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182 articles for “Diabetes”
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Research ArticleOpen accessEvery word in the titleThe Potential of VipAlbumin® to Chronic Inflammation in Type 2 Diabetes Mellitus Balb/C Mice ModelDinia Rizqi Dwijayanti, M. Sasmito Djati, Mansur Ibrahim, Muhaimin Rifa’iDiabetes Mellitus (DM) is one of diseases which have increasing number of sufferers every year. Almost all DM patients are type 2 DM. One of the causes of type 2 DM is a chronic inflammation due to an increase of circulating proinflammatory cytokines such as TNF-α, IFN-γ and IL-6. VipAlbumin® from snakehead fish extract is expected to be useful as … …American Journal of Immunology, Vol. 11, Issue 2 · 13 Jul 2015 · 7,612 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProtective Effect of Galactomannan Extracted from Iraqi Lycium barbarum L. Fruits against Alloxan-Induced Diabetes in RatsAdnan J.M. Al-FartosyLycium barbarum L. (Solanaceae) is widely used in Iraqi Ayurvedic medicine for the treatment of diabetes mellitus. The present investigation was done to evaluate the effects of polysaccharide (galactomannan) from Lycium barbarum L. Fruits (GLBF) on serum blood glucose, serum lipid profile and lipid peroxidation and antioxidant defence system in liver and kidney of alloxan-induced diabetic rats. GLBF was found … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 15 Dec 2014 · 7,653 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInfluence of Quercetin on Diabetes-Induced Alteration in CYP3A Activity and Bioavailability of Pioglitazone in RatsSudhir Niranjan Umathe, Pankaj Vinod Dixit, Jignesh Manubhai Vaghasiya, Nishant Sudhir JainProblem statement: Quercetin-a common bioflavonoid, is present in herbal preparations consumed by diabetic patients along with routine anti-diabetic agents. We recently showed that quercetin increases the bioavailability of pioglitazone in non-diabetic rats. Thus, present study investigated whether this pharmacokinetic interaction is also evident in diabetic animals, especially because diabetic subjects have altered gastrointestinal (GI) function and CYP3A activity. Approach: The … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,818 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAlmond Consumption Decreases Fasting and Post Prandial Blood Glucose Level in Female Type 2 Diabetes SubjectParul Choudhary, Saroj Kothari, Vimal SharmaProblem statement: Population studies indicate that individuals who regularly consume nuts have reduced risk for cardiovascular diseases and diabetes. The beneficial role of almonds has been established with respect to serum lipid profile however, its beneficial effects on glycemia is still to be established. Aim of the study was to investigate the response of almond feeding on fasting and post … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,092 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Alloxan-Diabetes on Gastrin-Releasing Peptide (GRP) Immunoreactivity in the Gastrointestinal Tract, of Sprague Dawley Rats and How This May Affect Some of the Diabetic ComplicationsEdward O. Uche-Nwachi, Camille V. MitchellGastrin-releasing peptide (GRP) is the mammalian analogue of bombesin. Both neuroendocrine peptides have similar distribution, functions and immunoreactivity. The immunoreactivity for GRP has been demonstrated in the esophagus, stomach and small intestine. This peptide is reported to have various biological and pharmacological properties, which include the release of gastrointestinal hormones, control of satiety, gastrointestinal motility and stimulation of cellular proliferation … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 31 Dec 2007 · 7,250 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBridging Innovation and Access: Randomized, Single-Dose, Open-Label, Parallel-Group Bioequivalence Study of Generic and Innovator Injection Semaglutide in IndiaMayur Madhav Mayabhate, Nitin Kapure, Akhilesh Sharma, Radhakrishna VaddemSemaglutide, a long-acting Glucagon-Like Peptide-1 (GLP-1) receptor agonist, is effective in improving glycemic control, reducing body weight, and lowering cardiovascular risk in Type 2 Diabetes Mellitus (T2DM). Limited accessibility of the innovator formulation underscores the need for bioequivalent generic alternatives. To assess the pharmacokinetic bioequivalence of a synthetic Semaglutide Injection (2 mg/1.5 mL) developed by Alkem Laboratories Ltd., India, compared … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 20 Apr 2026 · 2,626 accessesView PDFCite
Literature ReviewOpen accessIn the keywordsThe Relationship between Obesity, Insulin Resistance and Hypertension: A ReviewMasah Mardini, Lana Dardari, Maher Taha et al.Obesity is considered a global epidemic with detrimental health effects. It is linked to the development of conditions such as diabetes mellitus, hypertension, hyperlipidemia, coronary heart disease, atherosclerotic cerebrovascular disease, and higher mortality rates, among other conditions. This review elucidates the pathophysiology linking obesity, insulin resistance, type 2 diabetes, and hypertension and includes clinical trials that demonstrate these relationships. Electronic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 Aug 2024 · 5,076 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Sled Dog Model for Positive Health Effects of Weight Management and ExerciseLaura Falkenstein, Scott Jerome et al.Obesity is a significant risk factor for metabolic syndrome and type II diabetes. Physical activity and/or dietary modification can reduce the incidence of obesity. Marginal fitness levels limit the efficacy of exercise training, and most humans choose from a wide range of dietary strategies to lose weight. Despite these limitations, exercise in the absence of weight loss may offer protective … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 23 Feb 2023 · 6,151 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPredictive Modeling Applied to Structured Clinical Data Extracted from Electronic Health Records: An Architectural Hypothesis and A First ExperimentAlessandra Pieroni, Alessandro Cabroni, Francesca Fallucchi, Noemi ScarpatoPredictive analysis is one of current important issues in the healthcare context. A lot of patients’ input data can be obtained from their Electronic Health Records. In our research, we propose a general architecture named Health Prediction Architecture. Initially, we consider that data refer to strongly structured health datasets (no free text). Our objectives are related to exploring some problems … …Journal of Computer Science, Vol. 17, Issue 9 · 7 Sep 2021 · 6,571 accessesView PDFCite
Case ReportOpen accessIn the keywordsLessons Learned: Barriers to Hemoglobin A1c Monitoring in Rural Northern TanzaniaAndrea Fortson Knopp, Erika Metzler SawinIn sub-Saharan countries, Non-communicable Chronic Diseases (NCDs), including diabetes, are on the rise. Glycated hemoglobin (HbA1c) is a Point Of Care (POC) diagnostic tool for diabetic monitoring that is unavailable in many resource-constrained environments worldwide. Theoretically, HbA1c measurement is practical in these settings because fasting is not required, the test is not generally repeated before 120 days and travel time … …International Journal of Research in Nursing, Vol. 11, Issue 1 · 8 Jan 2021 · 6,228 accessesView PDFCite