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Research ArticleOpen accessEvery word in the titleAntimicrobial Activity Studies of Bactoriocin Produced by Lactobacilli Isolates from Carrot KanjiHarshada M. Sowani, Prakash ThoratProblem statement: In the present study, Staphylococcus aureus a causative agent of food poisoning is selected as a test organism to study the antimicrobial effect of bacteriocin. S. aureus produces number of exotoxins and enterotoxins which enters the body via contaminated food causing illness. Approach: In this case the use of antibiotics is one of the ways of treatment, but … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 2 Mar 2012 · 8,548 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of CurcuminM. Venkata, R. Sripathy, D. Anjana et al.Problem statement: Curcumin the active component of turmeric is known for its wide biological actions. Extensive studies on curcumin highlighted its anti-inflammatory, anti-oxidant, anti-microbial, anti-carcinogenic and anti-coagulant activity. The anti-inflammatory activities of curcumin have been demonstrated both in vitro and in vivo. Though curcumin and its anti-inflammatory properties are well documented, the exact mechanism of action and effective in vivo … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 9,006 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleExtraction and Evaluation of Antibacterial Activity from Selected Flowering PlantsErlina Abdullah, Raha Ahmad Raus, Parveen JamalThe huge diversity of Malaysian flora has various chemical constituents that make them as outstanding natural product candidates for the treatment of infectious diseases. The screening practice for phytochemical compound in them is essential to explore more natural sources to replace synthetic antibiotics, which generally have side effects such as hypersensitivity, immune-suppression and allergic reactions. Antibacterial activities have been detected … …Current Research in Medicine, Vol. 3, Issue 1 · 20 Feb 2012 · 16,320 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntimicrobial Activity of Ficus benghalensis and Ficus racemosa roots L.Krishna Murti, Upendra KumarProblems statement: To evaluate the antimicrobial activity of aqueous and ethanolic extracts of Ficus benghalensis and Ficus racemosa against three bacterial strains that is Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumonia. Approach: The different concentrations viz. 25, 50 and 75 mg mL-1 of aqueous as well as ethanolic extract solutions of roots of Ficus benghalensis and Ficus racemosa were tested … …Current Research in Microbiology, Vol. 2, Issue 1 · 25 Jan 2012 · 14,492 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDesign, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular AgentsMehul M. Patel, Mahesh T. ChhabriyaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Although many active antitubercular agents have since been developed, drug resistance will continue to be a problem. Therefore, there is a clear … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,432 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntibacterial Activity of β-Cyclodextrin and 2-Hydroxypropyl-β-Cyclodextrin Trimethoprim ComplexesHsien-Kuo Sun, Madhumathi Seshadri, Scott Lingard et al.Problem statement: Cyclodextrin complexation has previously been shown to improve the solubility and dissolution properties of trimethoprim; however, no report provides an account of the effect cyclodextrin complexation has on the antibacterial activity of this agent. Approach: β-cyclodextrin and 2-hydroxypropyl β-cyclodextrin inclusion complexes of trimethoprim were prepared and confirmed by differential scanning calorimetry and proton nuclear magnetic resonance. The in-vitro … …Current Research in Microbiology, Vol. 2, Issue 1 · 26 Oct 2011 · 14,806 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnticancer Activity of Some New Synthesized Tetrahydroquinoline and Tetrahydrochromene Carbonitrile DerivativesUsama W. Hawas, Mohamed A. Al-Omar, Abd El-Galil E. Amr, Abu El-Ftouh G. HammamProblem statement: In continuation to our search for new heterocyclic chemistry based anticancer, the suggestion, synthesis, structure elucidation of some naphthalene, chromene and quinoline derivatives 3-7 were realized herein using 3-methylcyclohexanone 1 as a starting material. Approach: The antitumor activities of the newly synthesized compounds 4-7 were evaluated utilizing 60 different human tumor cell lines, representing leukemia, melanoma, lung, colon, … …American Journal of Applied Sciences, Vol. 8, Issue 10 · 14 Sep 2011 · 7,487 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAttitudes of High School Students toward Physical Education and Their Sport Activity PreferencesHoward Z. Zeng, Michael Hipscher, Raymond W. LeungProblem statement: Identifying and understanding correlates of school children’s physical education activity participation are critical to promoting current and lifelong physical activity participation of children. Among other factors, children’s attitudes are considered to be a key element influencing physical activity participation. Children who have more positive attitudes toward physical activity are reported to be more likely to participate in physical … …Journal of Social Sciences, Vol. 7, Issue 4 · 15 Aug 2011 · 19,921 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTheoretically Predicted Descriptors Based Quantitative Structure Activity Relationship Study of the Activity of Acridines Against B-16 MelanomaBahjat A. Saeed, Rita S. Elias, Sadiq M-H. Ismael, Kawkab A. HussainProblem statement: The probability of success and reducing time and coast in drug discovery process could be increased on the basis of QSAR techniques. The study involves the QSAR investigation of 20 bioactive acridines that have activity against Approach: Molecular descriptors, total energy, van der Waals volume, molecular volume, HOMO energy, HOMO-LUMO energy gap, polarizability, refractivity, bond angle of C8-N9-C2 … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 18 Jul 2011 · 7,695 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSocio-Economic Statues and Physical Activity Levels of 3th Grade Students: A Case Study in Istanbul Beykoz ProvincePinar Salih, Kucuk Yetgin Meral, Kaya Fatih et al.Problem statement: The children and adolescent period is critical time to acquire positive lifestyle habits. The aim of this study is to investigate the physical activity level of children aged between 9-10 accordance with their BMI’s and socio-economic level of their school environments. This study also reviewed the articles about physical activity level of children, its relation to their socio-economic … …Journal of Social Sciences, Vol. 7, Issue 3 · 16 Jul 2011 · 8,675 accessesView PDFCite