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74 articles for “Antibiotic-Resistance”
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Research ArticleOpen accessIn the abstractINHIBITORY ACTIVITY OF POTENTOX AGAINST DNA GYRASE OF ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiDNA gyrase, a type II topoisomerase catalyzes the supercoiling of relaxed closed circular DNA. In this report we evaluated the in vitro inhibitory effect of non antibiotic adjuvant compounds disodium edetate and sodium citrate against supercoiling activity of bacterial DNA gyrase. Further, we assessed the effect of different drugs alone and in combination with one or more adjuvants in overcoming … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 8 Feb 2014 · 7,291 accessesView PDFCite
Research ArticleOpen accessIn the abstractSYNERGY OF A NOVEL ANTIBIOTIC ADJUVANT ENTITY AGAINST MULTI DRUG RESISTANT ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiIn the present investigation, we investigated the in vitro interaction of ceftriaxone plus sulbactam with disodium edetate, a Non Antibiotic Adjuvant (NAA) against selected clinical isolates and in vitro susceptibility studies were also performed. The isolates were tested against a range of ratios of ceftriaxone and sulbactam using a microdilution checkerboard method. Having determined the appropriate ratios of ceftriaxone plus … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 1 Nov 2013 · 7,419 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiogram of Bacteria Isolated from Kunun-Zaki Drink Sold in Keffi MetropolisMakwin Danladi Makut, Mary Azumi Nyam, Smart Obumneme Obiekezie, Aisha Eleojo AbubakarKunun-zaki drink is a locally prepared indigenous non-alcoholic beverage that is widely produced and consumed in Nigeria. Standard microbiological methods were employed to isolate bacteria from Kunun-zaki drink sold in Keffi metropolis, Nasarawa State, Nigeria. Samples of Kunun-zaki drink were collected from ten (10) different locations and their bacteriological loads were determined in terms of total bacterial counts using standard … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 9 Sep 2013 · 8,464 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of Heterogeneous Glycopeptide Intermediate Resistance in Methicillin-Resistant Staphylococcus aureusManu Chaudhary, Anurag PayasiMultidrug resistant Methicillin-Resistant Staphylococcus Aureus (MRSA) is a major cause of nosocomial and community acquired infections and is on the rise. The aim of this investigation was to explore the prevalence of MRSA and heterogeneous Glycopeptide Intermediate Staphylococcus Aureus (hGISA) in various clinical samples, to investigate the various antibiotic resistant determinant genes among these strains collected from north and west … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 4 Sep 2013 · 7,203 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpidemiology of Intensive Care Unit Infections and Impact of Infectious Disease Consultants in Managing Resistant InfectionsK. P. Ravi, Suresh Durairajan, Sankalp Parivar et al.Choice of empiric antibiotics in India have generally been guided by western data and guidelines. However, validity and applicability of western guidelines in the Indian setting is not known. The aim of our study was to explore microbial prevalence and resistance patterns in a tertiary care Intensive Care Unit (ICU) in India and to determine whether western guidelines are still … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 28 Apr 2013 · 7,952 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Several Antibiotics on Lactococcus garvieae Isolated from Jordanian Dairy ProductsNizar Issa AlrabadiThis study investigated the antibiotic resistance profile of the L. garvieae isolated strains from Jordanian dairy products. Disk diffusion method was used. In particular, different antibiotics were tested against L. garvieae; the antibiotic disks were Trimethoprim (5 µg), Clindamycin (2 µg), Nitrofurantoin (300 µg), Erythromycin (15 µg), Ampicillin (15 µg), Trimethoprim/Sulfamethoxazole (1.25/23.75 µg Polymyxin B (300U) and Tetracycline (30 µg). … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 4 · 28 Dec 2012 · 7,625 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Antimicrobial Stewardship Programme on Carbapenem Resistance in Gram Negative Isolates in an Indian Tertiary Care HospitalNamita Jaggi, Pushpa Sissodia, Lalit SharmaProblem statement: Increasing Antimicrobial resistance in the World is constantly becoming a Global threat and there is an urgent need to prevent its spread. Various studies of last decade have shown reduced trends of antimicrobial resistance in the pathogens as an outcome of the Antimicrobial Stewardship Programs. In view of this, the present four years’ study was carried out to … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 2 Oct 2012 · 7,627 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeveloping a System for Antibacterial Treatment of Dental Caries using Culture Based ApproachM. Mishra, S. Ghosh, L. E. Alex et al.Problem statement: Dental caries is a chronic disease worldwide, caused mainly by microbes. The orthograde approaches still remain the only option of treatment. Lack of rapid antibiotic sensitivity determination of the dental pathogen is a rate limiting step in the field of Dental Microbiology. Approach: The culture dependent analysis was used for the study of oral microflora from five healthy … …OnLine Journal of Biological Sciences, Vol. 12, Issue 2 · 18 May 2012 · 9,064 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Sensitivity Pattern of Blood Isolates of Acinetobacter Species in a Tertiary Care Hospital: A Retrospective AnalysisP. S. Shareek, D. Sureshkumar, Ramgopalakrishnan et al.Problem statement: Multi-drug resistant Acinetobacter bacterium is one of the major causes of sepsis in ICUs in tertiary care hospitals in India. In this report we describe the antibiotic sensitivity patterns of Acinetobacter species isolated from blood over a one year period at a tertiary care hospital. Approach: We retrospectively analyzed the sensitivity pattern of Acinetobacter species isolated from blood … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 24 Mar 2012 · 8,570 accessesView PDFCite
Research ArticleOpen accessIn the abstractUse of Enterobacterial Repetitive Intergenic Consensus PCR in Detecting Target(s) of Hapalindole-T, From a Cyanobacterium, in Escherichia Coli: In Silico ValidationManoj K. Tripathi, Maheep Kumar, Vinay K. Singh et al.Problem statement: Identification of newer biomolecule as well as targets are a rising concern because of increasing drug resistance in bacteria. We have isolated a broad spectrum antibiotic biomolecule Hapalindole-T from a cyanobacterium, Fisherella sp. growing on local Azadirachta indica tree bark. A model bacterium E. coli was screened spontaneously for Hap-T resistance. These resistant strains of E. coli were … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 3 Mar 2012 · 13,780 accessesView PDFCite