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92 results for “Drug-Resistance”

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Research ArticleOpen accessIn the abstractSYNERGY OF A NOVEL ANTIBIOTIC ADJUVANT ENTITY AGAINST MULTI DRUG RESISTANT ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiIn the present investigation, we investigated the in vitro interaction of ceftriaxone plus sulbactam with disodium edetate, a Non Antibiotic Adjuvant (NAA) against selected clinical isolates and in vitro susceptibility studies were also performed. The isolates were tested against a range of ratios of ceftriaxone and sulbactam using a microdilution checkerboard method. Having determined the appropriate ratios of ceftriaxone plus … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 1 Nov 2013 · 7,419 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of Heterogeneous Glycopeptide Intermediate Resistance in Methicillin-Resistant Staphylococcus aureusManu Chaudhary, Anurag PayasiMultidrug resistant Methicillin-Resistant Staphylococcus Aureus (MRSA) is a major cause of nosocomial and community acquired infections and is on the rise. The aim of this investigation was to explore the prevalence of MRSA and heterogeneous Glycopeptide Intermediate Staphylococcus Aureus (hGISA) in various clinical samples, to investigate the various antibiotic resistant determinant genes among these strains collected from north and west … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 4 Sep 2013 · 7,203 accessesView PDFCite
Research ArticleOpen accessIn the abstractStaphylococcus aureus Nasal Carriage Among Injecting and Non-Injecting Drug Users and Antimicrobial SusceptibilityMojtaba Varshochi, Zahra Attari, Alka Hasani, Ali SeidiStaphylococcus Aureus (SA) is one of the most prevalent bacterial pathogens in human beings. Approximately 20% of healthy persons are persistent carriers and 60% are intermittent carriers of SA. Nasal cavity is one of the most important sites of its colonization. Intravenous (IV) drug abuse has been proposed as a risk factor for colonization of SA in the nasal mucosa. … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 23 May 2013 · 7,315 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Self-Medication Among Pharmacy StudentsRiham Waisi, Laila Mouslli, Osama Hussein Mohamed Ibrahim, Suleiman Ibrahim SharifTo determine the incidence of self-medication among Sharjah university students and the impact of medical knowledge on such practice. A pre-validated questionnaire was distributed to 200 pharmacy students during May, 2012. Data were analyzed using SPSS and results expressed as counts and percentages. The overall response rate was 85% with 98% of respondents being Arabs. Females comprised about 91% of … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 4 · 15 Dec 2012 · 10,379 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of Drug-Resistant Strains of Streptococcus Pneumoniae in AbakalikiIroha Ifeanyichukwu Romanus, Okafor Florence Njideka, Nwakaeze Emmanuel Amobi et al.Streptococcus pneumoniae is a major cause of illness such as pneumonia, meningitis, bacteremia and otitis media in children and the elderly. The emergence of drug-resistant strains threatens to complicate the management of these diseases. We conducted a hospital-based surveillance for drug-resistant Strep. Pneumoniae in outpatients with pneumococcal infection in Abakaliki Ebonyi State Nigeria. Between 2003-2005 from January through December, a … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 26 Nov 2012 · 7,680 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeveloping a System for Antibacterial Treatment of Dental Caries using Culture Based ApproachM. Mishra, S. Ghosh, L. E. Alex et al.Problem statement: Dental caries is a chronic disease worldwide, caused mainly by microbes. The orthograde approaches still remain the only option of treatment. Lack of rapid antibiotic sensitivity determination of the dental pathogen is a rate limiting step in the field of Dental Microbiology. Approach: The culture dependent analysis was used for the study of oral microflora from five healthy … …OnLine Journal of Biological Sciences, Vol. 12, Issue 2 · 18 May 2012 · 9,064 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Sensitivity Pattern of Blood Isolates of Acinetobacter Species in a Tertiary Care Hospital: A Retrospective AnalysisP. S. Shareek, D. Sureshkumar, Ramgopalakrishnan et al.Problem statement: Multi-drug resistant Acinetobacter bacterium is one of the major causes of sepsis in ICUs in tertiary care hospitals in India. In this report we describe the antibiotic sensitivity patterns of Acinetobacter species isolated from blood over a one year period at a tertiary care hospital. Approach: We retrospectively analyzed the sensitivity pattern of Acinetobacter species isolated from blood … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 24 Mar 2012 · 8,570 accessesView PDFCite
Research ArticleOpen accessIn the abstractUse of Enterobacterial Repetitive Intergenic Consensus PCR in Detecting Target(s) of Hapalindole-T, From a Cyanobacterium, in Escherichia Coli: In Silico ValidationManoj K. Tripathi, Maheep Kumar, Vinay K. Singh et al.Problem statement: Identification of newer biomolecule as well as targets are a rising concern because of increasing drug resistance in bacteria. We have isolated a broad spectrum antibiotic biomolecule Hapalindole-T from a cyanobacterium, Fisherella sp. growing on local Azadirachta indica tree bark. A model bacterium E. coli was screened spontaneously for Hap-T resistance. These resistant strains of E. coli were … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 3 Mar 2012 · 13,780 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy on Survival of Chlamydia trachomatis in the Presence of Antichlamydial DrugsApurb Rashmi Bhengraj, Pragya Srivastava, Harsh Vardhan et al.Problem statement: Recurrent genital Chlamydia trachomatis infections due to treatment failures may results in complex sequelae leading to reproductive complexity and morbidity. It can be resulted by the heterotypic resistance with decreased drug susceptibility characteristic of the isolate. Studies are needed to understand the treatment failures and resistance characteristic of C. trachomatis. Hence, in vitro study was conducted on C. … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 20 Feb 2012 · 7,774 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficient Anaerobic Fermentation of Simple Sugars by Yeast Fuels Resistance Candida spp. Infections to Eradication by DrugsNedosa Ikenna Valentine, Utoh-Nedosa Uchechukwu Anastasia, Dan Danjuma et al.Problem statement: Human systemic Candida infections had proved difficult to eradicate by the medical health care system. Some practitioners and scholars see the problem as being due to drug resistance. For example an author wrote that ‘secondary drug resistance is clearly being encountered in one setting, oropharyngeal candidiasis in patients with advanced Human Immunodeficiency Virus type 1 (HIV-1) infection usually … …American Journal of Infectious Diseases, Vol. 7, Issue 4 · 10 Dec 2011 · 7,840 accessesView PDFCite