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57 results for “Type I Resistance”
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Research ArticleOpen accessIn the abstractRetinoids Chemosensitize Ovarian Cancer Cell Lines to Cisplatin Independent of Nuclear Receptors and p53Suresh Guruswamy, Doris M. BenbrookTreatment of ovarian cancer with cisplatin-based chemotherapy is highly toxic and is often followed by cancer recurrence. Repeated treatments with cisplatin frequently result in the development of resistance to this drug. Drugs with low toxicity that could enhance the tumor cell killing effects of cisplatin could potentially reduce the toxicity and enhance the efficacy of cisplatin. The mechanism of cell … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,958 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment of a Wear Map for the Sliding and Rotational Wear behavior of ShaftsAl-mahasne Mayas MohammadThis study was an attempt to study the wear calculation method for rotating shaft in the friction couple type shaft-cuff in conditions of oiling in high dusty environment. The size and quantity of abrasive particles that go into the clearance between friction surfaces, definition of the pressure including the load in conjugate that is given by the cuff spring as … …American Journal of Applied Sciences, Vol. 3, Issue 12 · 31 Dec 2006 · 6,913 accessesView PDFCite
Research ArticleOpen accessIn the abstractAbout Glassy Amorphous Metal InjectionRaffaella Aversa, Relly Victoria Petrescu, Antonio Apicella et al.The paper aims to present studies on the melt flow, melting and rheology of melting in a super-cooled metastable liquid metal, which is injection molded, of the Zr44-Ti11-Cu10-Ni10-Be25 alloy, which can induce selective crystallization. In this process, high Be-velocities were observed, Cu and Ni atoms that crystallized differently in superficial bulk metallic bulk liquids. It wants to highlight and analyze … …International Journal of Structural Glass and Advanced Materials Research, Vol. 2, Issue 1 · 22 Jan 2018 · 7,438 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Modern FlightRelly Victoria Petrescu, Florian Ion Tiberiu Petrescu, Antonio Apicella et al.A modern flight involves both a great flight quality and high safety throughout. You can’t speak of a quality of flight today unless it provides increased comfort to all passengers in full safety and relaxation. Regardless of the aircraft design type, a minimum level of comfort is required in the passenger cabin so that they feel safe, comfortable, quiet, plus … …Journal of Aircraft and Spacecraft Technology, Vol. 1, Issue 4 · 19 Oct 2017 · 8,318 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Different Environments on Reinforcement Concrete CorrosionMohammed Thalji Awwad, Omar Asad AhmadThis research focuses on various forms of steel bar corrosion located in different environments and the factors affecting the corrosion process, both the external (surrounding environment around concrete elements) and the internal environment (concrete itself), as well as on the investigations and tests for this type of damage, in order to develop measurements and recommendations that will reduce harmful investment … …American Journal of Environmental Sciences, Vol. 13, Issue 4 · 15 Sep 2017 · 7,805 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy of Heat-Treated Steel and Related ApplicationsShu-Ping Chang, Ming-Chen Chen, Jyh-Dong LinNumerous studies conducted after the 921 earthquake in Taiwan in 1999 have reported that because heat-treated steel features relatively unstable mechanics properties, using such steel in welding, bar splicing, or as thread-cutting components in structures may result in lack of resistance to seismic activity. However, nondestructive testing methods that can be used to identify the type of steel delivered to … …American Journal of Engineering and Applied Sciences, Vol. 8, Issue 4 · 30 Oct 2015 · 7,543 accessesView PDFCite
Research ArticleOpen accessIn the abstractK121Q Polymorphism of the ENPP1 Gene is Related to Acute Coronary Syndrome in Ukrainian Patients with Normal but not Enhanced Body Mass IndexInna A. Rozumenko, Victoria Y. Garbusova, Yurij A. Ataman et al.Ectonucleotide Pyrophosphatase Phosphodiesterase 1 (ENPP1) is a class II membrane glycoprotein with two unrelated properties: It can hydrolyze extracellular nucleotides and downregulate insulin receptor signaling. The present study was carried out to investigate whether common single-nucleotide polymorphism K121Q (rs1044498) of the ENPP1 gene is associated with Acute Coronary Syndrome (ACS) in the representatives of Ukrainian population and to assess if … …OnLine Journal of Biological Sciences, Vol. 14, Issue 4 · 15 Jan 2015 · 7,345 accessesView PDFCite
Research ArticleOpen accessIn the abstractINHIBITORY ACTIVITY OF POTENTOX AGAINST DNA GYRASE OF ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiDNA gyrase, a type II topoisomerase catalyzes the supercoiling of relaxed closed circular DNA. In this report we evaluated the in vitro inhibitory effect of non antibiotic adjuvant compounds disodium edetate and sodium citrate against supercoiling activity of bacterial DNA gyrase. Further, we assessed the effect of different drugs alone and in combination with one or more adjuvants in overcoming … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 8 Feb 2014 · 7,288 accessesView PDFCite
Research ArticleOpen accessIn the abstractDEVELOPMENT OF A PROXIMAL MACHINE VISION SYSTEM FOR OFF-SEASON WEED MAPPING IN BROADACRE NO-TILLAGE FALLOWSH. Liu, C. Saunders, S. H. LeeWeeds are among the most significant and costly environmental threats in Australian agriculture. Weeds compete with crop plants for moisture, nutrients and sunlight and can have a detrimental impact on crop yields and quality if uncontrolled. The distribution, size, density and species of the weeds are often heterogeneous in the cropping land. Instead of uniformly spray the same type of … …Journal of Computer Science, Vol. 9, Issue 12 · 26 Nov 2013 · 7,233 accessesView PDFCite