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87 articles for “Cell Culture”
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Research ArticleOpen accessIn the abstractInternalizing Versus Non-internalizing Receptors for Targeting L-Methioninase to Cancer CellsXiao-Ping Zang, Naveen R. Palwai, J. T. Pento, Roger G. HarrisonWe reported previously that L-methioninase targeted to the urokinase receptor of MCF-7 breast cancer cells is significantly more effective in inhibiting cell proliferation and migration than free L-methioninase both in vitro and in vivo. L-methioninase was targeted by linking at its amino terminus to an amino-terminal fragment (ATF) of urokinase. The ATF was selected for targeting because is has previously … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,818 accessesView PDFCite
Research ArticleOpen accessIn the abstractClozapine and its Major Stable Metabolites, N-desmethylclozapine and Clozapine N-oxide do not Affect Human Bone Marrow Stromal Cells in vitroAvril Pereira, Brian DeanTreatment of refractory schizophrenia with the atypical antipsychotic drug clozapine is associated with life-threatening agranulocytosis, characterised by a drop in neutrophil count. Theoretically, toxicity may be accounted for by direct action of parent drug or one of its stable metabolites on bone marrow stroma given importance of these cells to neutrophil maturation. Effects of clozapine, N-desmethylclozapine and clozapine N-oxide on … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 7,111 accessesView PDFCite
Research ArticleOpen accessIn the abstractHuman Latrophilin-2 is Expressed in the Cytotrophoblast and Syncytiotrophoblast of Placenta and in Endothelial CellsGunda Herberth, Anke Stein, Jens Glienke et al.Latrophilin-2 is a member of the family of adhesion-GPCRs that is characterised by a long N-terminus which contains motifs identified in proteins involved in cell adhesion. We were interested in determining the expression pattern of human latrophilin-2 and to perform a biochemical characterisation of this protein. The expression pattern of latrophilin-2 was analysed in human organs, tissues and cell lines. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 3 · 30 Sep 2005 · 8,058 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Short Term in vitro Stress Hormone Exposure on Regulatory T Cell Number and Function in AsthmaKristina E. Rehm, Gailen D. Marshall, Jr.Asthma is characterized by alterations in the immune system, including regulatory T cells (Treg). Further alterations in Treg numbers and/or function caused by stress hormones may be a contributing factor in asthma pathogenesis. We compared Treg populations and the effects of Dexamethasone (DEX, a laboratory analog of cortisol) on Treg cell number and function in patients with asthma and a … …American Journal of Immunology, Vol. 11, Issue 1 · 24 Apr 2015 · 6,610 accessesView PDFCite
Research ArticleOpen accessIn the abstractSwiftlet Bacteriophages Concerning Diversity and Biological Features in South Kalimantan, IndonesiaSiti Gusti Ningrum, Hana Cipka Pramuda Wardhani, Intan Permatasari HermawanWe aimed to isolate and characterize bacteriophages infecting Nitrobacter spp. from swiftlet house environments and to evaluate their biological properties as potential biocontrol agents to mitigate nitrate accumulation in edible bird’s nest (EBN) production. Environmental samples were collected from multiple swiftlet houses in South Kalimantan, Indonesia. Samples were enriched with Nitrobacter cultures, and bacteriophages were detected using spot assays followed … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 1 · 17 Apr 2026 · 1,765 accessesView PDFCite
Research ArticleOpen accessIn the abstractGlobal Viewpoint on Cultured Meat: A Bibliometric Assessment from 1952-2023Emrobowansan Monday IdamokoroThis study aimed to describe the global outlook of research publications on cultured meat using bibliometric assessment approach from 1952-2023. A total of 1108 research articles were collected from Scopus data archive with average citations per doc and co-authors per document ratio of 28.74 and 4.46. The results of focus for this study of discourse include author key words, keyword … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 18 Sep 2025 · 4,093 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,949 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Gliflozin Therapy on TNF-α Secretion by Cultured Monocytes in Patients with DiabetesTatiana Vladimirovna Kirichenko, Leyla Azimovna Bochkareva et al.Currently it’s well established that chronic inflammation is a key pathogenetic mechanism in the development of Type 2 diabetes. The study aims to explore the inflammatory response of monocytes in diabetic patients compared to healthy subjects, focusing on TNF-α and to investigate the impact of SGLT2 inhibitors on monocyte inflammation. The study included 20 patients with newly diagnosed type 2 … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 4,825 accessesView PDFCite
Research ArticleOpen accessIn the abstractBrevibacillus Thermoruber 9X-GLC, Bacteria Isolated from Hot Compost, Producer of a Beta-Glucosidase Resistant to Glucose InhibitionAlejandro Sosa-Peinado, María Eugenia Hidalgo-Lara, Miguel Ángel Plascencia-Espinosa et al.The thermotolerant strain Brevibacillus thermoruber 9X-GLC produces large amounts of β-D-glucosidase and cellobiohydrolase when grown on cellobiose and avicel. 9X-GLC was isolated from hot compost of sugarcane bagasse and filter mud and selected for its high enzymatic activity from a Bacilli collection of 77 isolates from soils and compost. Culture supernatants and ultrafiltered concentrates from shaken flask cultures of 9X-GLC … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 20 Oct 2017 · 8,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression of Exosome-Derived MicroRNAs miR-21 and miR-135 are Differentially Regulated Among Dental Pulp Stem CellsMatthew Hunsaker, Brandon Richards, Adelle Fuller et al.Dental Pulp Stem Cells (DPSCs) are a type of mesenchymal stem cell that has the potential to differentiate into various types of cells and tissue. Previous research has demonstrated that DPSCs can be easily accessed and isolated from both permanent and deciduous teeth, such as wisdom teeth or third molars, although there is less information available about the mechanisms and … …Current Research in Medicine, Vol. 11, Issue 1 · 10 Jan 2023 · 10,541 accessesView PDFCite