44 results for “mutations”

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Research ArticleOpen accessIn the abstractComparative Analysis of UGT1A9 Genetic Polymorphisms between Chinese Han and Tibetan PopulationsWei Yan, Jian Cui, Yuewen Wang et al.Although various polymorphisms have been identified in the UGT1A9 gene in the main sorts of ethnic groups in the world, no investigations have been focused on the Chinese Tibetan populations and the comparison between Chinese Tibetan and Han populations to date. This study was designed to systematically compare genetic differences between the two populations. We investigated the functional regions of … …Current Research in Medicine, Vol. 3, Issue 2 · 23 Aug 2012 · 7,641 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Widely Used Diagnostics "DNA Microarray"-A ReviewR. Manoj KumarProblem statement: DNA microarray technique is one of the latest advances in the field of molecular biology and medicine. It is a multiplex technique used in combination of bioinformatics and statistical data analysis. Since, 1995, the technique offers the possibility of conducting tens or hundreds of thousands of simultaneous hybridizations. Approach: This increased experimental efficiency permits high throughput and whole … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,787 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Use of Artificial Neural Networks in Analysis Cationic Trypsinogen Gene and Hepatitis B Surface AntigenLiu Qicai, Zeng Kai, Zhuang Zehao et al.Problem statement: More and more severe hepatitis cases reported in China are infected with HBV and the immune response of HBV will be reduced if mutations occur in the TCR, therefore it is very important to investigate the relation of T-cellular function and clinical effect by studying the function of T-cell receptor. Approach: Artificial Neural Networks (ANN) was applied to … …American Journal of Immunology, Vol. 5, Issue 2 · 30 Apr 2009 · 7,564 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAssociation between Paternal Age at Birth Time and the Risk of Offspring Developing SchizophreniaVictoria Omranifard, Ghorbanali AsadollahiSchizophrenia is the Leading psychotic disorder. It is a severe disease that involves social and interpersonal relationship of affected person and cause severe loss of function; that why many researchers wanted to know its etiologic factors. In this research, we wanted to reveal the relationship of paternal age to schizophrenia. This cross-sectional study was done on 240 patients of schizophrenia … …American Journal of Applied Sciences, Vol. 6, Issue 1 · 31 Jan 2009 · 7,287 accessesView PDF Cite