Research ArticleOpen accessIn the author namesExpression and Induction Optimization of Mucor Circinelloides Lipase in Escherichia ColiYueping Yang, Yao Zhang et al.Microbial lipases serve as versatile biocatalysts for modifying lipid substrates, enabling diverse biotechnological applications spanning food technology, renewable energy production, and pharmaceutical sectors. Genomic analysis of Mucor circinelloides WJ11 revealed multiple lipase-encoding genes, with WJ_23 successfully cloned and heterologously expressed in Escherichia coli. Since the lipase expression was mainly concentrated in the cell pellets, appropriate induction strategies had been investigated … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 13 Jun 2025 · 5,982 accessesView PDFCite
Research ArticleOpen accessIn the author namesIntegrated Analysis of Transcriptomic and Metabolomic Responses in Rice Resisting False SmutYanmin Yu, Haiying Liu, Hongtao Wu et al.Rice false smut, caused by Ustilaginoidea virens, is an important fungal disease that reduces both grain yield and quality. To dissect the molecular basis of resistance, we combined transcriptome sequencing and metabolite profiling in resistant and susceptible rice cultivars. Transcriptome sequencing revealed more than 8,500 genes with altered expression patterns after infection, while metabolite profiling detected over 700 significantly changed … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 27 Aug 2026 · 1,057 accessesView PDFCite
Research ArticleOpen accessIn the author namesMechanism of Mulberry's Effect on Intestinal Flora and MotilityHuizhen Zhao, Shijing Xie, Yuwen Li et al.Studies have indicated that mulberry consumption promotes intestinal motility and alleviates constipation, but the specific mechanism remains unclear. This study adopted a constipation mouse model to empirically analyze the effects of mulberry on intestinal motility, gut microbiota composition, and neurotransmitter levels, aiming to elucidate its mechanism of action. Key findings are as follows: 1) Compared with the model group, the … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 1,189 accessesView PDFCite
Research ArticleOpen accessIn the author namesPreparation and Properties Study of PCM@ECD BilayerYan Zhao, Heng Zhang, Yanfei Zhao et al.This study reports the fabrication of a core-shell active bilayer membrane (PCM@ECD) via a combined tape-casting and layer-transfer methodology. The inner core layer comprised Pectin-Chitosan (PC) microcapsules, synthesized by complex coacervation, encapsulating Orange Peel Essential Oil (OPEOM) with an embedding efficiency of 83.08%. The outer shell layer consisted of Ethyl Cellulose (EC) doped with zinc-doped carbon dots (Zn-CDs, average size: … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 8 May 2026 · 1,600 accessesView PDFCite
Research ArticleOpen accessIn the author namesExploring the Relationship Between Skin Barrier Function, Sensitivity, and Repair MechanismsXiaoqing Yan, Yusong Shi, Jiguang YangFor healthy skin, the skin's barrier function must remain maintained. Many different molecular while immunological signaling mechanisms are involved in skin barrier control. The control of a healthy skin barrier, particularly acid mantle maintenance and proper amounts of ceramides, may help dermatologists develop remedies for skin barrier disruption disorders. In contrast, new medicines could focus on signaling pathways to offer … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,893 accessesView PDFCite
Research ArticleOpen accessIn the author namesEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite
Research ArticleOpen accessIn the author namesCPF-Net: Cross-modal CT and Pathology Guided Feature Learning for CT-based Lung Cancer Subtype ClassificationPeizhi Tan, Debiao YanAccurate classification of lung cancer subtypes from CT images remains challenging due to the subtle radiological differences between adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC). We propose CPF-Net, a deep learning framework that integrates CT and pathological information through a Linear Spatial Reduction Attention (LSRA) module. The framework processes whole slide images using a modified CTransPath architecture for pathological feature … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 23 Jan 2026 · 1,856 accessesView PDFCite