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Review ArticleOpen accessIn the abstractHost Receptor Immunomodulation in Response to Shigella Surface Antigens: An Insight for Vaccine DevelopmentAshim K. Bagchi, Rushita A. Bagchi, Dipak K. Hens et al.Shigellosis, caused by Shigella is the most common cause of bacillary dysentery. The disease is associated with high morbidity and mortality rate owing to its multiple drug resistance. Hence recovery from the disease would primarily depend on the development of an effective immune-modulator for strong mucosal immune response. The role of cellular immunity may be a critical factor in protection … …American Journal of Immunology, Vol. 11, Issue 2 · 21 Jun 2015 · 6,752 accessesView PDFCite
Review ArticleOpen accessIn the abstractDiagnosis of Pain in Small Companion AnimalsGiorgia della Rocca, Alice Catanzaro, Alessandra Di Salvo, Mary Ellen GoldbergIt is now widely accepted that animals are able to experience pain in a similar way to humans. Acute and/or chronic pain is associated not only with many surgical procedures, but also with various medical diseases, where pain may increase morbidity and mortality. Moreover, some types of pain (e.g., neuropathic pain) can be considered as an illness in themselves. Recognizing … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 15 Jun 2015 · 7,997 accessesView PDFCite
Research ArticleOpen accessIn the abstractMedication Errors: Preventing Untimely DeathsCheryl Ann Alexander, Lidong WangMedication adverse events play a huge role in hospital deaths and morbidity in the US. This plays a large role in the public health of the US at large. Health education is a primary target for those taking medications. A quality assurance or improvement program that is appropriate to capture drug events and measure quality data is essential to prevent … …International Journal of Research in Nursing, Vol. 5, Issue 2 · 19 Jan 2015 · 6,954 accessesView PDFCite
Research ArticleOpen accessIn the abstractANTIOPHIDIAN ACTIVITY OF BROSIMUM GUIANENSE (AUBL) HUBERJose Adolfo Homobono Machado Bittencourt, Nayana Keyla Seabra de Oliveira, Maxwell Santos Cabral et al.Snakebites envenomations are a problem public health in worldwide due to the high rates of morbidity and mortality. The Bothrops venom causes local tissue damage and inflammation is one of the most important events that occur. At present, effective treatment for snakebites is serum therapy with antivenom, which neutralizes systemic alterations but does not prevent local damage that can cause … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 13 May 2014 · 7,784 accessesView PDFCite
Research ArticleOpen accessIn the abstractHISTOPATHOLOGICAL CHANGES IN MICE INFECTED WITH RIVER WATER CONTAMINATED BY PASTEURELLA MULTOCIDA TYPE B:2Mohammed Muqdad Khaleel, Faez Firdaus Jesse Abdullah, Lawan Adamu et al.Haemorrhagic Septicaemia (HS) is a fatal systemic disease of bovines typified by an acute, highly fatal septicaemic disease with high morbidity and mortality. In this study, sixty five adult ICR mice were used for the study. In the first phase, 5 mice each were inoculated with 109 cfu of P. multocida type B:2 through the intraperitoneal route. After development of … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 2 · 28 Mar 2014 · 7,747 accessesView PDFCite
Research ArticleOpen accessIn the abstractPRESUMPTIVE REOVIRUS INFECTION IN BROILER BREEDERSF. A. Moreira, M. L. Pinto, L. Cardoso, A. C. CoelhoTenosynovitis is one of the pathological manifestations of avian reovirus infection and are of economic importance, special in one of the most important stages of the poultry industry, i.e., broiler breeders. In late May 2012, an outbreak of unilateral lameness occurred in a broiler breeder flock (15,000 birds divided by two houses) of a multi-age farm, with a total of … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 1 · 3 Feb 2014 · 7,004 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetection of Antibodies Against Bovine Herpes Virus 1, Bovine Viral Diarrhea Virus and Bovine Respiratory Syncytial Virus in Early and Ultra-Early Weaned Beef CalvesDiego Daniel Gonzalez, Juan Sebastian Vittone, Martin Lado et al.Bovine respiratory disease is the leading cause of morbidity and mortality in weaned calves. In Argentina, two weaning practices have been implemented. In the early weaning, the calf is removed from the cow at 60-70 days of age while in ultra-early weaning the calf is weaned at 30-45 days of age. The purposes of both systems is to improve cow … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 29 Oct 2013 · 8,384 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdaptogenic Potentials of Cyphostemma glaucophilla Aqueous Leaf ExtractOjogbane Eleojo, Nwodo Okwesili Fred Chiletugo, Omale JamesCytophostemma glaucophilla aqueous extract is used in Kogi and Kwara States of Nigeria to treat Kwashiorkor and to boost immunity. As part of the effort to evaluate its effect on stress, it was screened for adaptogenic potentials. This investigation was conducted using albino rats to determine the ability of this plant to increase non specific resistance against physical, biological and … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 7,118 accessesView PDFCite
Research ArticleOpen accessIn the abstractNevirapine Hepatotoxicity: Implications of Risk FactorsElias Adikwu, Oputiri Deo, Oru-Bo Precious Geoffrey, D. Akuegbe EnimeyaHighly active antiretroviral therapy is used in the management of HIV/AIDS; it has contributed tremendously in the reduction of mortality and morbidity rate in HIV patients. Despite the outstanding achievement with the use of HAART its major limitation is toxicity. Among these toxicities is hepatotoxicity which is said to be associated with nevirapine containing highly active antiretroviral therapy. Recent reports … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 3 Jun 2013 · 7,653 accessesView PDFCite
Research ArticleOpen accessIn the abstractChronic Kidney Disease-Mineral Bone Disoder: Fibroblast Growth Factor-23 and Phosphate MetabolismWisit Cheungpasitporn, Pongsathorn Kue-A-Pai, Patompong Ungprasert et al.Chronic Kidney Disease (CKD) is a growing epidemic in the United States. There are hormonal changes that develop long before the mineral changes in patients with CKD occur. Increased Parathyroid Hormone (PTH) levels first become evident when the estimated Glomerular Filtration Rate (eGFR) is below 60 mL/min/1.73m2. High serum phosphate stimulates the secretion of the Fibroblast Growth Factor 23 (FGF-23) … …Current Research in Medicine, Vol. 4, Issue 1 · 4 May 2013 · 6,877 accessesView PDFCite