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63 articles for “Heterogeneity”

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Research ArticleOpen accessIn the abstractRADIOSENSITIZATION OF CANCER STEM CELLS: TARGETING TGFβ, NOTCH OR TELOMERASE TO IMPROVE TUMOR RESPONSE O RADIOTHERAPYIgnacio Fernandez-GarciaRadiation resistant cancer stem cells are the main reason for treatment failure and tumor recurrence after cancer radiotherapy. Increasing biological evidences demonstrate that these cells possess the capacity to repair radiation induced DNA damage, protect themselves from radiation derived reactive oxygen species, survive and proliferate after several fractions of radiotherapy and finally, repopulate the heterogeneity of the tumor. Thus, targeting … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Jul 2014 · 7,459 accessesView PDFCite
Research ArticleOpen accessIn the abstractATRA AS A POTENTIAL ANTIMETASTATIC AGENT IN COLORECTAL ADENOCARCINOMARobert Edwards, Kambiz Afrasiabi, Kehui WangThe family of Retinoic acid compounds have long been the subject of intense study and interest as chemo prophylactic agents. This dates back to their therapeutic effect in leukoplakia Where ATRA was shown to lead to the reversal of premalignant lesions and Subsequent reports on their use in metastatic colorectal adenocarcinoma and a vast array of other malignant disorders as … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 26 Mar 2014 · 7,344 accessesView PDFCite
Research ArticleOpen accessIn the abstractIMPROVING FAULT TOLERANT RESOURCE OPTIMIZED AWARE JOB SCHEDULING FOR GRID COMPUTINGK. Nirmala Devi, A. TamilarasiWorkflow brokers of existing Grid Scheduling Systems are lack of cooperation mechanism which causes inefficient schedules of application distributed resources and it also worsens the utilization of various resources including network bandwidth and computational cycles. Furthermore considering the literature, all of these existing brokering systems primarily evolved around models of centralized hierarchical or client/server. In such models, vital responsibility such … …Journal of Computer Science, Vol. 10, Issue 5 · 4 Jan 2014 · 6,896 accessesView PDFCite
Research ArticleOpen accessIn the abstractTasks Scheduling using Ant Colony OptimizationA. P. Shanthi, G. Umarani Srikanth, V. Uma Maheswari, Arul SiromoneyProblem statement: Efficient scheduling of the tasks to heterogeneous processors for any application is critical in order to achieve high performance. Finding a feasible schedule for a given task set to a set of heterogeneous processors without exceeding the capacity of the processors, in general, is NP-Hard. Even if there are many conventional approaches available, people have been looking at … …Journal of Computer Science, Vol. 8, Issue 8 · 25 Jul 2012 · 7,668 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnergy Efficient Aggregation for Continuous Monitoring Applications of Wireless Sensor NetworkR. Rajkamal, P. Vanaja RanjanProblem statement: Continuous Monitoring of time critical phenomenon is one of the major streams of possible application in this arena. Sensing and Monitoring of such phenomenon involves in dealing with large amount of data correlated in spatial and temporal dimensions. Most applications of WSN, the nodes are hard to reach and it is impossible to replace their batteries so the … …Journal of Computer Science, Vol. 8, Issue 1 · 28 Oct 2011 · 7,401 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Discrete Event Simulation Framework for Utility Accrual Scheduling Algorithm in Uniprocessor EnvironmentIdawaty Ahmad, Shamala Subramaniam, Mohamed Othman, Zuriati ZulkarnainProblem statement: The heterogeneity in the choice of simulation platforms for real time scheduling stands behind the difficulty of developing a common simulation environment. A Discrete Event Simulation (DES) for a real time scheduling domain encompassing event definition, time advancing mechanism and scheduler has yet to be developed. Approach: The study focused on the proposed and the development of an … …Journal of Computer Science, Vol. 7, Issue 8 · 14 Jul 2011 · 7,224 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunodeficiency Provides Partial Protection from Bone Loss Induced by Castration and OvariectomyCedo M. Bagi, Edwin Berryman, Nels Hanson et al.Problem Statement: The interaction of osteoblasts and osteoclasts with cells of the immune system has been suggested as a contributing factor in the development of osteoporoses. Evidence from studies in rodents suggests that T cells play a significant role in bone loss following estrogen deficiency. The goal of this study was to investigate whether the lack of functional T cells … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,074 accessesView PDFCite
Research ArticleOpen accessIn the abstractObject Based Middleware for Grid ComputingS. Muruganantham, P. K. Srivastha, KhanaaProblem statement: "Grid" computing has emerged as an important new field, distinguished from conventional distributed computing by its focus on large-scale resource sharing, innovative applications and, in some cases, high-performance orientation. The role of middleware is to ease the task of designing, programming and managing distributed applications by providing a simple, consistent and integrated distributed programming environment. Essentially, middleware is … …Journal of Computer Science, Vol. 6, Issue 3 · 31 Mar 2010 · 7,339 accessesView PDFCite
Research ArticleOpen accessIn the abstractLoad Allocation Model for Scheduling Divisible Data Grid ApplicationsMonir Abdullah, Mohamed Othman, Hamidah Ibrahim, Shamala SubramaniamProblem statement: In many data grid applications, data can be decomposed into multiple independent sub-datasets and distributed for parallel execution and analysis. Approach: This property had been successfully employed by using Divisible Load Theory (DLT), which had been proved as a powerful tool for modeling divisible load problems in data-intensive grid. Results: There were some scheduling models had been studied … …Journal of Computer Science, Vol. 5, Issue 10 · 31 Oct 2009 · 6,900 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Characterization of Opium Poppy (Papaver somniferum) GermplasmHari Shanker Acharya, Vimal SharmaProblem statement: The medicinal value of opium poppy (2n = 22, Papaver somniferum L.) is due to presence of more than two dozen alkaloids. The genetic origin and diversity of cultivars used in the breeding collection is not fully known. To evaluate the genetic diversity of the 24 germplasm currently cultivated in the state to provide genetic information about heterogeneity, … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,096 accessesView PDFCite