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54 articles for “immunomodulator”
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Research ArticleOpen accessIn the abstractRegulation of Gene Expression by β-GlucansMary O. Huff, Carolyn M. Klingeβ-D-glucans are diverse polysaccharides derived from plant cell walls, fungi and bacteria. β-D-glucans are composed of D-glucose monomers linked by (1-3) β-glycosidic bonds with varying amounts of (1-6) or (1-4) linked side chains that bind cell surface receptors ultimately triggering changes in intracellular pathways and gene transcription. β-D-glucans have anti-viral, immunomodulatory and anti-cancer activities. This article reviews the current identity … …American Journal of Immunology, Vol. 13, Issue 1 · 12 Apr 2017 · 7,553 accessesView PDFCite
Review ArticleOpen accessIn the abstractPromising Effects of Beta-Glucans on Metabolism and on the Immune Responses: Review ArticleViviam de Oliveira Silva, Natália Oliveira de Moura, Larissa Jahnel Rodrigues de Oliveira et al.A public health issue, Diabetes mellitus, affects millions of people around the globe. Ingestion of foods with a low glycemic index - fiber-rich meals-such as beta-glucans, is increasing as an important alternative for diabetes control. These compounds act reducing parameters such as blood glucose, cholesterol and triglycerides, by decreasing the absorption of glucose and lipids by enterocytes and eventually promote … …American Journal of Immunology, Vol. 13, Issue 1 · 29 Mar 2017 · 12,684 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhancement of Immunological Responses by Dietary Arthrospira platensis and Possibility of Field Applications as Alternative to Antibiotics in Broiler ChickenShinsuke Katayama, Yumi Kayahara, Tomoko WatanabeArthrospira platensis is one of the candidates expected to replace antibiotics by its immunostimulatory effects in broiler industry, but the evaluation aimed at field applications is not enough. Here, we measured general immunological indicators such as specific antibody responses against sheep red blood cell and Brucella abortus, serum immunoglobulin concentrations and monocyte phagocytic capacity of broiler chickens, which assigned to … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 1 · 3 Mar 2016 · 7,086 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of two Different Culture Media on the Proliferation of Dental Pulp Stem Cells: Bovine Fetal Serum and Platelet LysateGiuseppe Cicero, Veena Nanda, Irene MartiniMesenchymal Stem Cells (MSCs) have been isolated from a variety of fetal and adult tissues and are considered an ideal source for cell-based therapy due to their unique properties such as multipotency and immunomodulatory functions. The aim of this work is to observe, analyze and investigate the morphology and proliferation of human dental pulp stem cells cultured in two different … …Current Research in Dentistry, Vol. 6, Issue 2 · 17 Sep 2015 · 7,461 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite
EditorialOpen accessIn the abstractANTIBIOTIC RESISTANCE: A FRIGHTENING HEALTH DILEMMARuchi Tiwari, Kuldeep DhamaByarugaba, D.K., 2004. Antimicrobial resistance in developing countries and responsible risk factors. Int. J. Antimicrob. Agents, 24: 105-110. DOI: 10.1016/j.ijantimicag.2004.02.015 Cirz, R.T., J.K. Chin, D.R. Andes, V. de Crécy-Lagard and W.A. Craig et al., 2005. Inhibition of mutation and combating the evolution of antibiotic resistance. PLoS Biol., 3: e176-e176. DOI: 10.1371/journal.pbio.0030176 Dhama, K., S. Chakraborty, Mahima, M.Y. Wani and A.K. … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 3 · 26 Sep 2014 · 10,774 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Cloning and Heterologous Expression of Human Interferon Alpha2b GeneI. Made Artika, Yemima Budirahardja, Anna Lucia EkowatiHuman alpha Interferons (hIFNα) have been shown to have antiviral, antiproliferative and immunomodulatory activities. The human interferon alpha2b (hIFNα2b), is one of the human interferon alpha2 sub variants, naturally synthesized as a polypeptide of 188 amino acid residues, the first 23 residues of which represents a signal peptide. In the present study, the hIFNα2b gene was expressed after being fused … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,835 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhysiological Effects of a Combination of Cinnulin with ProbioticsVetvicka Vaclav, Vetvickova JanaThe search for an optimal combination of natural immunomodulators led us to study the biological effects of the combination of a cinnamon extract Cinnulin PF and probiotic LactoSpore. We found that this combination has strong synergetic effects on phagocytosis and on regulation of cholesterol and blood sugar levels. In addition, the Cinnulin/LastoSpore combination also reduced intestinal damage in mouse model … …American Journal of Immunology, Vol. 9, Issue 4 · 2 Oct 2013 · 8,222 accessesView PDFCite
Research ArticleOpen accessIn the abstractCo-Inhibitory Molecule Programmed Death-1 and its Ligands: A New Alternative Therapy for Human Immunodeficiency Virus Infection?A. Leon-Flores, P. Del Rio, G. Reyes-TeranChronic viral infections are characterized by the up-regulation of a set of immunomodulatory receptors. The over-expression of co-inhibitory molecules on T cells leads to a dysfunctional T cell response with an "exhausted" phenotype. Programmed Death-1 (PD-1) is a molecule that exerts an inhibitory signal on the T cell receptor when it binds to the PD-L1 or PD-L2 ligands present on … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 28 Dec 2012 · 6,962 accessesView PDFCite
Research ArticleOpen accessIn the abstractLevamisole Enhances Cell-Mediated Immune Responses and Reduces Shedding of H9N2 Avian Influenza Virus in Japanese Quails (Coturnix coturnix japonica)Tahoora Shomali, Najmeh Mosleh, Arash AlaeddiniProblem statement: Regarding the role of Japanese quails (Coturnix coturnix japonica) in reassortment and spreading of avian influenza (AI) viruses and inadequate protection of vaccination in this species, the present study aimed to evaluate the effect of levamisole as an immunomodulatory agent on cell-mediated immunity (CMI), antibody responses and shedding of H9N2 AI virus in experimentally infected quails. Approach: On … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 6 Mar 2012 · 7,651 accessesView PDFCite