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76 articles for “toxic effects”
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Research ArticleOpen accessIn the abstractEffects of D- and L-Glucose and Mannitol on Retinal Capillary Cells: Inhibition by Nanomolar AminoguanidineYongxin Yu, Wei Li, Barbara Wojciechowski et al.Hyperglycemia may contribute directly to pericyte loss and capillary leakage in early diabetic retinopathy. To elucidate relative contributions of glycation, glycoxidation, sugar autoxidation, osmotic stress and metabolic effects in glucose-mediated capillary damage, we tested the effects of D-glucose, L-glucose, mannitol and the potentially protective effects of aminoguanidine on cultured bovine retinal capillary pericytes and endothelial cells. Media (containing 5 mM … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 7,751 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Canadian Regulations and Remediation Methods for Diesel Oil Contaminated SoilsD. G. Rushton, A E. Ghaly, K. MartinellDiesel fuel released into the environment can contaminate ground water, degrade potable water supplies and cause the collapse of fisheries. They are toxic to both animals and humans and can affect the liver, lungs, kidneys, and nervous system leading to cancer as well as immunological and reproductive effects. The objectives of this study were to review current Canadian regulations pertaining … …American Journal of Applied Sciences, Vol. 4, Issue 7 · 31 Jul 2007 · 8,764 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractHippocampal Pyramidal Cell Degeneration and Changes in Creb Protein in Datura stramonium Treated RatsPeter Etim Ekanem, Dare S. Sunday, Sunday Abba, Amanuel TesfayDatura Stramonium (DS) is a tropical shrub which is available worldwide. It has various uses and is often used to increase the intoxication of certain beverages. The seeds of this plant are very toxic but are commonly smoked in like manner as tobacco. The present study investigated the potential harmful effects of DS on pyramidal cells and CREB protein in … …Neuroscience International, Vol. 6, Issue 2 · 17 Sep 2015 · 7,066 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactivity of the Alkaloids, Norharman and L-N-Methylcrotonosine/LinearisineMargelette Ellis-Tabanor, Dwight Robinson, Eric HyslopThe toxic effects of the alkaloids, Norharman and a mixture of L-N-Methylcrotonosine/Linearisine (M/L mixture), on two organisms, Gambusia puncticulata and Veronicella sloanei were determined. The effect of the alkaloids on the fecundity of Thiara granifera was also investigated. Norharman was harmless to G. puncticulata but the M/L mixture inflicted 55.5% mortality on fish populations. The alkaloids had narcotizing, repellent and … …OnLine Journal of Biological Sciences, Vol. 15, Issue 1 · 11 Apr 2015 · 7,205 accessesView PDFCite
Research ArticleOpen accessIn the abstractSome Pollutants (PAHs and OPPs) in Caspian Sea Coast-IranChangiz MohammadizadehPAHs form one of the most important classes of persistent pollutants. Sediment samples were taken from the eastern Caspian Sea coast of Mazandaran state analyzed by (GC-MS) for PAHs. Sediment samples were collected from eastern part of southern Caspian Sea in Mazandaran Province. Stations were Amirabad (10), Sari (5), Babolsar (5) and Noushahr (5) to determinate distribution and to source … …Current Research in Geoscience, Vol. 3, Issue 2 · 10 Jun 2014 · 6,989 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Some Heavy Metals in Some Morpho-Physiological Parameters in Maize SeedlingsSali Aliu, Bekim Gashi, Imer Rusinovci et al.Nowadays the heavy-metal pollution of the soil is causing ever greater problems, exacerbated by the fact that the heavy metals accumulated in plants may, either directly or indirectly, find their way into animals and human beings. Maize is one of the world’s most important crops, ranking third after wheat and rice, so the changes induced by one of the most … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 8,432 accessesView PDFCite
Research ArticleOpen accessIn the abstractPossible Mechanism of Plumbago zeylanica in Prevention of Hepatic Dammage in Wistar RatRohit Goyal, Pyare Lal SharmaPlumbago zeylanica root has been used traditionally to treat various body ailments including liver diseases. The present study was designed to investigate the hepatoprotective effects of standardized methanolic extract of Plumbago zeylanica root on paracetamol, CCl4 and alcohol induced hepatic injuries in rats and its possible mechanism(s) of hepatoprotection. Administration of hepatotoxicants like paracetamol (3 g kg-1, p.o.) or CCl4 … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 20 Nov 2012 · 7,641 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Catha edulis on Insulin, Resistin and Cortisol Levels in Type-2 Diabetics and Non-DiabeticsMohamed Ibrahem Kotb El-Sayed, Hatem Al-Kordy AminIn this study, the biochemical effects of Catha edulis leaves chewing (as psycho stimulant and aphrodisiac) on the serum concentration of resistin, insulin, cortisol, zinc, calcium, copper and blood glucose in both healthy individuals and type 2 diabetic patients were examined. 80 male subjects aged 35-55 years were recruited in this study, 40 of them were previously diagnosed as type … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 3 · 20 Sep 2012 · 8,617 accessesView PDFCite
Research ArticleOpen accessIn the abstractEcological Monitoring of Danube water Quality in Budapest RegionHosam E.A.F. Bayoumi Hamuda, Istvan PatkoProblem statement: Serious health problems and other economic costs related to water treatment, remediation and locating a new water supply, become an evidence of water pollution caused by human activities. The main problems of the Danube River basin are associated with nutrients, organic pollution and hazardous pollutants. The aim of the study is to assess the surface water of the … …American Journal of Environmental Sciences, Vol. 8, Issue 3 · 5 Apr 2012 · 9,033 accessesView PDFCite