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59 results for “Polymorphisms”
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Research ArticleOpen accessIn the abstractComparative Analysis of the Complete Chloroplast Genome of the Alloplasmic Sunflower (Helianthus L.) Lines with Various CMS TypesKirill Azarin, Maxim Makarenko, Alexander Usatov et al.The complete chloroplast genomes of sunflower fertile line HA89 and isonuclear CMS lines with four different cytoplasmic backgrounds (PET1, PET2, ANN2 and MAX) were sequenced. A total of 451 polymorphic sites, with including 58 SSRs, 317 SNPs and 76 microindels were revealed between the fertile and CMS cytotypes. Among the alloplasmic male-sterile lines, cpDNA of CMS-MAX had the largest number … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 1 · 2 Mar 2018 · 9,415 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Association of Early Pregnancy Loss with Polymorphism in Xenobiotics Detoxification GenesElena Vladimirovna Mashkina, Konstantin Nikolaevich Saraev, Elena Viktorovna Butenko et al.Pregnancy loss and other pregnancy complication can be connected with environmental and lifestyle risk factor, among which effect of chemical compounds is the strongest. Effects of xenobiotics can be modified by allele variants of xenobiotic detoxification enzymes phase I or II. A total of 71 women with early pregnancy loss and 101 control patients were examined by a case-control methodology. … …American Journal of Applied Sciences, Vol. 12, Issue 3 · 6 May 2015 · 7,032 accessesView PDFCite
Research ArticleOpen accessIn the abstractLEUKOTRIENE C4 SYNTHASE AND LEUKOTRIENE RECEPTOR-1 GENES POLYMORPHISM AMONG ATOPIC ASTHMATIC PATIENTSHeba M. Kadry, Amal H. Atta, Mostafa K. Sultan, Nagwa A. El-BazAsthma is a complex polygenic disease in which Cysteinyl Leukotrienes (Cys-LTs) are a potential risk factors causing airway inflammation and remodeling, which are characteristics of asthma. The polymorphisms in the leukotriene C4 synthase -444A/C and cysteinyl leukotriene receptor1 927 T/C genes has been implicated in susceptibility to asthma. The objective of this study was to analyse two different polymorphisms, LTC4S-444 … …American Journal of Immunology, Vol. 10, Issue 2 · 5 May 2014 · 7,379 accessesView PDFCite
Research ArticleOpen accessIn the abstractRANDOMLY AMPLIFIED POLYMORPHIC DNA-A BRIEF REVIEWNandani Kumari, Saroj Kumar ThakurRAPD is a PCR based technique which involves the use of single arbitrary short primers (8-12 nucleotides), resulting in the amplification of many discrete DNA. The segments of DNA that are amplified are random. The technique was developed independently by two different laboratories and called as RAPD and AP-PCR (Arbitrary Primed PCR). This procedure detects nucleotide sequence polymorphisms in a … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 1 · 2 Jan 2014 · 17,258 accessesView PDFCite
Research ArticleOpen accessIn the abstractCTLA-4 Gene Polymorphism in Relation to Thyroid Disorders in Patients with Chronic Hepatitis C Under Interferon Alpha TherapySalwa M. Abo El-Khair, Abd El-Hameed A. Metwali, Mohamed Abd El-Maksoud, Tarek BesheerThyroid autoimmunity and dysfunction have reported as side effects of interferon-α treatment. The CT60 and exon 1+49 A/G polymorphisms in the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) gene have linked to susceptibility to autoimmune disease. The aim of this research was to analyze the frequencies of CTLA-4 CT60 and +49 A/G polymorphisms and evaluate both polymorphisms as indicators of thyroid disorder … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 3 · 20 Sep 2012 · 7,582 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation of DNA Polymorphism at the Apolipoprotein B-100 Gene Locus with Plasma Lipid Concentration and Coronary Artery Disease among North IndiansVivek Pratap Singh, V. Ramesh, Sonal Somvanshi et al.The aim of this study was to investigate the association between apolipoprotein B gene polymorphisms and coronary artery disease and lipid levels in north Indians. Two hundred patients of angiographically proven atherosclerotic CAD and two hundred age and sex matched control subjects were included in the study. Serum lipids including cholesterol, triglycerides, HDL, LDL, VLDL and ApoB were analyzed. PCR … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 7,892 accessesView PDFCite
Research ArticleOpen accessIn the abstractSSR Analysis of Maternal and Paternal Lines Selected in the Don Region (Russia)N. V. Markin, A. V. Usatov, V. N. Vasilenko et al.Evaluation of DNA polymorphisms of breeding material of sunflower from L.A. Zhdanov Don Experimental Station of oil Crops of V.S. Pustovoit All-Russian Research Institute of Oil Crops represented by 17 maternal (CMS) lines and 12 paternal (Rf) lines was conducted. There were identified 35 allelic variants of CMS lines and 42 allelic variants of Rf lines with use of 11 … …American Journal of Agricultural and Biological Sciences, Vol. 11, Issue 1 · 16 Jan 2016 · 7,555 accessesView PDFCite
Research ArticleOpen accessIn the abstractK121Q Polymorphism of the ENPP1 Gene is Related to Acute Coronary Syndrome in Ukrainian Patients with Normal but not Enhanced Body Mass IndexInna A. Rozumenko, Victoria Y. Garbusova, Yurij A. Ataman et al.Ectonucleotide Pyrophosphatase Phosphodiesterase 1 (ENPP1) is a class II membrane glycoprotein with two unrelated properties: It can hydrolyze extracellular nucleotides and downregulate insulin receptor signaling. The present study was carried out to investigate whether common single-nucleotide polymorphism K121Q (rs1044498) of the ENPP1 gene is associated with Acute Coronary Syndrome (ACS) in the representatives of Ukrainian population and to assess if … …OnLine Journal of Biological Sciences, Vol. 14, Issue 4 · 15 Jan 2015 · 7,345 accessesView PDFCite
Research ArticleOpen accessIn the abstractHEAVY METAL ANALYSIS IN RED OAK (QUERCUS RUBRA) POPULATIONS FROM A MINING REGION IN NORTHERN ONTARIO (CANADA): EFFECT OF SOIL LIMING AND ANALYSIS OF GENETIC VARIATIONAnh Tran, K. K. Nkongolo, M. Mehes-Smith et al.Understanding the dynamic of metals in soil and plants and population diversity in Northern Ontario is essential in determining progress toward ecosystem sustainability in reclaimed sites. The objectives of the present study were to assess the levels of metal content in soils and their accumulation in red oak plants from limed and unlimed sites. Genetic variation in red oak populations … …American Journal of Environmental Sciences, Vol. 10, Issue 4 · 25 Jun 2014 · 7,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractStructural Consequences of the Polymorphism Q223R in the Human Leptin Receptor: A Molecular Dynamics StudyJonathan P. Carrillo-Vázquez, Brenda Chimal-Vega, Beatriz Zamora-López et al.Leptin Receptor (LEPR) is a component of a signaling pathway related to appetite and energy expenditure. Single Nucleotide Polymorphisms (SNP) of Leptin receptor gene (lepr) have been proposed as possible modulator of adipose tissue and body weight. The main phenomenological consequence reported of these SNPs is the modulation of the LEP-LEPR interaction promoting the weight gain. Particularly, Q223R polymorphism has … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 3 · 23 Sep 2013 · 7,835 accessesView PDFCite