66 articles for “Clinical Practice”

Research ArticleOpen accessIn the abstractU.S. Malpractice in Internal Medicine: Closed Claim Cases as Tools for Identification, Teaching and PreventionKimberly Ku, Theresa Vettese, Diane LevineMedical malpractice litigation as a system in the U.S. serves multiple goals, including the promotion of safer medicine and the compensation of wrongfully injured patients. However, these aims are often at odds with systems-oriented strategies needed to promote patient safety. Additionally, there is widespread doubt of the actual fairness and efficiency of malpractice litigation. Regardless of the details surrounding major … …Current Research in Medicine, Vol. 4, Issue 2 · 4 Sep 2013 · 6,989 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMirtazapine in Veterinary Medicine a Pharmacological Rationale for its Application in Chronic PainMario Giorgi, Helen OwenProblem statement: Many recent studies have shown that antidepressant agents have analgesic effects in addition to their intended primary actions. The Tricyclic Antidepressants (TCAs) have been recognized as an effective first-line treatment of human neuropathic pain but unfortunately they display a wide range of side effects. Recent studies have shown that Selective Serotonin Reuptake Inhibitors (SSRI) also have potential analgesic … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 19 May 2012 · 8,189 accessesView PDF Cite

Research ArticleOpen accessIn the abstractStrains of Klebsiella Pneumoniae from Intensive Care Unit Producing CTX-M-15 Extended Spectrum Beta LactamasesI.R. Iroha, A.E. Oji, A.E. Nwakaeze et al.Problem statement: Resistance to third generation cephalosporins due to acquisition and expression of Extended Spectrum β-Lactamase (ESBL) among Gram-negative bacteria is on the increase. Infections involving extended spectrum beta lactamase bacteria are associated with significant morbidity and mortality. Therefore, infections due to ESBL isolates continue to pose a serious challenge to infection management worldwide. Since screening for ESBL is not … …Current Research in Microbiology, Vol. 2, Issue 2 · 6 Mar 2012 · 7,826 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Impact of Health Technology Assessment on Decision-Making Processes in Public Versus Not-for-Profit Private HospitalsHafizah Besar Saaid, Donald Stewart, Ian England, Nilesh ParmarProblem statement: The goal of this study is to extend research on Evidence-Based Practice (EBP) implementation by examining the decision-making processes for acquiring new health technologies in selected hospitals in Southeast Queensland, Australia. Both a decision-making model and a mini-Health Technology Assessment (HTA) model guide the approach and analysis in this study. We anticipated that both public and private sector … …Current Research in Medicine, Vol. 2, Issue 2 · 4 Oct 2011 · 9,071 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIs Wright Test an Appropriate Screening Test for Diagnosis of Brucellosis?Behzad Mohsenpour, Shahla Afrasiabian, Katayoon Hajibagheri, Ebrahim GhaderiProblem statement: Diagnosis of brucellosis is generally based on culture, polymerase chain reaction and serology. The first two methods are not accessible in all parts of world and are expensive. The routine method for diagnosis of brucellosis is considering Wright test as the first screening test; if the results are Wright positive’ Wright would be the next choice otherwise 2ME … …American Journal of Infectious Diseases, Vol. 7, Issue 2 · 17 Sep 2011 · 16,762 accessesView PDF Cite

Research ArticleOpen accessIn the abstractLaser Therapy of Irradiated Traumatized Skeletal Muscles and State of Immune System in AnimalsNelly Bulyakova, Svetlana Zubkova, Valentina AzarovaProblems statement: This study was designed to examine the effect of laser therapy on regeneration of traumatized skeletal muscles and on dynamics of immune responses in thymus and bone marrow under ionizing radiation. Approach: After local X-ray radiation of both rat gastrocnemius muscles at a dose 20 Gy or after total γ-irradiation of animals at a semiletal dose 6 Gy, … …OnLine Journal of Biological Sciences, Vol. 11, Issue 2 · 27 Aug 2011 · 8,198 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMyocardial Motion Analysis of Echocardiography Images using Optical Flow Radial Direction DistributionSlamet Riyadi, Mohd Marzuki Mustafa, Aini HussainProblem statement: Myocardial motion is important information for physicians in diagnosing cardiac abnormalities. The motion vector of myocardial can be computed using optical flow technique, which then can be further analyzed based on its magnitude and angle. In practice, physicians are not concern about the angle of vector itself, but are more interested on whether a segment is moving to … …Journal of Computer Science, Vol. 7, Issue 7 · 28 Jun 2011 · 6,635 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffects of Intraarticular Tramadol Administration on Biochemical and Cytological Properties of Equine Synovial Fluid: Comparison with LidocaineAlireza Raayat Jahromi, Abutorab Tabatabaei Naeini, Saeed NazifiProblem statement: Diagnostic and therapeutic arthroscopic surgeries are procedures performed quite frequently in equine practice; and are considered to cause some degree of postoperative pain. The aim of the present study was to evaluate the equine synovial fluid biochemical and cytological changes following intra-articular administration of tramadol as a potential analgesic. Approach: Six adult healthy donkeys were selected after clinical … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 14 Jun 2011 · 7,514 accessesView PDF Cite

Research ArticleOpen accessIn the abstractInfluence of Quercetin on Diabetes-Induced Alteration in CYP3A Activity and Bioavailability of Pioglitazone in RatsSudhir Niranjan Umathe, Pankaj Vinod Dixit, Jignesh Manubhai Vaghasiya, Nishant Sudhir JainProblem statement: Quercetin-a common bioflavonoid, is present in herbal preparations consumed by diabetic patients along with routine anti-diabetic agents. We recently showed that quercetin increases the bioavailability of pioglitazone in non-diabetic rats. Thus, present study investigated whether this pharmacokinetic interaction is also evident in diabetic animals, especially because diabetic subjects have altered gastrointestinal (GI) function and CYP3A activity. Approach: The … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,818 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Role of Treg Cells in the Cancer Immunological ResponseZhi-Zhang Yang, Stephen M. AnsellProblem statement: T cell-mediated immunosuppression has been observed for decades without clarification as to which factor was responsible for this observation. The identification of CD4+CD25+ regulatory T (Treg) cells represents a milestone in the filed of immunology and provides an explanation for T-cell-mediated immunosuppression. Although Treg cells were originally identified for their ability to prevent organ-specific autoimmune disease in mice, … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,518 accessesView PDF Cite