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212 results for “Liver”
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Research ArticleOpen accessIn the keywordsS-Allyl-Cysteines Reduce Amelioration of Aluminum Induced Toxicity in RatsSadhana ShrivastavaProblem statement: Aluminum (Al) is a trivalent cation found in its ionic form in most kinds of animal tissues and in natural waters everywhere. Approach: It is a potent neurotoxin and has been associated in the pathogenesis of several clinical disorders including Alzheimer’s disease. Results: The aim of the study was to demonstrate the protective effect of S-Allyl-Cysteines (SAC) against … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,748 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEvidences of Hepatitis C Virus Replication in Hepatocytes and Peripheral Blood Monocuclear Cells from Patients Negative for Viral RNA in SerumViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.In this study, we examined the expression of hepatitis C virus (HCV) components in hepatocytes and peripheral blood mononuclear cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA. The samples obtained from 25 randomly selected patients (13 of 25 patients showed no histological evidences of chronic hepatitis and had normal serum ALAT and GGTP levels) were … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 7,164 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDetection of HCV Components and Pathological Reactions in Apoptotic Hepatocytes from Chronically HCV-infected PatientsViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Analysis of Hepatitis C Virus (HCV)-infected hepatocytes at the cellular level may contribute to elucidate the mechanisms of HCV pathogenesis. In this work, the presence of HCV components and pathological reactions in apoptotic hepatocytes from chronic HCV-infected patients were studied by electron microscopy and confocal microscopy. Eight samples of liver biopsies from patients with chronic hepatitis C were studied by … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,907 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHepatotoxicity Due to Histamine Trifluoro-Methyl Toluidide, Amthamine, R-(-)-α-Methyl Histamine and Clobenpropit (H1R-H4R-Agonists, Respectively) in Rabbit Experimental ModelTrivendra Tripathi, Aijaz Ahmed Khan, Mohammad Shahid et al.Problem statement: Since in vivo studies looking for toxicological impact of histamine receptors-agonists in experimental models are fragmentary, the present study was designed to delineate the histopathological and biochemical changes in livers of rabbits treated with histamine receptors (H1R-H4R)-agonists. Approach: The cohort comprised of six groups (Group I control and Group II-VI treated) containing five rabbits each. Control-group received vehicle … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 8,899 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDirect Acting Anti-Viral Drugs Improve Health-Related Quality of Life in Patients' with Hepatitis CWesam Morad, Warda Othman, Esam Elshimi, Nashwa SheblChronic hepatitis C Virus (HCV) causes significant decline in the Health Related Quality of Life (HRQL). Recently, direct Acting Anti-viral Drugs (DAA) have been endorsed as standard of care for treatment for HCV. To study the HRQL in patients with HCV and cirrhosis before and after DAA. Study design: Prospective cohort hospital based study. We included 500 patients with HCV … …American Journal of Infectious Diseases, Vol. 16, Issue 2 · 29 Apr 2020 · 7,145 accessesView PDFCite
Research ArticleOpen accessIn the keywordsExogenous Pyocyanin Alters Pseudomonas aeruginosa Susceptibility to CiprofloxacinGary D. Grant, Tian Tian Zhang, Lee S. Gloyne et al.This in vitro cell-based study identified the contributing role of pyocyanin in the resistance of Pseudomonas aeruginosa to ciprofloxacin. Problem statement: P. aeruginosa is the major pathogen in the Cystic Fibrosis (CF) lung with pyocyanin being a critical component of its virulence. Prevalence is high and, once acquired, chronic infection is difficult to eliminate. Ciprofloxacin remains a crucial oral agent … …Current Research in Microbiology, Vol. 1, Issue 1 · 30 Jun 2010 · 8,792 accessesView PDFCite
Research ArticleOpen accessIn the author namesA Typology to Describe School Choice Policy in the United States: Using Cluster Analysis to Categorize States’ Charter School Law CharacteristicsWilliam Dabney, Bret Blackmon, Michelle M. LivermorePersistent educational inequality in the United States has inspired various school reform efforts with states adopting a wide variety of charter school laws. This study developed a typology of state-level charter school laws. U.S. states (N = 50) were described and categorized based on characteristics of their charter school laws related to autonomy, funding equity and growth. Autonomy referred to … …Journal of Social Sciences, Vol. 17, Issue 1 · 19 May 2021 · 7,058 accessesView PDFCite
Research ArticleOpen accessIn the author namesJuvenile Court Dispositions in the Deep South: Examining the Concept of Justice by GeographyBret Blackmon, Daphne S. Cain, Michelle LivermoreThe concept of justice by geography suggests that sentencing decisions in the juvenile justice system are influenced by the geographical context of the courts. This study sought to examine this phenomenon by examining rates of harsh juvenile sentencing (dispositions) in 64 parishes (i.e., counties) in the Deep South using parish-level characteristics such as geographic location (urban/suburban vs. rural), race and … …Journal of Social Sciences, Vol. 11, Issue 2 · 30 Jun 2015 · 7,250 accessesView PDFCite
Research ArticleOpen accessIn the abstractCA-LIME: A Collinearity-Aware LIME Framework for Reliable and Interpretable Explanations in Healthcare AIIdris Khan, Sachin BhoiteIn clinical tabular models, correlated biomarkers can make local explanations unstable even when predictive performance appears acceptable. This paper presents CA-LIME, a collinearity-aware extension of LIME built to address that failure mode directly. Five variations of CA-LIME Vanilla reference, VIF, PCA back projection, Ridge, and ElasticNet allow us to investigate how various correlation-control strategies alter explanation behavior. ILPD, Kaggle liver, … …Journal of Computer Science, Vol. 22, Issue 7 · 28 Jul 2026 · 806 accessesView PDFCite
Research ArticleOpen accessIn the abstractAluminium-Induced Hepatotoxicity and the Protective Role of Withania somnifera (Ashwagandha) in Wistar RatsAnchana Babu, Rekha D Kini, Nayanatara Arun Kumar, Megha GokulAluminium is a widely distributed environmental contaminant whose chronic exposure leads to accumulation in multiple organs, including the liver, resulting in oxidative stress and tissue damage. When reactive oxygen species production exceeds the body's antioxidant defense capacity, cellular injury ensues — a mechanism central to aluminium-induced hepatotoxicity. Withania somnifera (Ashwagandha), an evergreen herb of the Solanaceae family widely cultivated in … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 6 Apr 2026 · 1,449 accessesView PDFCite