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52 results for “malignant”
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Research ArticleOpen accessIn the abstractSPECTRAL DOMAIN FEATURES FOR OVARIAN CANCER DATA ANALYSISAhmed Farag Seddik, Riham Amin Hassan, Mahmoud A. FakhreldeinThe early detection of cancer is crucial for successful treatment. Medical researchers have investigated a number of early-diagnosis techniques. Recently, they have discovered that some cancers affect the concentration of certain molecules in the blood, which allows early diagnosis by analyzing the blood mass spectrum. Researchers have developed several techniques for the analysis of the mass-spectrum curve analysis and used … …Journal of Computer Science, Vol. 9, Issue 8 · 9 Jul 2013 · 6,915 accessesView PDFCite
Research ArticleOpen accessIn the abstractMass Classification in Digital Mammograms based on Discrete Shearlet TransformJ. Amjath Ali, J. JanetThe most significant health problem in the world is breast cancer and early detection is the key to predict it. Mammography is the most reliable method to diagnose breast cancer at the earliest. The classification of the two most findings in the digital mammograms, micro calcifications and mass are valuable for early detection. Since, the appearance of the masses are … …Journal of Computer Science, Vol. 9, Issue 6 · 1 Jun 2013 · 6,549 accessesView PDFCite
Research ArticleOpen accessIn the abstractBIOENERGETICS, THE FOUNDATION OF THE FUTURE OF CANCER THERAPEUTICS A QUANTUM LEAP IN MAKINGKambiz AfrasiabiDeep understanding of the governing laws of bioenergetics of the living organism and dissection of their aberrancies, could enable us to design new treatment strategies for a vast array of disorders including malignancy and could potentially lead to major breakthroughs and cure of these devastating disorders. The modern treatment strategies currently aim at identification of a pathway considered to be … …OnLine Journal of Biological Sciences, Vol. 12, Issue 3 · 15 Aug 2012 · 7,528 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship Between Blood Fibrinogen Concentration and Pathological Features of Cancer Patients: A 139-case Clinical StudyDa-Yong Lu, Xue-Liang Chen, Min Huang et al.Angiogenesis and coagulation are among the most consistent host responses to the presence of a malignant tissue. Pathological angiogenesis and coagulation are often occurred in patients with solid tumors, especially in the occurrence of neoplasm metastasis and as targets for anti-metastatic drugs such as antiangiogenesis agents, coagulation-mediated agents and anticancer drugs. Since fibrinogen (Fib) is the most abundant and key … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 4 Sep 2010 · 7,859 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,095 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Optimized Medium for Screening of L-Asparaginase production by Escherichia coliYounes Ghasemi, Alireza Ebrahiminezhad, Sara Rasoul-Amini et al.Purified L-asparaginase II from Escherichia coli has been supplied and employed in the acute leukemia and other malignant neoplasms chemotherapy. L-asparaginase II gene (ansB) in E. coli is under regulation and certain conditions is needed for expression of this gene. In this investigation ,the various concentrations of modified M9 medium ingredients and various carbon source were tested to optimize the … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 9,698 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Interplay between p53 and p21 Tumor Suppressor Proteins in the Transformation of Colorectal Adenoma to CarcinomaA.S. Abdulamir, R.R. Hafidh, L.K. Mahdi et al.This study was carried out for evaluating the interplay of p53, p21 and Ki-67 proteins along the colorectal adenoma-carcinoma oncogenic transformation sequel. Therefore, Fifty colorectal cancer and 14 adenoma patients were involved. The histopathological expression of p53, p21 and Ki-67 proteins was evaluated by immunohistochemistry assay. The results revealed that remarkable overexpression of p53 protein was seen in the tumorous … …American Journal of Immunology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractMitochondrial Energy-Deficient Endophenotype in AutismJ. Jay Gargus, Faiqa ImtiazWhile evidence points to a multigenic etiology of most autism, the pathophysiology of the disorder has yet to be defined and the underlying genes and biochemical pathways they subserve remain unknown. Autism is considered to be influenced by a combination of various genetic, environmental and immunological factors; more recently, evidence has suggested that increased vulnerability to oxidative stress may be … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 11,507 accessesView PDFCite
Research ArticleOpen accessIn the abstractCancer may be caused by the Immune ReactionRichmond T. PrehnHormesis-like effects of immunity have been documented during tumor-growth experiments in mice, quantitatively large immune-reactions have inhibited while lesser quantities of the same specific immune-reactants have been stimulatory to the growth of implanted tumors. Likewise, carcinogenesis has been inhibited by a high quantities of immune reactants, but positively stimulated by lower levels of the same reactants. One observation suggests that … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,460 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Relationship Between Location and Prognosis in Brain-Stem TumorsN. Fayed, P. J. Modrego, J. EirasThe objective of this study was to establish a correlation between histopathology and radiological characteristics as well as location of brain stem tumors. Results of therapy were also analysed in relation to the radiological characteristics. Forty four patients were evaluated from a clinical and neuroradiological viewpoint (CT and MRI). In 14 of them we ruled out a surgical therapy. However … …OnLine Journal of Biological Sciences, Vol. 7, Issue 2 · 31 Dec 2007 · 6,839 accessesView PDFCite