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Research ArticleOpen accessIn the abstractHormetic and Non-Hormetic Dose-Response Functions in Stress Effects on Memory and Synaptic Plasticity: Issues and MechanismsPhillip R. Zoladz, David M. DiamondOver a century of behavioral research has shown that stress can exert both positive and negative effects on memory. We have explored the idea that the complex effects of stress on learning and memory can be characterized by hormetic- and non-hormetic dose-response functions, in which stress may either stimulate or impair brain memory mechanisms, depending, in part, on the timing … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 8,188 accessesView PDFCite
Research ArticleOpen accessIn the abstractSuppression of Basal and Cytokine Induced Expression of MHC, ICAM 1 and B7 Markers on Mouse Lung Epithelial Cells Exposed to Diesel Exhaust ParticlesRajiv K. Saxena, Wanda Williams, M. Ian GilmourDiesel exhaust particles (DEP) constitute a significant component of airborne particulates in urban environment. Exposure to DEP is known to enhance susceptibility to viral and bacterial infections. We hypothesized that DEP could partially exert its effect on disease susceptibility by interfering with antigen presentation required for the generation of protective adaptive immune responses. MHC class I and class II molecules, … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,610 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Crude Aqueous Extract of Piper betle L. and its Antibacterial Effect Towards Streptococcus mutansT. Nalina, Z.H.A. RahimIn this study, the antimicrobial influence of crude aqueous extract of Piper betle L. on Streptococcus mutans (S. mutans) was investigated. The focus of the antimicrobial effects includes the ultrastructure and acid producing properties of S. mutans. Transmission electron microscopy (TEM) was used to determine the effect of the extract on the ultrastructure of S. mutans. Analysis of the effect … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 1 · 31 Mar 2007 · 13,465 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Case-Control Study of Effect of Opium Addiction on Myocardial InfarctionBehzad Azimzade-Sarwar, Gholamreza Yousefzade, Shahin NarooeyIschemic Heart Disease (IHD) and Myocardial Infarction (MI) are one of the most important disease which cause mortality and morbidity. Opioid peptides and exogenous opioid such as morphine are known to exert an important cardiovascular effect. To study effect of opium addiction to incidence of MI. A Case-Control study was designed in Kerman university. 150 patients with MI was admitted … …American Journal of Applied Sciences, Vol. 2, Issue 7 · 31 Jul 2005 · 7,211 accessesView PDFCite
Research ArticleOpen accessIn the abstractMachine Learning Based Prediction of Catch Yields in Small Scale FisheriesEpifelward Niño Olaivar Amora, Patrick D. CernaSmall-scale fisheries are critical for food security and livelihoods but increasingly face threats from overfishing and environmental change. This study employed machine learning to predict catch yields in Cogtong Bay, Philippines, using 3,478 records collected in 2020–2021 that included species, gear, location, season, and weather data. Models developed in Python with scikit-learn and XGBoost compared Random Forest (RF), Extreme Gradient … …Journal of Computer Science, Vol. 22, Issue 8 · 24 Aug 2026 · 1,117 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Comparative SCAPS-1D Study of Lead-Free CsSnCl₃-Based Perovskite SCs Employing Different ETLsRony Tota, Shak Mahmudul Hasan, Md. Morsalin et al.Cesium tin chloride (CsSnCl3) has drawn considerable interest as a non-toxic absorber candidate for next-generation photovoltaic devices, offering an attractive combination of affordability, thermal robustness, and competitive conversion performance suitable for clean-energy deployment. In the present work, the photovoltaic behaviour of CsSnCl₃-based SCs was numerically examined using the SCAPS-1D software. Three distinct device stacks were constructed by varying the ETL, … …American Journal of Engineering and Applied Sciences, Vol. 19, Issue 1 · 22 May 2026 · 1,746 accessesView PDFCite
Research ArticleOpen accessIn the abstractChanges in the Composition and Diversity of Pasture Grass Due to the Influence of Grazing in the Steppe Zone of Northern KazakhstanAliya Baitelenova, Balzhan Akhylbekova, Meisam Zargar et al.Overgrazing poses a serious threat to the sustainability of steppe pasturelands in Northern Kazakhstan, where intensifying livestock pressure drives significant changes in vegetation composition, species diversity, and soil fertility. This study investigated the effects of grazing intensity on pasture vegetation and chestnut soil properties in the Zhaksyn district of the Akmola region. Field surveys were conducted in July-August 2024 using … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 31 Mar 2026 · 1,344 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Atorvastatin on Oxidized Low-Density Lipoprotein-induced Proliferation, Apoptosis, and Matrix Metalloproteinase-9 Expression in Human MacrophagesBensheng Liu, Huifan Li, Yan Wang, Li ZhangAtorvastatin (ATV), an HMG-CoA reductase inhibitor, is utilized in the treatment of atherosclerotic diseases. Mononuclear Macrophages (MMs) are critical immune cells involved in atherosclerosis progression, participating in processes such as foam cell formation, cytokine secretion, and the development of fibrous cap and lipid core. To further elucidate the mechanism by which ATV exerts its therapeutic effects on atherosclerosis through the … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 18 Nov 2025 · 2,136 accessesView PDFCite
Research ArticleOpen accessIn the abstractUPLC-QTOF-MS/MS and Bioinformatics Association Analysis Reveals the Pharmacodynamic Flavonoids in Scutellaria barbata and the Underlying Anti-Colorectal Cancer MechanismYi-Jie Cheng, Xin-Yun Du et al.Colorectal Cancer (CRC) is one of the most common and deadly malignancies worldwide, with no safe and effective drugs. The flavonoid in Scutellaria Barbata D. Don (SB) showed a good therapeutic effect on CRC. However, the pharmacodynamic substances and underlying mechanisms have not been elucidated which limited its development and application. This study aimed to identify the main flavonoid in … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 14 Nov 2023 · 5,404 accessesView PDFCite
Research ArticleOpen accessIn the abstractExtraction Optimization and Antibacterial Property of Total Flavonoids from Zizania Latifolia Bracts and the Effect on Chilled Pork PreservationChen Pan, Shuyi Zhu, Na Niu et al.Zizania latifolia isa widely distributed aquatic vegetable, and its bracts are an agriculturalwaste with a large proportion. In this study, Total Flavonoids of Z. latifoliaBracts (TFZB) were extracted with Ultrasound-Assisted Enzymatic Extraction(UAEE) for the first time, and the extraction process was optimized usingResponse Surface Method (RSM), and compared with other methods. Then, theantibacterial activity of TFZB extracted with optimized UAEE … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 15 Sep 2022 · 6,013 accessesView PDFCite