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Research ArticleOpen accessIn the abstractComparison and Parametric Study of Flameless Oxidation in a Gas Turbine Using Two Kinetics MechanismsMohamed Hamdi, Hmaïed Benticha, Mohamed SassiThe so-called "Flameless Oxidation" is a novel combustion mode, in which combustion products are re-circulated and mixed into the fresh incoming fuel and air streams. This reduces the concentration of the reactants and thereby reducing the reaction rate through avoiding the formation of sharp high temperature zones in the combustion chamber. Flameless combustion has been acknowledged as one of the … …American Journal of Environmental Sciences, Vol. 4, Issue 5 · 31 Oct 2008 · 6,957 accessesView PDFCite
Research ArticleOpen accessIn the abstractTamoxifen Drug Loading Solid Lipid Nanoparticles Prepared by Hot High Pressure Homogenization TechniquesNagi A. ALHaj, Rasedee Abdullah, Siddig Ibrahim, Ahmad BustamamAs drug delivery systems Nanoparticulate widely investigated because of many advantages such as smaller size, controlled drug release potential, targeting ability, enhancement of therapeutic efficacy and reduction of toxicity. So, Solid Lipid Nanoparticles have recently received considerable attention as alternative drug delivery carrier. In this study Solid Lipid Nanoparticles (SLNs) containing tamoxifen, nonsteroidal antiestrogens have been loaded and to be … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 3 · 30 Sep 2008 · 15,176 accessesView PDFCite
Research ArticleOpen accessIn the abstractBridging from Cells to Cognition in Autism Pathophysiology: Biological Pathways to Defective Brain Function and PlasticityMatthew P. Anderson, Brian S. Hooker, Martha R. HerbertWe review evidence to support a model where the disease process underlying autism may begin when an in utero or early postnatal environmental, infectious, seizure, or autoimmune insult triggers an immune response that increases reactive oxygen species (ROS) production in the brain that leads to DNA damage (nuclear and mitochondrial) and metabolic enzyme blockade and that these inflammatory and oxidative … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 17,461 accessesView PDFCite
Research ArticleOpen accessIn the abstractResistance Factors in the Implementation of Software Process Improvement Project in MalaysiaMohd Hairul Nizam Md. Nasir, Rodina Ahmad, Noor Hafizah HassanFor the past two decades, improving the quality of software has become an important agenda in the software industries as they have been assessed according to standards such as the CMM, CMM-I, ISO 9000 SIX-SIGMA and etc. As the result, software process improvement project implementations have been the main targets by most software companies. However, many initiatives are facing variety … …Journal of Computer Science, Vol. 4, Issue 3 · 31 Mar 2008 · 7,334 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn the Hormetic Behaviour of Drugs Binding to Different Redox States of Amine Oxidase EnzymesDeepak Narang, G. Reid McDonald, David J. Smith et al.Classical monoamine oxidases and copper-containing semicarbazide-sensitive amine oxidases are drug targets for a variety of established and novel pharmaceuticals used to treat conditions such as depression, Parkinsonism and inflammatory disorders. Development of enzyme inhibitors, both historically and currently, assumes an underlying adherence of these enzymes to Michaelis-Menten kinetic principles. In this mini-review, we discuss historical data from several laboratories and … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 6,931 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormesis and Exercise: How the Cell Copes with Oxidative StressLi Li Ji, Zsolt Radak, Sataro GotoContraction-induced production of reactive oxygen and nitrogen species has been shown to cause oxidative stress to skeletal muscle, heart and other organs. As an adaptive response, muscle antioxidant defense systems are upregulated in response to exercise to restore intracellular prooxidantantioxidant homeostasis. Thus, both young and old animals and humans involved in regular exercise have shown reduced oxidative damage during acute … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,818 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunopathogenesis of Dengue Hemorrhagic FeverHuan-Yao Lei, Kao-Jean Huang, Yee-Shin Lin et al.Dengue virus infection causes Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) whose pathogeneses were not clearly understood. A new hypothesis of immunopathogenesis is proposed for the development of the DHF/DSS. An aberrant immune over-activation after dengue virus infection not only impair the immune response to clear the virus, but also result in overproduction of cytokines … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 14,773 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimal Production Planning of Electricity from Coal-Fired Power Plant Networks under Environmental ConsiderationsHabib H. Al-Ali, Yousef Saif, Ali Elkamel, Ali LohiIn this study, electricity production from a network of coal power plants and under environmental constraints is considered. Several pollutants are incorporated into the decision planning process including nitrogen oxides (NOx), sulfur oxides (SOx) and mercury (Hg). A Nonconvex Mixed Integer Nonlinear Programming (MINLP) model was first developed to assist in the evaluation process. An exact linearization of the nonconvex … …American Journal of Engineering and Applied Sciences, Vol. 1, Issue 4 · 31 Mar 2008 · 7,074 accessesView PDFCite
Research ArticleOpen accessIn the abstractHIV Medication Adherence and Substance Use: The Smartest Women’s ProjectEliot Lopez, Deborah L. Jones, Mary Ishii et al.Antiretroviral (ARV) medication for substance users has been a controversial issue with respect to whether current substance users can successfully maintain their medication regimens. This study compared ARV adherence across current substance users, former substance users and those with no history or current use and the relative impact of a medication adherence intervention on all three groups. Of the 481 … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,201 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunodeficient Parameters in the HIV-1 Transgenic Rat ModelSulie L. Chang, Frank Ocasio, Jose A. BeltranRecently an HIV-1 transgenic (HIV-1Tg) rat model was created that carries a gag-pol-deleted HIV-1 genome under the control of the HIV-1 viral promoter. However, other viral proteins are expressed in most organs and tissues, and are found in the circulating blood. Since HIV-1 targets the immune system in humans, we examined two immunological parameters, leukocyte-endothelial adhesion (LEA) and inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,839 accessesView PDFCite