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52 articles for “CD4+”
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Research ArticleOpen accessIn the abstractAn Exceptional Case Report of Primary Cutaneous Cryptococcosis in Human Immunodeficiency VirusA. S. Valan, S. Kumar, K. Ramalingam et al.Problem statement: Cryptococcosis is an infection caused by the encapsulated yeast Cryptococcus neoformans, a dimorphic fungus. In patients with AIDS, skin manifestations represent the second most common site of disseminated Cryptococcosis. Approach: Mr. A 42 year old farmer was referred from Voluntary Counseling and Testing Centre (VCTC) with positive HIV status to the outpatient department with one week history of … …American Journal of Immunology, Vol. 7, Issue 1 · 16 Aug 2011 · 8,278 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunodeficiency Provides Partial Protection from Bone Loss Induced by Castration and OvariectomyCedo M. Bagi, Edwin Berryman, Nels Hanson et al.Problem Statement: The interaction of osteoblasts and osteoclasts with cells of the immune system has been suggested as a contributing factor in the development of osteoporoses. Evidence from studies in rodents suggests that T cells play a significant role in bone loss following estrogen deficiency. The goal of this study was to investigate whether the lack of functional T cells … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,074 accessesView PDFCite
Research ArticleOpen accessIn the abstractTransforming Growth Factor-β: An Indirect Inducer of Th17 Cell Differentiation both in Human and Murine SystemJ. SchumannSince their first description only some years ago Th17 cells have become of vital importance in immunological research. However, the role of TGF-β in Th17 cell development is still a matter of controversial discussion. Predicted to have a key function in Th17 cell differentiation in the mouse TGF-β was shown to inhibit IL-17 production of human CD4+ T cells. Moreover, … …American Journal of Immunology, Vol. 6, Issue 2 · 30 Jun 2010 · 7,575 accessesView PDFCite
Research ArticleOpen accessIn the abstractMortality among HIV-Infected Patients in Resource Limited Settings: A Case Controlled Analysis of Inpatients at a Community Care CenterNirmala Rajagopalan, Joyce B. Suchitra, Anita Shet et al.Problem statement: Despite massive national efforts to scale up Antiretroviral Therapy (ART) access in India since 2004, the AIDS death rate was 17.2 per 100,000 persons during 2003-2005. In the era of HAART in resource poor settings, it is imperative to understand and address the causes of AIDS related mortality. This collaborative study aimed at defining the predictors of mortality … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,661 accessesView PDFCite
Research ArticleOpen accessIn the abstractCocaine: A Catalyst for Human Immunodeficiency Virus-Associated DementiaNavneet K. Dhillon, Milind Gadgil, Andy Rahardja et al.Injection drug use has been recognized as a major risk factor for AIDS from the outset of the epidemic. Cocaine, one of the most widely abused drugs in the United States can both impair the functions of macrophages and CD4+ lymphocytes and also activate HIV-1 expression in these cells. Cocaine is a multifactorial agent that acts globally to impair the … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 7,587 accessesView PDFCite
Research ArticleOpen accessIn the abstractInduction of a Soluble Anti-HIV-1 factor (s) with IFN-γ, IL-10, and β-Chemokine Modulating Activity by an Influenza-Bacterial Polyantigenic MixtureJosé W. Rodríguez, Nat O. Pagan, Mar C. Ocasio et al.Partial immune restoration may be obtained with highly active antiretroviral therapy (HAART), but specific anti-HIV-1 immune responses do not appear to improve substantially. We have demonstrated that a soluble factor(s) induced by a mixture of inactivated influenza and bacterial vaccines called polyantigenic immunomodulator (PAI), possesses strong immunoregulatory and anti- HIV-1 activities. In the present study, we show that culture fluids … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,845 accessesView PDFCite
Research ArticleOpen accessIn the abstractCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,009 accessesView PDFCite
Research ArticleOpen accessIn the abstractTowards Identifying Immunogenic Targets in Visceral Leishmaniasis: Role of 17kDa and 63kDa PhosphoproteinsShubhankar K Singh, Sanjiva Bimal, Diwakar S. Dinesh et al.We observed predominant phosphorylation at Protein Kinase C (PKC-α) residue in seven immunoreactive proteins of virulent Leishmania donovani parasites. These phosphoproteins were tested for their ability to stimulate T-cells for secretion of Macrophage Migration Inhibition Factor (MIF) in comparision to crude soluble antigen in Visceral Leishmaniasis (VL) patients. Two of these phosphorylated L. donovani antigens led Leishmania to present these … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,756 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Identification of Oral Cancer Stem Cells (CSC) within Commercially Available Cell LinesRobert Chauncey, Kai Hatch, Toni Jilka et al.Previous studies have demonstrated some tumors develop or maintain a small sub-population of cells with stem cell-like properties. This Cancer Stem Cells (CSC) may exhibit differential properties that allow their escape from traditional radiation or chemotherapy treatments and may therefore be responsible for cancer recurrence. Few studies have explored this phenomenon among oral cancer cell lines, therefore the objective of … …Current Research in Dentistry, Vol. 9, Issue 1 · 2 Jun 2018 · 12,719 accessesView PDFCite
Review ArticleOpen accessIn the abstractSpecific Markers for Hepatic Progenitor CellsMsy Rulan Adnindya, Indriyani, Ahmad Azmi Nasution, Isabella Kurnia LiemOne of mammalian organs that has remarkable ability to regenerate, liver, regenerates through the proliferation of hepatocytes or proliferation and differentiation of the stem cells resident. Some literatures states that these stem cells, the Hepatic Progenitor Cells (HPCs), are oval cells that have bipotential ability to be cholangiocytes and hepatocytes. However, the mechanisms of programming, activation of proliferation and maturation/differentiation … …OnLine Journal of Biological Sciences, Vol. 17, Issue 3 · 13 Jul 2017 · 9,286 accessesView PDFCite