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189 results for “Reactive”
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Research ArticleOpen accessIn the keywordsRADIOSENSITIZATION OF CANCER STEM CELLS: TARGETING TGFβ, NOTCH OR TELOMERASE TO IMPROVE TUMOR RESPONSE O RADIOTHERAPYIgnacio Fernandez-GarciaRadiation resistant cancer stem cells are the main reason for treatment failure and tumor recurrence after cancer radiotherapy. Increasing biological evidences demonstrate that these cells possess the capacity to repair radiation induced DNA damage, protect themselves from radiation derived reactive oxygen species, survive and proliferate after several fractions of radiotherapy and finally, repopulate the heterogeneity of the tumor. Thus, targeting … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Jul 2014 · 7,459 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEXPOSURE TO SWINE HOUSING DUST MODULATES MACROPHAGE MORPHOLOGY AND FUNCTIONRuth J. Pender, Radiah C. Minor, Steven L. Hurley et al.Swine Confinement Facility (SCF) dust consists of a complex mixture of feed grain particles, bacterial components, organic particulates and gases. When these particles are inhaled they deposit along the respiratory tract and mediate respiratory symptoms and disease in swine farmers and facility workers. Macrophages ingest and eliminate microbes and debris under chronic conditions; however, the role of macrophages in agricultural-related … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,606 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Role of Inflammation in Development and Therapy of Malignant MesotheliomaArti Shukla, Jill MillerMalignant Mesothelioma (MM) is an asbestos related malignancy with a poor prognosis and limited therapeutic approaches. The pathogenesis of MM has been linked to asbestos induced inflammation. Asbestos exposure results in reactive oxygen species generation, infiltration of inflammatory cells and prolonged release of multiple cytokines, oxidants and growth factors. The role of inflammation in MM has led to the evaluation … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 7,437 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRELATIONSHIPS AMONG INDICATORS OF FITNESS, FATNESS AND CARDIOVASCULAR DISEASE RISK FACTORS IN ADOLESCENTSRobert Malina, Stephen-Mark Cooper, John Young et al.In adults, fatness and low cardiorespiratory fitness are associated with a higher prevalence of chronic disease risk and mortality. The association between measures of physical fitness and fatness upon cardiovascular risk in youth, however, is less clear. The effects of adiposity and physical fitness upon cardiovascular disease risk factors in youth are receiving increasing attention but studies that have examined … …OnLine Journal of Biological Sciences, Vol. 12, Issue 3 · 7 Aug 2012 · 8,114 accessesView PDFCite
Research ArticleOpen accessIn the keywordsQuercetin in Dimethyl Benzanthracene Induced Breast Cancer in RatsNatla Sashidhar Reddy, Parthasarathy Nirmala, Natesan Chidambaram, Pammi Ashok kumarProblem statement: Vincristine a commonly used anticancer agent in the treatment of breast cancer results in serious adverse effects like teratogenicity, neurotoxicity and carcinogenicity on long term use. Drug resistance is also a common problem encountered with vincristine. Hence the effect of flavonol quercetin, a known antioxidant with no known documented adverse effect was tried in treatment of DMBA induced … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 30 Jul 2012 · 8,138 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAntioxidant and Photosynthetic Responses in Plants Under Boron Toxicity: A ReviewLucia Guidi, Alberto Pardossi, Elena Degl’Innocenti, Marco LandiBoron (B) is a micronutrient that has long been known essential not only for plants and animals. Otherwise, in crop plants the range of B concentration from essentiality to toxicity appears extremely narrow. Although B deficiency has been well investigated, during recent years many researchers have also investigated boron toxicity effects, making progress in the comprehension of boron transport within … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 5 Jul 2012 · 12,762 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOligoglucans as Elicitors of an Enzymatic Antioxidant System in Zucchini Squash (Cucurbita pepo L.) Seedlings at Low TemperatureAbel Ceron-Garcia, Gustavo Adolfo Gonzalez-Aguilar, Irasema Vargas-Arispuro et al.Abstract: Problem statement: Non-controlled low temperatures affect physiological and biochemical processes leading to Reactive Oxygen Species (ROS) accumulation in plants, which normally are stabilized by the antioxidant system. Superoxide Dismutase (SOD), Ascorbate Peroxidase (APX) and Catalase (CAT) are the most important ROS-detoxification enzymes in stressed plants. Approach: The activity of these enzymes were examined in response to fungal Oligoglucans (OG) … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 1 · 15 Dec 2010 · 8,306 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPreliminary Tests Concerning Zero-Valent Iron Efficiency in Inorganic Pollutants RemediationSilvia Fiore, Maria Chiara ZanettiProblem statement: This study was aimed to a preliminary evaluation of the applicability of granular Zero-Valent Iron (ZVI) to the on site remediation of groundwater polluted by inorganic contaminants by means of a Permeable Reactive Barrier (PRB). A particular interest was devoted to groundwater impacted by Acid Mine Drainage (AMD) that was caused by the oxidation of metal sulphide minerals … …American Journal of Environmental Sciences, Vol. 5, Issue 4 · 31 Aug 2009 · 6,789 accessesView PDFCite
Research ArticleOpen accessIn the keywordsVoltage Collapse Risk Associated to Under-Voltage Capacitive Compensation in Electric Power System OperationHeraldo Silveira Barbuy, Alexandre Rocco, Luiz Augusto Pereira Fernandes, Geraldo Caixeta GuimarãesProblem statement: In the operation of an Electric Power System (EPS), it has been usual to provide reactive power injection to avoid an under-voltage bus condition. In some situations an adequate voltage profile will not be a guarantee against Voltage Collapses (VCs) that may cause blackouts as seen in many occurrences around the world. The repeatedly injection of reactive power … …American Journal of Applied Sciences, Vol. 6, Issue 4 · 30 Apr 2009 · 7,253 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHormesis and Exercise: How the Cell Copes with Oxidative StressLi Li Ji, Zsolt Radak, Sataro GotoContraction-induced production of reactive oxygen and nitrogen species has been shown to cause oxidative stress to skeletal muscle, heart and other organs. As an adaptive response, muscle antioxidant defense systems are upregulated in response to exercise to restore intracellular prooxidantantioxidant homeostasis. Thus, both young and old animals and humans involved in regular exercise have shown reduced oxidative damage during acute … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,817 accessesView PDFCite