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75 articles for “Disease Progression”

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Research ArticleOpen accessIn the abstractEffect of Streptozotocin-Induced Hyperglycemia on the Progression of Hepatocarcinogenesis in RatsChowdhury Mobaswar Hossain, Bhabani Sankar Satapathy, Laboni Mondal et al.Diabetes mellitus and hepatocellular carcinoma both have detrimental impact on health worldwide. Type II diabetes and liver cancer share many causative factors, but biological correlation between the two diseases still remains elusive. The study was aimed to evaluate the effect of induction of diabetes during the development of hepatocarcinogenesis in rats. Rats were divided into four groups namely, normal control, … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 4 Nov 2013 · 7,521 accessesView PDFCite
Research ArticleOpen accessIn the abstractPolymerase Chain Reaction Detection of Pasteurella multocida Type B: 2 in Mice Infected with Contaminated River WaterFaez Firdaus Jesse Abdullah, Mohammed Muqdad Khaleel, Lawan Adamu et al.Hemorrhagic septicemia is an acute, deadly disease of cattle and buffaloes associated with colossal economic loss in the livestock industry in the Asian regions particularly Malaysia. Therefore, this study was conducted to investigate on the Polymerase chain reaction detection of Pasteurella multocida type B: 2 in mice inoculated through different routes with river water contaminated with infected mice carcasses. Sixty … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 17 Sep 2013 · 7,396 accessesView PDFCite
Research ArticleOpen accessIn the abstractMicrobial Translocation and B Cell Dysfunction in Human Immunodeficiency Virus DiseaseWei JiangThe gut mucosal barrier disrupted in HIV disease, resulting in increased systemic exposure to microbial products such as Lipo Polys Accharide (LPS). The association of enhanced microbial translocation and B cell dysfunction in HIV disease is not fully understood. High dose and short term exposure of microbial Toll-Like Receptor (TLR) agonists were used as vaccine adjuvants, however, low dose and … …American Journal of Immunology, Vol. 8, Issue 2 · 30 Jun 2012 · 7,413 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling the Dynamics of Tuberculosis Transmission in Children and AdultsF. Nyabadza, M. KgosimoreProblem statement: The fight Against Tuberculosis (TB) has mainly focused on the adult population because children were perceived to pose a very low risk in TB transmission. This assumption ignores the potential risk children had as reservoirs of latent infections from which future cases evolve when they become adults. It was therefore important to investigate the dynamics of TB taking … …Journal of Mathematics and Statistics, Vol. 8, Issue 2 · 5 Jun 2012 · 7,155 accessesView PDFCite
Research ArticleOpen accessIn the abstractFunctional Neuroimaging in Dementia and other Amnesic Disorders: A Radiological ReviewLeonardo Caixeta, Renata Teles Vieira, Sergio Machado et al.Problem statement: The structural and functional neuroimaging have much to contribute to the cognitive neuroscience. Approach: We describe a radiological review of the major dementia syndromes and Mild Cognitive Impairment (MCI), included Alzheimer's disease, Lewy body dementia, Vascular dementia, Front temporal Lobar degeneration, Dementia associated with parkinsonism and other amnesic syndromes. Results: The different syndromes and diseases presenting with dementia … …Neuroscience International, Vol. 2, Issue 1 · 23 Nov 2011 · 7,501 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical and Functional Profile of Amyotrophic Lateral Sclerosis Patients: A One Year Follow UpMarco Orsini, Marcos R.G. de Freitas, Osvaldo J.M. Nascimento et al.Problem statement: Amyotrophic Lateral Sclerosis (ALS) is a progressive and degenerative disease that affects the anterior horn motor neurons of the spinal cord and pyramidal tracts. In Brazil, there are few epidemiological data on this disease. Recently, some important findings have been reported, allowing a better understanding on the underlying processes of neuronal death, as well as the characteristics of … …Neuroscience International, Vol. 2, Issue 1 · 6 Oct 2011 · 7,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractSensory Neuropathy Associated with Glucose Intolerance: A 35 Patients StudyGiseli Quintanilha, Osvaldo J.M. Nascimento, Marco Orsini, Camila PupeProblem statement: Peripheral neuropathy due to diabetes has been studied for several decades. Until recently, we associate the involvement of peripheral nerves with an inappropriate glycemic control in the most advanced stages of the disease. Currently, it is considered that the onset of the neural injury can occur in the initial phase of this metabolic abnormality, during the period of … …Neuroscience International, Vol. 2, Issue 1 · 26 Jul 2011 · 7,485 accessesView PDFCite
Research ArticleOpen accessIn the abstractCognitive-Enhancing and Antioxidant Activities of Quercetin Liposomes in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of Alzheimer’s Disease (AD). Antioxidant intake is beneficial to delay or inhibit the progression of this disease. Quercetin, a bioflavonoid in fruits and vegetables, has a powerful antioxidant activity both in vitro and in vivo. Claims that quercetin has many biological activities. However, quercetin is rapidly … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 31 Oct 2010 · 7,884 accessesView PDFCite
Research ArticleOpen accessIn the abstractUtilization of Specific Index for Measuring the Association between Periodontal Conditions and Coronary Artery DiseaseNavabi Nader, Farzaneh MehdizadehProblem statement: There is increasing evidence that periodontal disease could play a role in the Progression of coronary heart disease although there are conflicting results about this association in the literature and the difference of used periodontal scoring systems among the studies might be a reason. The purpose of this study was to evaluate a specific scoring system Periodontal Index … …Current Research in Dentistry, Vol. 1, Issue 1 · 30 Jun 2010 · 8,022 accessesView PDFCite
Research ArticleOpen accessIn the abstractNasal Administration of Quercetin Liposomes Modulate Cognitive Impairment and Inhibit Acetylcholinesterase Activity in HippocampusTerdthai Tong-Un, Supaporn Muchimapura, Wathita Phachonpai, Jintanaporn WattanathornProblem statement: Oxidative stress is a major factor implicated in the degeneration of cholinergic neurons in Alzheimer’s Disease (AD). Several reports have indicated that antioxidant intake is beneficial to delay or inhibit the progression of this disease. Presently, Acetylcholinesterase (AChE) inhibitors are the mainstay of therapy for AD. Quercetin, one of the flavonoids in fruits and vegetables, has a powerful … …Neuroscience International, Vol. 1, Issue 1 · 30 Jun 2010 · 7,173 accessesView PDFCite