson’s Disease - from Understanding of Disease to Personalised MedicineYen F. Tai, Nicola PaveseThe advancement of information technology in recent years has generated a huge amount of datasets in all areas of scientific research. This has led to new opportunities to harness the 'Big Data' to improve our understanding of diseases - from investigating disease mechanisms to monitoring treatment responses. The Big Data approach is a data-driven and often hypothesis-free, way of studying … …Neuroscience International, Vol. 7, Issue 1 · 27 Jul 2016 · 7,755 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeurophysiological Mechanisms of Rapidity Quality Development in Female Students Going in for Basketball and Volleyball at Sports ClubsAngelina Shakhanova, Aida Cheuzheva, Ekaterina Kalnaya, Tatiana PetrovaUsing the “NS-Pshykho Test” certified software package (Ivanovo, Russia), we studied the measurements of Simple Hand-Eye Response time (SHER), tapping test frequency, time of Reaction To Moving Object (RMO), Critical Flicker Fusion Frequency (CFFF) in female students going and not going in for sports (volleyball, basketball) at sports clubs. The basis of neuromotor state is formed by variants of classical … …American Journal of Applied Sciences, Vol. 13, Issue 5 · 17 May 2016 · 7,603 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenomic Signature of Respiratory Microbes on Human Scalp EpitheliaBhola Nath Paul, Vani Mishra, Jasmeet Kaur Chhabra, Divyani PaulDespite overlap between habitats occupied by diverse Airborne Respiratory Microbes (ARM), the airway epithelium is known for respiratory microbe infections, human scalp epithelium is undocumented. Analogous to airways epithelium, the scalp epithelium is vulnerable to infection by dormant variants of sensitive microbes that underlie many chronic and relapsing diseases, difficult to eradicate by conventional antibiotics and challenged our ability to … …American Journal of Immunology, Vol. 11, Issue 3 · 11 Sep 2015 · 7,074 accessesView PDFCite
Research ArticleOpen accessIn the abstractProbing the Substrate Specificity and Intersubunit Interactions of Brevundimonas Diminuta Glutaryl Acylase with Site-Directed MutagenesisMichael Eldarov, Anna Lyashenko, Tatyana Sherbakova et al.Glutaryl-7-ACA acylases (GLA) are industrial enzymes widely used for the production of 7-aminocepahlosporanic acid (7-ACA)-the starting compound for manufacturing of semisynthetic cephalosporin antibiotics. Generation of mutant GLA's with increased activity and stability, capability for single-step conversion of cephalosporin C (CPC) directly to 7-ACA is a promising route to improve the current biocatalytic technologies. In this study GLA from Brevundimonas diminuta … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 12 Nov 2014 · 8,160 accessesView PDFCite
Research ArticleOpen accessIn the abstractMOLECULAR CHARACTERIZATION ON THE BASIS OF HA, NA AND M GENE REVEALED CHANGES IN CRITICAL AMINO ACID POSITIONS OF INFLUENZA A (H3N2) VIRUS CIRCULATING IN INDIA DURING 2011-2013Sachin Kumar, Shashi Khare, Bano Saidullah et al.Influenza a (H1N1) virus is responsible for acute respiratory infection in human, which occasionally causes epidemic and rarely a pandemic. Full length DNA sequencing of HA, NA and M gene of H3N2 virus from year 2011-2013 was performed for determination of the circulating strains in India along with monitoring status of various mutations associated with drug resistance and virulence. Genetic … …American Journal of Infectious Diseases, Vol. 10, Issue 3 · 18 Oct 2014 · 6,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Cloning and Heterologous Expression of Human Interferon Alpha2b GeneI. Made Artika, Yemima Budirahardja, Anna Lucia EkowatiHuman alpha Interferons (hIFNα) have been shown to have antiviral, antiproliferative and immunomodulatory activities. The human interferon alpha2b (hIFNα2b), is one of the human interferon alpha2 sub variants, naturally synthesized as a polypeptide of 188 amino acid residues, the first 23 residues of which represents a signal peptide. In the present study, the hIFNα2b gene was expressed after being fused … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,835 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplication of Newton Raphson Algorithm for Optimizing Transmission Control Protocol PerformanceJ. Viji Priya, S. SuppiahWireless networks are growing rapidly. TCP is the most widely-used protocol on Internet and so optimizing TCP performance is very important for fast efficient data transfer. The different existing TCP variants and solutions they have not been analyzed together to identify the bottlenecks in wireless networks. TCP has a major problem in its congestion control algorithm which does not allow … …Journal of Computer Science, Vol. 9, Issue 5 · 20 May 2013 · 6,302 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhanced Ensemble Prediction Algorithms for Detecting Faulty Modules in Object Oriented Systems Using Quality MetricsM. Punithavalli, C. NeelamegamThe high usage of software system poses high quality demand from users, which results in increased software complexity. To address these complexities, software quality engineering methods should be updated accordingly and enhance their quality assuring methods. Fault prediction, a sub-task of SQE, is designed to solve this issue and provide a strategy to identify faulty parts of a program, so … …Journal of Computer Science, Vol. 8, Issue 12 · 20 Dec 2012 · 6,435 accessesView PDFCite
Research ArticleOpen accessIn the abstractBayesian Exploration of Multilocus Interactions on the Genome-Wide ScaleIvan Kozyryev, Jing ZhangProblem statement: Recent technological and scientific advances propelled the field of Genome-Wide Association Study (GWAS), which promises to be instrumental in linking many common complex diseases to their genetic origin. While so far such large-scale surveys have been moderately successful in identifying disease related genetic variants, much of disease heritability is still not accounted for by the discovered loci. There … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 2 Jul 2012 · 7,401 accessesView PDFCite