Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

589 results for “Agent”
Set a search alert
Research ArticleOpen accessIn the abstractHIV-1-Specific CTL Recognizing a Scarce Epitope Are Not Suppressed by HIV-1 Protease InhibitorsOtto O. YangHIV-1-protease inhibitors have received growing attention as agents that can affect proteases in human proteasomes, with potentially deleterious effects for HIV-1-specific cellular immunity. Studying the antiviral activity of HIV-1-specific CTL that recognize an epitope that is presented at limiting concentrations on infected cells, we find that several HIV-1 protease inhibitors do not affect their function. These data indicate that these … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,016 accessesView PDFCite
Research ArticleOpen accessIn the abstractTwo Main Methods for Utility Sharing in Joint Business: A DiscussionRafel Amer, Francesc Carreras, Antonio MagañaOne of the main purposes of any theory of joint business is to provide a convincing way for sharing the total utility available to the set of agents. The proportional rule is widely applied in practice but people using this method should be warned that it is not as innocent, effective, fair and consistent as it seems at first glance. … …Journal of Mathematics and Statistics, Vol. 3, Issue 1 · 31 Mar 2007 · 6,894 accessesView PDFCite
Research ArticleOpen accessIn the abstractCurrent Approaches for the Prevention of Surgical Site InfectionsSander Florman, Ronald Lee NicholsSurgical site infections (SSIs) are the most common type of nosocomial infection among surgical patients and are commonly caused by the patients’ own microbial flora. The prevalence of SSI is a major concern because of the associated increase in the incidence of morbidity and mortality, length of hospitalization and cost of care for postoperative patients. Key factors that determine whether … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 7,824 accessesView PDFCite
Research ArticleOpen accessIn the abstractSuccessful Treatment of Both Mother and Infant in Pregnancy-Associated Group A Streptococcal Toxic Shock SyndromeTakayuki Tanaka, Kousaku Matsubara, Yumiko Umemoto et al.All perinatal cases of group A streptococcal toxic shock syndrome (STSS) previously documented in English literature have been fatal for the mother, the fetus or both. We present the first report of successful treatment of a mother-infant pair with perinatal STSS. A pregnant woman developed STSS at 34 weeks’ gestation 3 h after delivery, following a 25-h history of fever … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 7,089 accessesView PDFCite
Research ArticleOpen accessIn the abstractUnconventional Approach for Demineralization of Deproteinized Crustacean Shells for Chitin ProductionN.S. Mahmoud, A.E. Ghaly, F. ArabChitin is a versatile environmentally friendly modern material. It has a wide range of applications in areas such as water treatment, pulp and paper, biomedical devices and therapies, cosmetics, membrane technology and biotechnology and food applications. Crustacean waste is the most important chitin source for commercial use. Demineralization is an important step in the chitin purification process from crustacean waste. … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 1 · 31 Mar 2007 · 8,799 accessesView PDFCite
Research ArticleOpen accessIn the abstractMaking Sense of Industrial Accidents: The Role of Job SatisfactionSeth A. Gyekye, Simo SalminenThe study examined causality attributions made for workplace accidents and how these attributions may be influenced by job satisfaction. It was part of an extensive exploratory work on causal attributions for industrial accidents in Ghana's work environment. It was carried out in a field setting where the participants were actual accident victims (n=121), co-workers (n=117) and supervisors (n=82) at their … …Journal of Social Sciences, Vol. 2, Issue 4 · 31 Dec 2006 · 7,252 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Phenotypically Suppressed Cancer Cell As a Therapeutic TargetKimberly D. Kyker, Jessica E. Thorpe, Satyendra S. Shenoy et al.Bladder cancer recurs in up to 70% of patients judged to be tumor-free after treatment. Like other cancers, delayed appearance of metastases is common. These findings suggest the malignant phenotype can be suppressed, to emerge later. Following up on previous research in our laboratory showing that normal extracellular matrix can suppress the malignant phenotype of bladder cancers, we here demonstrate … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,471 accessesView PDFCite
Research ArticleOpen accessIn the abstractConsequence on Treatment of TB Patients Affected by HIV/AIDS A Conceptual ResearchSarder N. Uddin, S. J. Hossain, Md. N. Huda et al.Mycobacterium tuberculosis is an ancient malady, which is one of the world’s most wide spread infectious bacterial agents. Fully one-third of the world’s population is already infected with Mycobacterium tuberculosis, with the greatest burden of disease and infection borne by people in developing countries. Tuberculosis disease is still out of control. Alarming spread of Human Immunodeficiency Virus (HIV) and emergence … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 7,017 accessesView PDFCite
Research ArticleOpen accessIn the abstractInternalizing Versus Non-internalizing Receptors for Targeting L-Methioninase to Cancer CellsXiao-Ping Zang, Naveen R. Palwai, J. T. Pento, Roger G. HarrisonWe reported previously that L-methioninase targeted to the urokinase receptor of MCF-7 breast cancer cells is significantly more effective in inhibiting cell proliferation and migration than free L-methioninase both in vitro and in vivo. L-methioninase was targeted by linking at its amino terminus to an amino-terminal fragment (ATF) of urokinase. The ATF was selected for targeting because is has previously … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,817 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of AP-1 Antagonism in Growth Inhibition of Cervical Cancer Cell Lines by RetinoidsShennan Lu, Doris M. BenbrookRetinoid compounds induce multiple molecular effects that need to be taken into consideration in the development of theses agents as pharmaceuticals for cancer chemoprevention. Inhibition of cancer cell growth by retinoids is thought to occur through at least two mechanisms of transcriptional regulation resulting from direct binding of retinoids to nuclear retinoid receptors (RARs and RXR’s). First, the nuclear receptors … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,477 accessesView PDFCite