Review ArticleOpen accessIn the abstractJAK Inhibitors for Rheumatoid Arthritis: Assessing Efficacy and Safety in TreatmentAnastasia V. Poznyak, Varvara A Orekhova, Natalia Vladimirovna Elizova et al.Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, progressive joint destruction, and systemic complications. Dysregulated cytokine signaling through the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway plays a central role in RA pathogenesis, making JAK inhibitors an important therapeutic option. Tofacitinib, baricitinib, and upadacitinib are oral targeted synthetic disease-modifying antirheumatic drugs that interfere with … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 8 Oct 2026 · 430 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlternative Monitoring Approach for IPTVAngel Ignatov, Hristo Toshkov Hristov, Jan Latal et al.IPTV emerged in the late 1990s as a solution for delivering Video on Demand (VoD) and live television over managed networks. Its widespread adoption accelerated after the expansion of broadband internet and the introduction of web technologies such as HTML5 and adaptive streaming protocols (MPEG-DASH and HLS), which enabled television content to be streamed directly through web browsers. Across Europe, … …Journal of Computer Science, Vol. 22, Issue 11 · 8 Oct 2026 · 438 accessesView PDFCite
Research ArticleOpen accessIn the abstractRIA-ViT: A Residual Inception Atrous Vision Transformer for Detection of Gallbladder Cancer from CT ImagesAbhishek Sehrawat, Anita Gupta, Vishnupriya, Varun P. GopiGallbladder Cancer (GBC) is a rare but highly aggressive malignancy of the biliary system. In early-stage gallbladder cancer, there are neither overt symptoms nor specific signs. In most patients, it is diagnosed late, resulting in poor outcomes. Even when imaging is available, diagnosing GBC remains difficult because its features overlap with those of non-neoplastic gallbladder pathologies. Furthermore, the overlap between … …Journal of Computer Science, Vol. 22, Issue 10 · 6 Oct 2026 · 423 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of Crop Yield Detection and Prediction With Multimodal Data Using Fusion TechniquesKutlwano Sedimo, Rajalakshmi Selveraj, Venumadhav Kuthadi, Thulaganyo DimakatsoMost often, soil, environmental, and agronomic data are used in pieces, hence limiting the performance of crop selection and yield forecasting. This study develops an integrated, fusion-based framework that combines soil image classification, environmental feature analysis, and input-driven yield prediction to support precise agricultural decision-making. The system consists of three major modules: (i) a CNN for the classification of soil … …Journal of Computer Science, Vol. 22, Issue 10 · 5 Oct 2026 · 494 accessesView PDFCite
Research ArticleOpen accessIn the abstractBenchmarking Lightweight Deep Learning Models for Field Based Sorghum Leaf Disease DetectionPrince Daughin Ngqabutho NcubeSorghum is a climate-resilient cereal crop central to food and livelihood security across Southern Africa, yet its productivity is frequently reduced by foliar diseases that smallholder farmers struggle to diagnose reliably in the field. While deep learning has demonstrated strong potential for automated plant disease identification, sorghum remains underrepresented in the literature, and no prior study has provided a comprehensive, … …Journal of Computer Science, Vol. 22, Issue 10 · 29 Sep 2026 · 548 accessesView PDFCite
Research ArticleOpen accessIn the abstractTAGN-IDC: Implicit Discrete Constraints for Tsunami Aware Graph Neural Networks in Spatial Evacuation RoutingSularno, Wendi Boy, Putri Anggraini et al.Tsunami evacuation route requires rapid identification of safe evacuation paths under dynamically changing hazard conditions. A major challenge is incorporating hard binary road-blockage constraints caused by tsunami inundation while maintaining end-to-end differentiability for deep learning models. Existing approaches commonly rely on continuous relaxations or stochastic sampling techniques, which either compromise physical feasibility or increase computational complexity. This study proposes the … …Journal of Computer Science, Vol. 22, Issue 9 · 24 Sep 2026 · 711 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Water Bath Heating on Tannin Content and Quality Improvement Potential of Gambier (Uncaria gambir Roxb.)Daimon Syukri, Bastian Nova, Rina Yenrina et al.Gambir (Uncaria gambir Roxb.) is a source of natural phenolic compounds rich in catechins and tannins and has potential as a sustainable industrial raw material. During heating, phenolic compounds may undergo structural changes, including possible oxidation and polymerization, which can affect gambier quality beyond its catechin content. This study evaluated the effect of indirect heating duration using a water bath … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 23 Sep 2026 · 715 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlpha Thalassemia Carrier Detection a Diagnostic ApproachH. R. Samruddhi, Anupama Hegde, Harsha Prasada L et al.Alpha-thalassemia is one of the most common single-gene disorders, and its carrier state often remains undetected due to nonspecific hematological findings. This study aimed to identify alpha-thalassemia carrier status among people being investigated for hemoglobinopathy in a tertiary care setting. A cross-sectional laboratory-based study was conducted from January 2023 to January 2024. Hemoglobin variant analysis reports by High Performance Liquid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 22 Sep 2026 · 492 accessesView PDFCite
Review ArticleOpen accessIn the abstractMultidrug Resistant Microorganisms (MDR) and Biofilm Producers: A Challenge for Hospital Infectious ControlDaniel Lucio, Elizabeth Proaño, Alberto Bustillos et al.Antimicrobial Resistance (AMR) now represents a major threat to contemporary health care, especially in hospitals, where repeated antimicrobial exposure selects for and facilitates the dissemination of Multidrug-Resistant (MDR) microorganisms. Biofilm growth adds another layer of persistence by increasing microbial tolerance, supporting long-term colonization of medical devices, and worsening clinical and economic outcomes. This narrative review synthesizes evidence on MDR biofilm-forming … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 12 Sep 2026 · 791 accessesView PDFCite
Research ArticleOpen accessIn the abstractPromising Biocontrol Agents Against the Main Pathogens of Apple Fruit RotElvira Ismailova, Nurlan Kuldybayev, Gul Baimakhanova et al.Current study looked into how well microorganisms, both those already known and newly found, from the surface of plants in gardens in southern and southeastern Kazakhstan could fight against other harmful microbes. We evaluated the effectiveness of 16 strains of lactic acid bacteria, 11 strains from the Bacillus and Pseudomonas genera, and 7 strains of Trichoderma fungi (all sourced from … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 25 Aug 2026 · 868 accessesView PDFCite