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84 results for “HIV Infection”

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Research ArticleOpen accessIn the abstractComparison of Tuberculin Skin Test and Interferon Gamma Assay for the Diagnosis Latent TuberculosisAbolfazl Poorhasan, Mehdi Haghdoost, Omid MashrabiProblem statement: After HIV infection, TB is the most common cause of mortality due to a single infectious agent. Until 1985, tuberculosis cases in the world were decreasing every year, but then with the prevalence of HIV infection, TB cases are increasing every year. Obviously, with this prevalence of tuberculosis, the best way to control it is to track the … …American Journal of Infectious Diseases, Vol. 6, Issue 2 · 30 Jun 2010 · 7,311 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction and Roles of Glial Tissue Inhibitor of Metalloproteinases-1 in Human Immunodeficiency Virus-1-Associated Dementia Neuroinflammation: A ReviewC. Chao, A. GhorpadeProblem statement: Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and its cognate targets, the Matrix Metalloproteinases (MMPs), were differentially expressed in human brain samples with or without HIV-1 infection or HIV-1 Encephalitis (HIVE). Approach: A through literature review demonstrated that cell culture models of Central Nervous System (CNS) cell types had been used to illustrate the intricate temporal patterns of TIMP-1/MMP expression, … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 6,957 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A ReviewBryan P. Irish, Zafar K. Khan, Pooja Jain et al.Problem statement: Infection with retroviruses such as human immunodeficiency virus type 1 (HIV-1) and human T cell leukemia virus type 1 (HTLV-1) have been shown to lead to neurodegenerative diseases such as HIV-associated dementia (HAD) or neuroAIDS and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP), respectively. Approach: HIV-1-induced neurologic disease is associated with an influx of HIV-infected monocytic cells across the blood-brain … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 14,895 accessesView PDFCite
Research ArticleOpen accessIn the abstractPassive Transfer of HIV-1 Antibodies and Drug Resistant Virus during a Health Care Worker Accident: Implications for HCW Post-Exposure ManagementCarlos Fernando De Oliveira, Ricardo Sobhie Diaz, Abdallah Harmache et al.Problem statement: We studied in detail a case in which a nurse caring for an HIV-infected child suffered a deep-laceration accident with contaminated blood. Approach: The patient had been treated with zidovudine (ZDV) and the nurse became infected despite prophylactic use of ZDV initiated 2 h after the accident. A reactive anti-HIV-1/2 EIA and an indeterminate western blot (gp120/160 reactivity) … …American Journal of Infectious Diseases, Vol. 4, Issue 4 · 31 Dec 2008 · 6,876 accessesView PDFCite
Research ArticleOpen accessIn the abstractRetinoids and Opioids: Factors in the Development of HIV-Related Neurological DiseaseWalter Royal, III, Joseph L. BryantNeurological disease occurs frequently in HIV-infected individuals and may occur at even higher rates among infected drug users. Among the potential mechanisms that promote such impairment, retinoid deficiency may have selective effects that could both lead to alterations in immune function and enhanced replication of HIV. Studies are currently underway to examine the possible selective effects of retinoid receptor activation … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 6,768 accessesView PDFCite
Research ArticleOpen accessIn the abstractMethamphetamine Inhibits β-Chemokines and Co-Stimulatory Molecule Expression by Dendritic CellsMadhavan P.N. Nair, Jose W. Rodriguez, Irina M. Borodowsky et al.The US is currently experiencing a serious epidemic of methamphetamine (Meth) use entangled with HIV-1 infection. Blood monocyte derived dendritic cells (DC ) are the first line of defense against HIV-1 infection and are the initial target of HIV-1 in injection drug users. Chemokines are known to be HIV-1 suppressing molecules and are positively associated with non- progression of HIV … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,546 accessesView PDFCite
Research ArticleOpen accessIn the abstractCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,016 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunodeficient Parameters in the HIV-1 Transgenic Rat ModelSulie L. Chang, Frank Ocasio, Jose A. BeltranRecently an HIV-1 transgenic (HIV-1Tg) rat model was created that carries a gag-pol-deleted HIV-1 genome under the control of the HIV-1 viral promoter. However, other viral proteins are expressed in most organs and tissues, and are found in the circulating blood. Since HIV-1 targets the immune system in humans, we examined two immunological parameters, leukocyte-endothelial adhesion (LEA) and inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractHIV/AIDS Prevention Knowledge among Youth in Cape Town, South AfricaKermyt G. Anderson, Ann M. BeutelHIV/AIDS knowledge is an important component of HIV/AIDS risk prevention strategies that may influence engagement in high risk behavior. This paper examines HIV/AIDS prevention knowledge among a representative sample of 4,174 youth living in Cape Town, South Africa. Data come from the Cape Area Panel Study (CAPS), and include black, coloured, and white respondents ages 14-22. Using an open-ended question, … …Journal of Social Sciences, Vol. 3, Issue 3 · 30 Sep 2007 · 9,224 accessesView PDFCite
Research ArticleOpen accessIn the abstractConsequence on Treatment of TB Patients Affected by HIV/AIDS A Conceptual ResearchSarder N. Uddin, S. J. Hossain, Md. N. Huda et al.Mycobacterium tuberculosis is an ancient malady, which is one of the world’s most wide spread infectious bacterial agents. Fully one-third of the world’s population is already infected with Mycobacterium tuberculosis, with the greatest burden of disease and infection borne by people in developing countries. Tuberculosis disease is still out of control. Alarming spread of Human Immunodeficiency Virus (HIV) and emergence … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 7,023 accessesView PDFCite