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641 articles for “Clinical”
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Research ArticleOpen accessEvery word in the titleDietary Beta-1,3/1,6-Glucans Reduce Clinical Signs of Canine AtopyA. C. Beynen, D. H.J. Saris, P. M. Paap et al.Problem statement: There was evidence that beta-1,3/1,6-glucans modulate inflammatory activity. In an open, non-controlled trial, purified beta-1,3/1,6-glucans were found to improve the clinical signs of dogs with undefined chronic skin disorders. Given the design of that study, further work was required on the efficacy of beta-1,3/1,6-glucans in the treatment of canine atopy. Approach: The influence of a purified preparation of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 9 Jan 2012 · 9,979 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClinical and Functional Profile of Amyotrophic Lateral Sclerosis Patients: A One Year Follow UpMarco Orsini, Marcos R.G. de Freitas, Osvaldo J.M. Nascimento et al.Problem statement: Amyotrophic Lateral Sclerosis (ALS) is a progressive and degenerative disease that affects the anterior horn motor neurons of the spinal cord and pyramidal tracts. In Brazil, there are few epidemiological data on this disease. Recently, some important findings have been reported, allowing a better understanding on the underlying processes of neuronal death, as well as the characteristics of … …Neuroscience International, Vol. 2, Issue 1 · 6 Oct 2011 · 7,774 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImpact of Dietary Polydextrose on Clinical Signs of Canine OsteoarthritisA. C. Beynen, D. H.J. Saris, L. De Jong et al.Problem statement: Osteoarthritis is an inflammatory joint disease associated with loss of cartilage matrix. There is suggestive evidence that the intake of polydextrose fiber has anti-inflammatory activity. It was reasoned that polydextrose may have a positive influence on canine osteoarthritis. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of STA-LITE® polydextrose in … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 3 · 5 Oct 2011 · 9,052 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Study of Clinical Behavior in Intensive Care UnitGilly SmithProblem statement: In order to support the needs of the staff working in discrete areas of nursing, the attitudes, behaviors and needs of the group must first be articulated. Unfortunately, there has been little research conducted to understand the culture of what it is that health care workers think and feel and why they make the choices they do in … …International Journal of Research in Nursing, Vol. 1, Issue 1 · 30 Jun 2010 · 8,674 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOral Administration of Gelatin Hydrolysate Reduces Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled TrialA.C. Beynen, H.W. Van Geene, H.V. Grim et al.Problem statement: There are indications that the intake of gelatin hydrolysate has a beneficial impact on the clinical signs of osteoarthritis in dogs. Data from a controlled trial were required to substantiate these indications. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of a preparation of gelatin hydrolysate in the treatment of … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 18,245 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInfluence of Dietary Beta-1,3/1,6-Glucans on Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled TrialA.C. Beynen, E. LegersteeProblem statement: There are indications for a beneficial effect of beta-1,3/1,6-glucans on the clinical signs of dogs with osteoarthritis. Data from a controlled trial were necessary to prove or disprove the indications. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of a preparation of beta-1,3/1,6-glucans in the treatment of osteoarthritis. With the … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 10,105 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular Analysis of Coagulase Gene Polymorphism in Clinical Isolates of Methicilin Resistant Staphylococcus aureus by Restriction Fragment Length Polymorphism Based GenotypingM. Himabindu, D. Sugapriya Muthamilselvan, Dillip Kumar Bishi, Rama S. VermaProblem statement: To investigate coagulase gene variants through Restriction Fragment Length Polymorphism (RFLP) amongst clinical isolates of Methicillin-Resistant Staphylococcus Aureus (MRSA) collected from Chennai based hospitals. Approach: A total of 85 MRSA clinical isolates collected from various clinical sources were studied for the molecular typing purpose. To perform coagulase gene typing, the repeated units encoding hypervariable regions of the Staphylococcus … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,766 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClinical Evidence of Autologous Graft versus Tumor EffectLuis F. PorrataProblem statement: The infused alloreactive lymphocytes in allogeneic stem cell transplantation (Allo-SCT) lead to an unspecific immune response causing Graft-Versus-Tumor (GVT) effect and Graft-Versus-Host Disease (GVHD). The current dogma regarding the anti-tumor effect of GVT is only observed in the Allo-SCT and not in the autologous hematopoietic stem cell transplantation (AHSCT). Approach: This article reviewed the medical literature to show … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Jan 2009 · 7,506 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of Acute-phase Reactants, Immunologic Markers and other Clinical and Laboratory Parameters in Patients with Pneumonia and Non-pneumonic Lower Respiratory Tract InfectionsJulio Collazos, María del Mar Martínez, Fernando IzquierdoMore efficacious tools to distinguish pneumonia from other acute lower respiratory tract infections (OALRTI) in facilities where radiologic studies are not easily or rapidly available are desirable to select the patients who should undergo chest radiographs, to avoid unnecessary visits to the emergency wards of hospitals and to optimize health resources. To this end we analyzed the relevance of many … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 7,083 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIntroduction of Three Complementary Technologies into Clinical Medicine: Development of New Diagnostic and Prognostic ParametersGernot P. Tilz, Marco Wiltgen, Ulrike Demel et al.Molecular medicine leads us to understand some diseases at the molecular level. Examples are the analysis of immune complexes and receptor - anti receptor compounds used in clinical medicine. Structural changes of some serum proteins occur in inflammation, neoplasie and autoimmunity. The detection and analysis of such structural modifications may offer a new field for the diagnosis, prognosis and therapy … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 6,956 accessesView PDFCite