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Research ArticleOpen accessIn the abstractINHIBITORY ACTIVITY OF POTENTOX AGAINST DNA GYRASE OF ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiDNA gyrase, a type II topoisomerase catalyzes the supercoiling of relaxed closed circular DNA. In this report we evaluated the in vitro inhibitory effect of non antibiotic adjuvant compounds disodium edetate and sodium citrate against supercoiling activity of bacterial DNA gyrase. Further, we assessed the effect of different drugs alone and in combination with one or more adjuvants in overcoming … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 8 Feb 2014 · 7,288 accessesView PDFCite
Research ArticleOpen accessIn the abstractPHENOTYPING, VIRULENCE CHARACTERISTICS OF AEROMONAS SPECIES AND THE EFFECTS OF ESSENTIAL PLANT OILS AS ANTIMICROBIAL AGENTS AGAINST PATHOGENIC ISOLATES FROM DIFFERENT SOURCESAhmed M.A. Mansour, Hoda M. Zaki, Nibal A. Hassan, Nihad A.M. El-NasharAeromonas species are increasingly recognized as enteric pathogens. Faecal samples from 20 cow, 45 sheep; 60 goat and 60 camels were examined for the presence of Aeromonas species, which was also sought in the available drinking water (55 well water and 52 drinking chlorinated tap water were also examined). Aeromonas species was isolated more frequently from goats (21.7%) than from … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 18 Jan 2014 · 8,020 accessesView PDFCite
Research ArticleOpen accessIn the abstractPROCALCITONIN AS A MARKER FOR EARLY DIAGNOSIS OF SEPSISRahim Raoofi, Zahra Salmani, Fatemh Moradi et al.Sepsis is a critical condition often caused by bacterial infection and associated with death and mortality. The prognosis of this disease depends on early diagnosis and proper treatment. Definite diagnosis of sepsis is positive blood culture and this test needs a long time to perform, so other biochemical parameters such as procalcitonin serum level has been introduced. To determine sensitivity, … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 23 Dec 2013 · 7,476 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdaptogenic Potentials of Cyphostemma glaucophilla Aqueous Leaf ExtractOjogbane Eleojo, Nwodo Okwesili Fred Chiletugo, Omale JamesCytophostemma glaucophilla aqueous extract is used in Kogi and Kwara States of Nigeria to treat Kwashiorkor and to boost immunity. As part of the effort to evaluate its effect on stress, it was screened for adaptogenic potentials. This investigation was conducted using albino rats to determine the ability of this plant to increase non specific resistance against physical, biological and … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 7,118 accessesView PDFCite
Research ArticleOpen accessIn the abstractStatus of Soil Microbial Population, Enzymatic Activity and Biomass of Selected Natural, Secondary and Rehabilitated ForestsK. S. Daljit Singh, A. Arifin, O. Radziah et al.Substantial clearance of forests and conversion of forest into various land use types contribute to deterioration of soil fertility and associated nutrients loss. Soils from natural and rehabilitated forest in Chikus Forest Reserve and also enrichment planting forest and secondary forest of Tapah Hill Forest Reserve, Perak, Malaysia were selected in order to assess the influence of land use change … …American Journal of Environmental Sciences, Vol. 9, Issue 4 · 28 Aug 2013 · 7,803 accessesView PDFCite
Research ArticleOpen accessIn the abstractBio-Guided Study on Melastoma malabathricum Linn Leaves and Elucidation of its Biological ActivitiesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to isolate and identify constituents with antibacterial activity from the Methanol extract of Melastoma malabathricum leaves (MMML) through bioassay guided fractionation. Furthermore, the study scoped to evaluate the cytotoxic effects of M. malabathricum leaves fractions for possible protective effect of antoxidative constituents present in the fractions. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 9,513 accessesView PDFCite
Research ArticleOpen accessIn the abstractStaphylococcus aureus Nasal Carriage Among Injecting and Non-Injecting Drug Users and Antimicrobial SusceptibilityMojtaba Varshochi, Zahra Attari, Alka Hasani, Ali SeidiStaphylococcus Aureus (SA) is one of the most prevalent bacterial pathogens in human beings. Approximately 20% of healthy persons are persistent carriers and 60% are intermittent carriers of SA. Nasal cavity is one of the most important sites of its colonization. Intravenous (IV) drug abuse has been proposed as a risk factor for colonization of SA in the nasal mucosa. … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 23 May 2013 · 7,312 accessesView PDFCite
Research ArticleOpen accessIn the abstractRETRACTED: Evaluation of the Cytotoxic Activity of Aqueous Extract of Schinus terebinthifolius RaddiA. Arnóbio, O. N. Terra Jr., P. R.G. Lemos et al.Phytotherapy consists in all pharmaceutical preparation using certain part of plants as a feedstock with known pharmacological effects for medicinal purposes. In order to a better understanding of the biological effects associated with herbal medicines, many scientific studies have been conducted and developed in recent years. SchinusterebinthifoliusRaddi (Aroeira) is native from Peru and is also found in Europe, Asia and … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 8 Feb 2013 · 7,611 accessesView PDFCite
Research ArticleOpen accessIn the abstractTargeting Cellular Receptors as a Strategy for the Development of New Generation Mucosal VaccinesConstantine Bitsaktsis, Kari Wiedinger, Edmund Joseph GosselinMucosal pathogens are a primary source of infection that require the development of vaccines to induce a specific, protective and long lasting immune response. Despite an urgent need, development of effective mucosal immunization strategies has proven difficult. The literature was reviewed to elucidate cell specific targets that may be utilized to increase the immunogenicity of protective antigens through mucosal vaccination. … …American Journal of Immunology, Vol. 9, Issue 1 · 2 Feb 2013 · 7,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Self-Medication Among Pharmacy StudentsRiham Waisi, Laila Mouslli, Osama Hussein Mohamed Ibrahim, Suleiman Ibrahim SharifTo determine the incidence of self-medication among Sharjah university students and the impact of medical knowledge on such practice. A pre-validated questionnaire was distributed to 200 pharmacy students during May, 2012. Data were analyzed using SPSS and results expressed as counts and percentages. The overall response rate was 85% with 98% of respondents being Arabs. Females comprised about 91% of … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 4 · 15 Dec 2012 · 10,376 accessesView PDFCite