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65 articles for “Genetic Parameters”
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Research ArticleOpen accessIn the abstractCASE REPORT OF A PATIENT WITH RARE P.ARG136CYS (APOE2*) MUTATION IN APOLIPOPROTEIN E GENEJana Lisyova, Jan Chandoga, Stanislav Oravec et al.Apolipoprotein E (apoE) is a polymorphic glycoprotein associated with plasma lipoproteins and plays an essential role in the metabolism and clearance of plasma lipids. ApoE can represent the major genetic risk factor in development of premature atherosclerosis, coronary heart disease and late-onset familial and sporadic Alzheimer’s Disease (AD). We present a case report of a 51-year old male with suspected … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 9 Jan 2014 · 7,297 accessesView PDFCite
Research ArticleOpen accessIn the abstractGeometric Optimization of Three-Phalanx Prosthesis Underactuated Fingers using Particles Swarm AlgorithmSomar M. Nacy, Shaker S. Hassan, Sadeq Hussein BakhyProblem statement: One are now interested to investigate the optimum design procedure for a finger driving mechanism to have a good configuration of the finger for its utilization in hand prosthesis. A Geometric Optimization of Three-Phalanx Prosthesis Underactuated Fingers (TPPUF) based on a Particle Swarm Optimization (PSO) was presented. Approach: Firstly, a numerical evaluation of the human-like motion was obtained … …American Journal of Engineering and Applied Sciences, Vol. 2, Issue 2 · 30 Jun 2009 · 7,706 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Method for Optimal Location and Expansion of Subtransmission Substations Considering Existing Medium-Voltage Distribution FeedersM. Farrokhifar, M. Bana Sharifian, R. EsmaeilzadehThis research presents an accurate comprehensive cost function for the problem of optimal location of subtransmission substations. Technical constraints and economical parameters are investigated in the modeling. Genetic algorithm is used to optimize the cost function. Coding of decision variables is done in a way that finding the correct solutions is achieved faster. For the first time in this study, … …American Journal of Applied Sciences, Vol. 6, Issue 3 · 31 Mar 2009 · 7,793 accessesView PDFCite
Research ArticleOpen accessIn the abstractGlutathione S-transferase (T1 & M1) Null Genotypes as Risk Determinants in Sudanese for Developing Type Two Diabetes MellitusGaafar Mahmoud, Hisham Mohamed Abdelrahim, Abed Al Salam Aljahmany, Eltayeb Mohamed Ahmed TayrabGlutathione S-transferases (GSTT1 and GSTM1) are globular proteins responsible for the detoxification of xenobiotics and the prevention of oxidative damage. Functional polymorphisms of the antioxidant glutathione and enzymes have a role in the pathogenicity of T2DM and its complications. The present study is aimed to assess association between GSTM1 and GSTT1 genetic polymorphisms with T2DM in Sudanese people. This case-control … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 16 Oct 2020 · 6,426 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessing the Applicability of Landslide Databases for Hazard Management Using Objective and Subjective Models: Australian Geoinformatic CaseM. OwneghProblem statement: In order to assess the applicability of Australian landslide databases as a hazard management support system, current hard and soft literature and data sources were screened. This assessment resulted in the selection of four main data bases including national landslide database (A), Peril Aus ІІ (B), the Cities project (C) and analytical study of Fell (D). Approach: In … …Current Research in Geoscience, Vol. 1, Issue 1 · 30 Jun 2010 · 10,356 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Dynamics Studies of Human β-GlucuronidaseIbrahim Ali Noorbatcha, Ayesha Masrur Khan, Hamzah Mohd SallehProblem statement: The enzyme β-glucuronidase is being used as a reporter molecule in the area of genetic engineering, as a component of prodrug therapy in cancer treatment and in the scouring process of cotton fabrics. However, a detailed understanding of the factors responsible for the stability and the activity of this enzyme is still not available. Molecular Dynamics (MD) simulations … …American Journal of Applied Sciences, Vol. 7, Issue 6 · 30 Jun 2010 · 7,619 accessesView PDFCite
Research ArticleOpen accessIn the abstractDecentralized Controller Design for Static Synchronous Compensator Using Robust Quantitative Feedback Theory MethodSeyed Abbas Taher, Reza Hematti, Ali Abdolalipour, Majid NematiThe Static Synchronous Compensator (STATCOM) provides shunt compensation in similar way to the Static VAR Compensator (SVC) but utilizes a voltage source converter rather than capacitors and reactor. In practice systems use simple Proportional-Integral (PI) controllers for control of STATCOM. However, since the PI control parameters were usually tuned based on classical or trial-and-error approaches, they were incapable of obtaining … …American Journal of Engineering and Applied Sciences, Vol. 1, Issue 1 · 31 Mar 2008 · 7,461 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeveloping an Integrated Method for Optimal Design of Chilled Water Plants in HVAC SystemsNabil Nassif, Nihal Al Raees, Fouad Al Rifaie, Taher Abu-LebdehBuildings account for a large portion of energy use in the US. Many those buildings have equipped with central plants to produce chilled water supplied to central air handling units. The chilled water plant design can have a significant impact on building energy uses and costs. In this paper, an integrated method for optimal design of chilled water plants is … …Energy Research Journal, Vol. 9, Issue 1 · 6 Feb 2019 · 6,592 accessesView PDFCite
InvestigationOpen accessIn the abstractMorphogenetic and Biochemical Study on University Common Bean CollectionBeibitgul Zhumabaeva, Erika Dzhangalina, Zaure Aytasheva et al.This research has been conducted to reveal the outcomes of rotation of crops in mountain and steppe districts near Almaty. The main morphogenetic characteristics have been investigated for the collection of representatives of common bean, Phaseolus vulgaris L. by using samples from various countries such as Kazakhstan, USA, China, Czech Republic, Poland, Turkey and Russia under different climate and soil … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 28 Nov 2017 · 7,051 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,740 accessesView PDFCite