43 articles for “Parasites”

Research ArticleOpen accessIn the abstractRole of Biopterin Transporter (BT1) Gene on Growth and Infectivity of LeishmaniaManju Jain, Vandana S. Dole, Peter J. Myler et al.Leishmania are known to be auxotrophic for pteridines that are known to play a critical role in the parasites survival. In the present work the role of biopterin transporter in the growth of the parasite and infectivity in to macrophages has been worked out. The role of biopterin transporter in the susceptibility of Leishmania to antimonial compounds has also been … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 7,038 accessesView PDF Cite

Research ArticleOpen accessIn the abstractFunctional Characterization of Neutrophils from Nine-Banded Armadillos (Dasypus novemcicntus; Edentata, Dasypodidae) Infected with MicrofilariaeMarcela López-Hurtado, Fernando M. Guerra-InfanteThe neutrophils from uninfected armadillos have adequate phagocytic and bacteriocidal activity, but diminished chemotactic activity. However, endocytic activity from armadillo neutrophils infected with bacteria, parasites or viruses is unknown. This report shows that neutrophils from armadillos infected with microfilariae displayed deficiencies in their bacteriocidal mechanisms and TNF-like production, but not in their endocytic capacity. …American Journal of Animal and Veterinary Sciences, Vol. 1, Issue 1 · 30 Jun 2006 · 6,659 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTowards Identifying Immunogenic Targets in Visceral Leishmaniasis: Role of 17kDa and 63kDa PhosphoproteinsShubhankar K Singh, Sanjiva Bimal, Diwakar S. Dinesh et al.We observed predominant phosphorylation at Protein Kinase C (PKC-α) residue in seven immunoreactive proteins of virulent Leishmania donovani parasites. These phosphoproteins were tested for their ability to stimulate T-cells for secretion of Macrophage Migration Inhibition Factor (MIF) in comparision to crude soluble antigen in Visceral Leishmaniasis (VL) patients. Two of these phosphorylated L. donovani antigens led Leishmania to present these … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,756 accessesView PDF Cite