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55 results for “Cancers”
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Research ArticleOpen accessIn the abstractAlcohol Consumption and its Correlates Among Residents of Mining Town, Kitwe, Zambia: 2011 Population Based SurveyCosmas Zyaambo, Olusegun Babaniyi, Peter Songolo et al.Alcohol consumption is a risk factor for non-communicable diseases such as cardiovascular diseases, liver cirrhosis and cancers. It has also been associated with risky sexual behaviors, hence, attributed as a factor in the increase of HIV incidence and prevalence. A cross sectional study was conducted using a modified World Health Organizations Global Non Communicable Diseases (NCD) Surveillance Initiative NCD-STEPs 1and … …Current Research in Medicine, Vol. 4, Issue 1 · 29 Jan 2013 · 8,051 accessesView PDFCite
Research ArticleOpen accessIn the abstractCancerous Immunoglobulins and CA215: Implications in Cancer ImmunologyGregory LeeImmunoglobulins are typically expressed by B cells in our normal immune system. However, certain normal human tissues, such as hyperplastic epithelial cells, cells of the immunologically privileged sites and the majority of cancer cells, have also been found to be sites of immunoglobulin production. Current research is lacking in regards to the differential immunoglobulin expression, the underling mechanisms of action … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Sep 2012 · 8,946 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Storing Temperature on Hepatotoxicity and Nephrotoxicity of Ifosfamide in Female RatFalah Mohammed AzizProblem statement: Ifosfamide (IFO) is a cytotoxic alkylating drug used for the treatment of a variety of cancers, although it has been found to induce certain hematological, hepatotoxic and nephrotoxic side effects. This drug is widely used in developing country, especially Iraq, but without caring too much to the storing temperature due to low drug maintaining facilities. The present work … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 19 Mar 2012 · 7,887 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship Between Blood Fibrinogen Concentration and Pathological Features of Cancer Patients: A 139-case Clinical StudyDa-Yong Lu, Xue-Liang Chen, Min Huang et al.Angiogenesis and coagulation are among the most consistent host responses to the presence of a malignant tissue. Pathological angiogenesis and coagulation are often occurred in patients with solid tumors, especially in the occurrence of neoplasm metastasis and as targets for anti-metastatic drugs such as antiangiogenesis agents, coagulation-mediated agents and anticancer drugs. Since fibrinogen (Fib) is the most abundant and key … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 4 Sep 2010 · 7,871 accessesView PDFCite
Research ArticleOpen accessIn the abstractSkin Images SegmentationAli El-ZaartProblem statement: Image segmentation is a fundamental step in many applications of image processing. Skin cancer has been the most common of all new cancers detected each year. At early stage detection of skin cancer, simple and economic treatment can cure it mostly. An accurate segmentation of skin images can help the diagnosis to define well the region of the … …Journal of Computer Science, Vol. 6, Issue 2 · 28 Jul 2010 · 7,024 accessesView PDFCite
Research ArticleOpen accessIn the abstractPredicting the Severity of Breast Masses with Ensemble of Bayesian ClassifiersAlaa M. ElsayadProblem statement: This study evaluated two different Bayesian classifiers; tree augmented Naive Bayes and Markov blanket estimation networks in order to build an ensemble model for prediction the severity of breast masses. The objective of the proposed algorithm was to help physicians in their decisions to perform a breast biopsy on a suspicious lesion seen in a mammogram image or … …Journal of Computer Science, Vol. 6, Issue 5 · 31 May 2010 · 7,306 accessesView PDFCite
Research ArticleOpen accessIn the abstractRisk Assessment of Tobacco Types and Oral CancerAbdoul Hossain Madani, Abdolreza Sotoodeh Jahromi, Madhurima Dikshit, Debanshu BhaduriProblem statement: Oral cancer is one of the most common life threatening cancers all over the world, in particular Asian countries and tobacco is considered to be the most potent risk factor for oral cancer. This study was conducted to investigate the risk factors for oral cancer among the subjects from the studied area. Approach: A case-control study of 350 … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 10,083 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntrinsically Unstructured Proteins: Potential Targets for Drug DiscoveryPathan Salma, Chintan Chhatbar, Sriram SeshadriProblem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by their unstructured nature in the unbound state, provides a level … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,579 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,100 accessesView PDFCite
Research ArticleOpen accessIn the abstractBetter Understanding of the Immunosuppressive Link between the Lymphocytic Immune Cells and the Decreased Cell Mediated Immunity in Head and Neck Cancer PatientsA.S. Abdulamir, R.R. Hafidh, N. Abdulmuhaimen et al.The purpose of this study was to determine the phenotyping of Peripheral Blood Lymphocytes (PBL) in Head and Neck Cancers (HNCA) patients and to relate this with the level of Cell-Mediated Immunity (CMI) measured by in vitro lymphoproliferative assay, in order to evaluate immune suppression in HNCA patients and its possible mechanisms. Accordingly, one hundred twenty two HNCA patients and … …American Journal of Immunology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,306 accessesView PDFCite