Research ArticleOpen accessIn the abstractMaking Sense of Industrial Accidents: The Role of Job SatisfactionSeth A. Gyekye, Simo SalminenThe study examined causality attributions made for workplace accidents and how these attributions may be influenced by job satisfaction. It was part of an extensive exploratory work on causal attributions for industrial accidents in Ghana's work environment. It was carried out in a field setting where the participants were actual accident victims (n=121), co-workers (n=117) and supervisors (n=82) at their … …Journal of Social Sciences, Vol. 2, Issue 4 · 31 Dec 2006 · 7,252 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Phenotypically Suppressed Cancer Cell As a Therapeutic TargetKimberly D. Kyker, Jessica E. Thorpe, Satyendra S. Shenoy et al.Bladder cancer recurs in up to 70% of patients judged to be tumor-free after treatment. Like other cancers, delayed appearance of metastases is common. These findings suggest the malignant phenotype can be suppressed, to emerge later. Following up on previous research in our laboratory showing that normal extracellular matrix can suppress the malignant phenotype of bladder cancers, we here demonstrate … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,471 accessesView PDFCite
Research ArticleOpen accessIn the abstractConsequence on Treatment of TB Patients Affected by HIV/AIDS A Conceptual ResearchSarder N. Uddin, S. J. Hossain, Md. N. Huda et al.Mycobacterium tuberculosis is an ancient malady, which is one of the world’s most wide spread infectious bacterial agents. Fully one-third of the world’s population is already infected with Mycobacterium tuberculosis, with the greatest burden of disease and infection borne by people in developing countries. Tuberculosis disease is still out of control. Alarming spread of Human Immunodeficiency Virus (HIV) and emergence … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 7,017 accessesView PDFCite
Research ArticleOpen accessIn the abstractInternalizing Versus Non-internalizing Receptors for Targeting L-Methioninase to Cancer CellsXiao-Ping Zang, Naveen R. Palwai, J. T. Pento, Roger G. HarrisonWe reported previously that L-methioninase targeted to the urokinase receptor of MCF-7 breast cancer cells is significantly more effective in inhibiting cell proliferation and migration than free L-methioninase both in vitro and in vivo. L-methioninase was targeted by linking at its amino terminus to an amino-terminal fragment (ATF) of urokinase. The ATF was selected for targeting because is has previously … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,817 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of AP-1 Antagonism in Growth Inhibition of Cervical Cancer Cell Lines by RetinoidsShennan Lu, Doris M. BenbrookRetinoid compounds induce multiple molecular effects that need to be taken into consideration in the development of theses agents as pharmaceuticals for cancer chemoprevention. Inhibition of cancer cell growth by retinoids is thought to occur through at least two mechanisms of transcriptional regulation resulting from direct binding of retinoids to nuclear retinoid receptors (RARs and RXR’s). First, the nuclear receptors … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,477 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Mechanisms for Altered Glucose Homeostasis in HIV InfectionPaula W. HruzA complete understanding of the molecular mechanisms leading to HIV-associated insulin resistance remains elusive. Complex interrelationships between genetic predisposition, disease-related body changes and multidrug therapy all contribute to alterations in glucose homeostasis. These abnormalities can be differentiated between acute and reversible changes directly induced by HAART medications and more chronic and less reversible changes due to the development of lipodystrophy … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,877 accessesView PDFCite
Research ArticleOpen accessIn the abstractAbnormal Glucose Regulation and Treatment Strategies for Insulin Resistance HIV-Infected PatientsSteven GrinspoonHIV-infected patients receiving highly active antiretroviral therapy often demonstrate abnormalities in glucose regulation, in association with changes in fat distribution[1,2]. In the majority of cases, these abnormalities are best characterized by insulin resistance and impaired glucose tolerance, rather than overt diabetes mellitus and fasting hyperglycemia. Insulin resistance may result from direct effects of antiretroviral therapy, changes in fat distribution or … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,387 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Mutagenesis of Streptokinase Producing BacteriaThaer Taleb Abed Abdelghani, Adinarayana Kunamneni, Poluri EllaiahOf 103 β-haemolytic Streptococci (with haemolytic activity) in total were isolated from different samples of blood and biomass from infected throat, 47 isolates exhibited streptokinase (SK) activity. T3, identified as a new variant of Streptococcus equisimilis, was found to be excellent SK producer in submerged fermentation and was selected for strain improvement studies. This strain was mutagenized by UV and … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractRational Rules of Thumb in Finite Dynamic Games N-person Backward Induction with Inconsistently Aligned Beliefs and Full RationalityYanis VaroufakisRecent work has cast considerable doubt on the plausibility of specific assumptions about how rational agents form out-of-equilibrium beliefs in finite extensive games in which beliefs are induced backwards. The point is that the resulting consistently aligned beliefs are incoherent in view of the counterfactuals they rely on. This study asks: How will the possibility of inconsistently aligned beliefs affect … …American Journal of Applied Sciences, Vol. 2, Issue 13 · 16 Dec 2005 · 8,114 accessesView PDFCite
Research ArticleOpen accessIn the abstractERCP Related SepsisIffet Palabıyıkoglu, Emin Tekelı, Derya Aysev et al.Endoscopic procedures performed worldwide have increased considerably in recent years. In addition to diagnosis, many cases previously necessitating surgery now often can be carried out by endoscopic techniques. However, endoscopy has introduced its own infection risk. Most reports of gastrointestinal endoscopy-associated infection describe sepsis after endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary tract obstruction. During this study, which was … …American Journal of Infectious Diseases, Vol. 1, Issue 2 · 30 Jun 2005 · 7,016 accessesView PDFCite