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248 results for “Simulations”
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Research ArticleOpen accessIn the abstractUPLC-Q-Exactive Orbitrap-MS Analysis of Anchusa italica Retz. Flowers: Molecular Docking, Dynamics Modeling, and Pharmacokinetics for Cardiovascular DiseaseLinyang Wang, Yan Chen, Ainiwaer Aikemu, Shuge TianThis study builds on prior UPLC-Q-Exactive Orbit rap-MS analyses of Anchusa italica Retz. Flowers (Airfs) to explore their anti-cardiovascular mechanis·ms and key bioactive markers. UPLC-Q-Exactive Orbitrap-MS identified 30 major compounds, including polyphenols and flavonoids with strong antioxidant activity. The potential active ingredients were then screened using Lipinski's rule of five, and a network pharmacology method was employed to construct an … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Oct 2025 · 2,599 accessesView PDFCite
Research ArticleOpen accessIn the abstractMethodology of the Development of Production Digital Twins Using a Simulation ExperimentSnježana Križanić, Neven VrčekThe simulation experiment evaluates whether the business process model accurately replicates real-world operations and whether the digital twin functions in real-time. A digital twin of a production business process is a virtual representation of its real-world counterpart. Its aim is to monitor the execution of the actual production business process in order to detect irregularities and production downtimes early and … …Journal of Computer Science, Vol. 21, Issue 6 · 13 Jun 2025 · 4,805 accessesView PDFCite
Research ArticleOpen accessIn the abstractHybrid Optimization to Trust Enhanced Secure Routing Optimization with IABC and CGWAA for MANETYuvaraja Panneer Selvam, Suganthi PerumalRouting in Mobile Ad Hoc Networks (MANET) presents significant challenges due to the dynamic nature of network topology. Optimal route selection and efficient route discovery are matched by effective routing in MANET. This study proposes a Hybrid Optimization to Trust-Enhanced Secure Routing Optimization (HO-TESRO) designed to address these challenges in IoT environments by integrating metrics such as link stability, bandwidth, … …Journal of Computer Science, Vol. 21, Issue 4 · 19 Mar 2025 · 4,983 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn silico and in vitro Structural Analysis on the Interaction of Calmodulin and Calmodulin-Binding Motif of FKBP35 from Plasmodium knowlesiSazlinawatie Aladin, Cahyo Budiman et al.FK506-binding protein 35 (FKBP35) is a peptidyl-prolyl cis-trans isomerase found in Plasmodium knowlesi, a zoonotic malaria parasite responsible for concerning cases of malaria infection in East Malaysia. This protein contains a segment known as the calmodulin-binding motif (Pk-CBM), which is predicted to facilitate interaction with calmodulin from P. knowlesi (Pk-CaM). Although this interaction is considered promising for future antimalarial drug … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 10 Mar 2025 · 4,846 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of NaCl on the Stability of Ab3 Lipase from Sphingobacterium sp. that Co-Expressed with LEA K Using In silico ApproachIbrahim Muhammad et al.This study explores how sodium chloride (NaCl) influences the binding affinity and stability of the Ab3 lipase-LEA K complex when interacting with olive oil, using molecular docking techniques. The docking simulations, conducted with AutoDock Vina, reveal that the presence of NaCl significantly enhances the binding affinity of the enzyme-substrate complex, increasing it from-6.55 kcal/mol in the absence of salt to-7.81 … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 9 Mar 2025 · 5,599 accessesView PDFCite
Research ArticleOpen accessIn the abstractSecuring IoT Networks: Multi-Attack Detection of RPL Routing Threats Using Deep LearningAyoub Krari, Abdelmajid Hajami, Ayoub Toubi, Marouane Ait SaidThe growing frequency of cyber threats in Internet of Things (IoT) networks, including attacks on RPL routing, requires the creation of strong detection systems to safeguard network integrity and provide dependable communication. This study is driven by the pressing necessity to tackle the security weaknesses in IoT networks, where threats such as black holes, version number alteration, DIS flooding, and … …Journal of Computer Science, Vol. 21, Issue 4 · 6 Mar 2025 · 5,397 accessesView PDFCite
Research ArticleOpen accessIn the abstractNumerical Investigation of the Impact of Punch Speed on the Deep Drawing of Square Aluminum Sheet Using Finite Element MethodEhsan Hedayati, Arefeh Hedayati, Mohammad Vahedi, Shirko FaroughiThis study examines the Deep Drawing Process (DDP) of square aluminum sheets, emphasizing its applications across various industries, including medical devices. The process is simulated using ABAQUS finite element software, analyzing the effects of parameters like punch speed and friction on the final results. One of the important aspects of this study is the use of the Forming Limit Diagram … …American Journal of Engineering and Applied Sciences, Vol. 18, Issue 1 · 6 Feb 2025 · 8,712 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of the Operation of DC Interconnected Households PV under Weather ConditionsGilbert Ngoma, Maryse Dadina Nkoua Ngavouka et al.Installing Photovoltaic (PV) systems is becoming a viable solution for rural areas, with an innovative approach consisting of interconnecting autonomous PV-powered households. This study analyses the performance of interconnected autonomous PV households under different weather conditions using the Matlab Simulink R2016a software. Over and above this interconnection analysis, in this study, a new mathematical model to predict PV power is … …American Journal of Engineering and Applied Sciences, Vol. 18, Issue 1 · 4 Jan 2025 · 6,207 accessesView PDFCite
Research ArticleOpen accessIn the abstractPerformance Evaluation of UE Location Techniques in LTE NetworksYahia Zakaria, Lubomir IvanekThe goal of this research is to evaluate the location accuracy of User Equipment (UE) in Long Term Evolution (LTE) networks which depends on the timing advance parameters. The ability to locate the subscribers through the network is considered as a significant factor in wireless communication systems. The main method to geolocation based on specified distances from many base stations … …American Journal of Applied Sciences, Vol. 14, Issue 1 · 5 Jan 2017 · 8,028 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimal Control of a Malaria Transmission Model with Saturated IncidencePerpetual Appiah, Henry Amankwah, Francis BenyahWe present a vector-host deterministic model for the transmission and control of malaria, using prevention and treatment as controls. A novel addition to our model is a new prevention function that highlights the role of prevention in reducing vector populations; an essential arsenal in the fight against malaria. Another innovation is the use of a novel treatment function, which reflects … …Journal of Mathematics and Statistics, Vol. 20, Issue 1 · 29 Feb 2024 · 5,894 accessesView PDFCite