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55 results for “Lymphocytes”

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Research ArticleOpen accessIn the abstractEffect of Storing Temperature on Hepatotoxicity and Nephrotoxicity of Ifosfamide in Female RatFalah Mohammed AzizProblem statement: Ifosfamide (IFO) is a cytotoxic alkylating drug used for the treatment of a variety of cancers, although it has been found to induce certain hematological, hepatotoxic and nephrotoxic side effects. This drug is widely used in developing country, especially Iraq, but without caring too much to the storing temperature due to low drug maintaining facilities. The present work … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 19 Mar 2012 · 7,883 accessesView PDFCite
Research ArticleOpen accessIn the abstractStimulatory Effects of Dihydroartemisinin on the Leucocyte Population of Wistar Albino RatsU. A. Utoh-Nedosa, P. A. Akah, C. O. Okoli et al.Problem statement: Five dosages of Dihydroartemisinin (DHA) which included 1 mg kg-1; a repeated dose of 1; 2; 60 and 80 mg kg-1 were administered orally to albino rats for 5 days. The results of the study showed that dihydroartemisinin treatment significantly elevated the total white cell count (p<0.01); the percentage neutrophil count (p<0.01) and the percentage lymphocyte count (p<0.05). … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 17 Nov 2011 · 7,350 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Immunomodulatory Effect: Selection of the Correct Targets for Immunostimulation StudySwee Keong Yeap, Mashitoh Binti Abd Rahman, Noorjahan Banu Alitheen et al.Problem statement: Numerous plants or remedies that are traditionally used for various diseases had been claimed to maintain general good health, particularly the immune system. With the advanced understanding on immunology and ethnopharmacology, study on the interaction of this herb with the immune system is critical to understand the safety and its efficacy as a potent immunomodulatory agent. Approach: Selecting … …American Journal of Immunology, Vol. 7, Issue 2 · 4 Nov 2011 · 10,736 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression of the CD44 Protein in the Heart Valves Affected with Rheumatic Heart DiseaseR. Vijayalakshmi, S. Nayar, K.M. CherianProblem statement: The primary aim was to study the expression of CD44 protein in the heart valves removed surgically for either stenosis or regurgitation and to study the morphology of valves using histochemical staining. Approach: We studied 107 valves which were collected from the International Centre for Cardio Thoracic and Vascular Diseases. Results: Aortic and mitral valves were obtained from … …American Journal of Infectious Diseases, Vol. 6, Issue 4 · 31 Dec 2010 · 7,406 accessesView PDFCite
Research ArticleOpen accessIn the abstractZinc Deficiency and Associated T-Cell Dysfunctioning among Human Immunodeficiency Virus SeropositivesM. Andrew Pradeep, M. Thiruvalluvan, V. Nalini, J. Stella MaryProblem statement: All the nutrients in the diet play a crucial role in maintaining an optimal immune response. In both, deficient and excessive intake of nutrients can have negative consequence on the immune status and susceptibility to a variety of pathogens. Zinc is an essential micronutrient for human growth development and immune function. It plays a vital role in structure … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 8,037 accessesView PDFCite
Research ArticleOpen accessIn the abstractSwarm Negative Selection Algorithm for Electroencephalogram Signals ClassificationNasser Omer Sahel Ba-Karait, Siti Mariyam Shamsuddin, Rubita SudirmanProblem statement: The process of epilepsy diagnosis from EEG signals by a human scorer is a very time consuming and costly task considering the large number of epileptic patients admitted to the hospitals and the large amount of data needs to be scored. Therefore, there is a strong need to automate this process. Such automated systems must rely on robust … …Journal of Computer Science, Vol. 5, Issue 12 · 31 Dec 2009 · 7,205 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical Evidence of Autologous Graft versus Tumor EffectLuis F. PorrataProblem statement: The infused alloreactive lymphocytes in allogeneic stem cell transplantation (Allo-SCT) lead to an unspecific immune response causing Graft-Versus-Tumor (GVT) effect and Graft-Versus-Host Disease (GVHD). The current dogma regarding the anti-tumor effect of GVT is only observed in the Allo-SCT and not in the autologous hematopoietic stem cell transplantation (AHSCT). Approach: This article reviewed the medical literature to show … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Jan 2009 · 7,506 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Unusual Association between Chromoblastomycosis and Jorge Lobo’s Disease in the Same Patient from the Amazon RegionMaurimelia M. da Costa, Silvia H. Marques da Silva, Hugo J. R. Almeida et al.A clinical case of co-infection Cladophialophora sp. and Lacazia loboi is described and in a same patient with an 18-year history of verrucous plaques and parakeloidal nodular lesions. A 50-yearold man, a laborer, living in the Anajás city, Para, Brazil (rural Amazon region), was seen at the Evandro Chagas Institute’s ambulatory. Histopathological analysis revealed intense hyperplasia and hyperkeratosis of the … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 3 · 30 Sep 2008 · 7,747 accessesView PDFCite
Research ArticleOpen accessIn the abstractCocaine: A Catalyst for Human Immunodeficiency Virus-Associated DementiaNavneet K. Dhillon, Milind Gadgil, Andy Rahardja et al.Injection drug use has been recognized as a major risk factor for AIDS from the outset of the epidemic. Cocaine, one of the most widely abused drugs in the United States can both impair the functions of macrophages and CD4+ lymphocytes and also activate HIV-1 expression in these cells. Cocaine is a multifactorial agent that acts globally to impair the … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 7,587 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetection of IL-17 and IL-23 in Plasma Samples of Children with AutismAmanda Enstrom, Charity Onore, Irva Hertz-Picciotto et al.Interleukin-23 (IL-23) is a survival factor for a newly described population of T lymphocytes, namely Th-17 cells, that secrete IL-17, tumor necrosis factor- alpha (TNFα) and IL-6. It has been shown that Th-17 cells are a pathogenic T cell subset involved in autoimmune and chronic inflammatory diseases. Based on the increasing evidence of immune dysfunction in autism, including possible autoimmune … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 8,223 accessesView PDFCite