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117 results for “antibodies”
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Research ArticleOpen accessIn the abstractPRODUCTION OF CROSS-REACTIVE AUTOANTIBODY BINDING TO BOVINE SERUM ALBUMIN IN THE D-GALACTOSE-INDUCED AGING MOUSE MODELJi-Hun Park, Tae-Saeng ChoiThe D-galactose (D-gal)-induced animal model, generated by repeated subcutaneous D-gal injections over approximately 6 weeks, has been frequently used for diabetes and aging research. However, little research has investigated the direct correlation between D-gal and autoantibody formation despite several reports on diabetes-and aging-related autoantibodies. The purpose of this study was to determine whether repetitive injection of D-gal can induce autoantibody … …American Journal of Immunology, Vol. 10, Issue 1 · 13 Jan 2014 · 7,040 accessesView PDFCite
Research ArticleOpen accessIn the abstractFlow Cytometry Baseline on Peripheral Leukocyte Cell Profiles for Dairy Goat KidsDarcy M. Fletcher, Megan B. Vogt, Hannah E. Pirner et al.Small ruminants, like goats, would make excellent animal models for not only infectious diseases in large ruminants but also analogous diseases in humans, such as human tuberculosis, Crohn’s disease, melioidosis and brucellosis. The main disadvantage for the small ruminant model is the lack of sufficient baseline data on normal, healthy goat kids. Furthermore, most reagents (antibodies and the like) were … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 26 Sep 2013 · 7,576 accessesView PDFCite
Research ArticleOpen accessIn the abstractSoluble CD59-Antigen Levels are Increased in Renal Disease PlasmaOluseyi Adewale VanderpuyeCluster of Differentiation antigen 59 (CD59) is a glycosyl phosphatidylinositol-linked protein that protects cells from damage by lytic terminal complexes of complement. Soluble forms of CD59 in serum have been little investigated in disease states. In the present study, by using a sandwich ELISA, reactivities with antibodies to CD59 were compared for sera and plasma from normal individuals and those … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 6,946 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeroprevalence of Toxoplasma gondii Among Schizophrenics at Hospital KajangLovetta Yatta Juanah, Juliana Jalaludin, Malina Osman, Zubaidah Jamil OsmanStudies have found a high seroprevalence of T. gondii in schizophrenia patients than controls. This case-control study was done to determine the serprevalence of Toxoplasma gondii and to identify its risk factors among schizophrenia patients at Hospital Kajang. Eighty-eight (88) schizophrenia patients and 88 non-psychiatric controls were examined for the presence of anti-Toxoplasma IgG and IgM antibodies by Enzyme Linked … …American Journal of Infectious Diseases, Vol. 9, Issue 1 · 20 Feb 2013 · 8,574 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Seroepidemiological Survey of Hantavirus in Ilheus CountyMarcos Lazaro Moreli, Vivaldo Gomes da Costa, Flavia Rubia ParizHantaviral diseases are infections caused by a group of viruses that belong to the genus hantavirus and the family Bunyaviridae. In Brazil, several cases of hantavirus have been detected with the use of serological methods including immunofluorescence and Enzyme-Linked Immunosorbent Assay (ELISA). To date, 1.573 cases have been reported in several states across the country with a fatality rate of … …Current Research in Virology, Vol. 1, Issue 1 · 30 Aug 2012 · 13,388 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeroprevalence of Neospora Caninum in Stray DogsGaredaghi YagoobProblem statement: To investigate anti-Neospora caninum antibodies in stray dogs living in Tabriz city, 100 blood samples were collected. Serum samples were screened for detection of anti-N. caninum IgG antibodies using Indirect Fluorescent Antibody Test (IFAT; ≥50). Antibodies were seen in 31 (31%) of 100 dogs. Approach: The IFAT antibody titers were as follows: 1:50 in 11 dogs, 1:100 in … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 3 · 5 Oct 2011 · 7,939 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatitis B and C Positivity in Various Categories of Human Immunodeficiency Virus Seropositive Individuals in a Regional STD Centre-an Eight-Year Evaluation of Trends and Risk FactorsSumathi Muralidhar, Manju Bala, Rakesh Kumar Jain et al.Problem statement: Among the various infections whose incidence has increased since the advent of HIV/AIDS, Hepatitis B and C stand out clearly. This is so because the routes of transmission of these infections are essentially the same as those of HIV/AIDS, making co-infections a common occurrence. The risk of infection for Hepatitis B and C is several times more than … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 6,926 accessesView PDFCite
Research ArticleOpen accessIn the abstractRal-Binding Protein is Required for the Maturation and Function of Dendritic CellsJozef Borvak, Mukesh Sahu, Varun Joy et al.Problem statement: Dendritic Cells (DCs) integrate responses of innate and adaptive immune system via transmitting pro-inflammatory and regulatory signals to naïve cells within draining lymph nodes. DCs have high capacity for endocytosis, both Clathrin-Dependent (CDE) and Caveolin-Dependent (CvDE). Approach: We have recently shown that ATP-hydrolysis by the multifunctional transporter protein RLIP76 is the primary determinant of the rate of CDE. … …American Journal of Immunology, Vol. 6, Issue 3 · 13 Sep 2010 · 8,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Cardiolipin Antibody in Acute Myocardial InfarctionAbdolreza Sotoodeh Jahromi, Mohammad Shojaie, Samira Dana, Abdoulhossain MadaniProblem statement: Myocardial infarction is the combined result of environmental and personal factors. Data concerning the relation between anti-Phospholipid (aPL) antibodies and myocardial infarction in subjects without evidence of overt autoimmune disease are conflicting. Anticardiolipin antibody is detected in various diseases like rheumatoid arthritis, systemic lupus erythematosus and anti-phospholipid antibody syndrome. The study of Anticardiolipin antibody in Acute Myocardial Infarction … …American Journal of Immunology, Vol. 6, Issue 1 · 31 Mar 2010 · 7,829 accessesView PDFCite
Research ArticleOpen accessIn the abstractSerological Evaluation of Brucella abortus S99 Lipopolysaccharide Extracted by an Optimized MethodAli Sharifat Salmani, Seyed Davar Siadat, Mohammad Reza Fallahian et al.Problem statement: Brucellosis is a globally found infectious disease and there is no licensed vaccine against human brucellosis. The present study carried-out to evaluate the potency of our modified extracted lipopolysaccharide (LPS) of B. abortus to elicit specific anti-Brucella antibodies in animal model (Rabbit) as a part of a candidate vaccine for brucellosis. Lipopolysaccharide is one of the main virulence … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 9,083 accessesView PDFCite