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191 articles for “Pathway”
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Research ArticleOpen accessIn the abstractComputational Prediction of Diabetic Nephropathy-Associated Comorbidities and Their Key Genes by Analyzing RNA-Seq DataChaity Paul, Md. Ashiq Uddin, Rupa Dey et al.Diabetic Nephropathy (DN) is a complex health condition that leads to various kidney diseases. According to the World Health Organization, over 2 million deaths have been reported due to diabetes and diabetes related kidney diseases in 2021. And at the recent 78th World Health Assembly, chronic kidney disease was reported to be one of the most common diabetes-related complications, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 19 May 2026 · 1,667 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Chain Mediating Role of Technology Self-Efficacy and Attitudes in Online Learning EnvironmentsJie Gao, Dolores D. Borras, Beverly T. CaigaThis study investigates the mediating role of technology self-efficacy and attitudes in online learning environments among university students. Specifically, we examined how students' technology self-efficacy, attitudes toward online learning, and perceptions of course appropriateness influence online learning outcomes. Data were collected via questionnaire survey from students enrolled in public and private universities (N = [specify number]). Structural equation modeling with … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 16 Feb 2026 · 1,601 accessesView PDFCite
Research ArticleOpen accessIn the abstractDecoding Lung Cancer: PLAU as a Critical Driver and Diagnostic MarkerStanley Cho, Min Gyeong KimLung cancer remains a leading cause of cancer-related mortality, and understanding its underlying molecular mechanisms is critical for developing targeted therapies. We developed a novel tool called the Transcriptome-TCGA Integration (TTI), which combines in vitro transcriptome data with clinical datasets from the Cancer Genome Atlas (TCGA). TTI allows for the identification of key genes and pathways involved in lung cancer, … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,424 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacterization of Fructan Content from Stem Juices of Different Varieties of Agave Atrovirens, Traditionally Used for the Production of Pulque. Production of a Sweetening Syrup by Chemical and Enzymatic ProcessingKaren Gott-Bravo, Arnulfo Pluma-Pluma, Victor Eric López-López et al.Agave atrovirens, the hardiest species of Agave in Mexico, thrives in tough, infertile soils and extreme temperatures across a wide range of altitudes, particularly in impoverished rural areas of Central and Northern Mexico. Its potential for agroindustrial use could offer a pathway to social and economic prosperity for many communities. Traditionally, A. atrovirens is tapped for its sap, known as … …American Journal of Agricultural and Biological Sciences, Vol. 19, Issue 1 · 4 Mar 2025 · 7,670 accessesView PDFCite
Review ArticleOpen accessIn the abstractEconomic Theory and Machine Learning Integration in Asset Pricing and Portfolio Optimization: A Bibliometric Analysis and Conceptual FrameworkPatrick Kevin Aritonang, Sudarso Kaderi Wiryono, Taufik FaturohmanThe integration of Machine Learning (ML) with economic theory has transformed financial market analysis, particularly in asset pricing and portfolio optimization. This study synthesizes existing research, identifies gaps and elucidates ML's impact on enhancing economic models and strategies through a Systematic Literature Review (SLR) of 401 relevant documents using bibliometric methodology and VOS viewer. Results show an increasing trend in … …Journal of Computer Science, Vol. 20, Issue 10 · 7 Aug 2024 · 5,715 accessesView PDFCite
Research ArticleOpen accessIn the abstractCross Talk between Iron Regulatory Proteins and Proinflammatory Molecules in Ovarian Cancer Patients Based on Menopausal StatusHaritha Padannapurath Manoj, Sudha Kuthethur, Reshma Kumarchandra et al.Micronutrient iron is postulated to contribute to the initiation of cancer mainly by the formation of Reactive Oxygen Species (ROS), the key signaling molecules of inflammatory reactions. Iron may also cause elevation of MMP9, a gelatinase responsible for remodeling extracellular matrix in cancer cells through the ROS pathway. Estrogen the hormone which decreases markedly in post menopause is also known … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 31 May 2024 · 4,491 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,947 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of the Fermentation Medium of Streptomyces ahygroscopicus ΔnysB, a Tetramycin Producing Strain, by the Response Surface MethodXiao Wang, Yao Dong, Xin Chen et al.Streptomyces ahygroscopicus ΔnysB is a genetically engineered strain that produces tetramycin by blocking the competition nystatin pathway. Response Surface Methodology (RSM) was used to optimize its fermentation medium composition. Taking the yield of tetramycin as the response value, the effects of corn starch, glucose, fish peptone, (NH4)2SO4, KH2PO4, and CH3COONa on the yield of tetramycin were investigated by the Plackett-Burman … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 9 Apr 2024 · 5,319 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Enzymatic Role of Lipid Metabolism in Yarrowia lipolytica Grown on GlycerolRuixue Wang, Feifei Xin, Yufei Chang et al.More attention has been paid to the production of commercial fatty acids by microbial fermentation. The basic biochemistry of lipid accumulation in oleaginous microorganisms under nitrogen limitation has been extensively studied. As an oleaginous microorganism, Yarrowia lipolytica can produce fatty acid-derived biofuels and biochemicals. However, the response of the enzymes in Y. lipolytica to glycerol remains unclear. Therefore, we aimed … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 2 · 17 Apr 2023 · 6,309 accessesView PDFCite
Research ArticleOpen accessIn the abstractLumbricus rubellus Protein Fraction DLBS1033N Increases Nerve Growth Factor Expression via Tyrosine Kinase ActivationAgung Heru Karsono, Raymond Rubianto Tjandrawinata, Maggy Thenawidjaja SuhartonoNerve injury occurred due to mechanical, thermal, chemical, or ischemic factors. Nerve regeneration is needed for recovery. Schwann cell proliferation and differentiation are important factors in the nerve regeneration process. Schwann cells release neurotrophins in the nerve regeneration process. In this study, Lumbricus rubellus protein fraction DLBS1033N was used as therapeutic protein candidate for nerve regeneration treatments. DLBS1033N treatments promoted … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 1 · 7 Feb 2018 · 9,407 accessesView PDFCite